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Smoking severity and GOLD-COPD Grade

Glutathione-S-transferases in lung and sputum specimens, effects of smoking and COPD severity

Glutathione-S-transferases in lung and sputum specimens, effects of smoking and COPD severity

... in COPD as shown in this study and in the previous investigations parallels with the initial induction and con- sequent dysfunction of the Nrf2 pathway in COPD ...

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Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity

... The analysis of our data allowed the direct quantifica- tion in human lung tissue of alveolar macrophages ex- pressing either M1 or M2 or no markers of polarization, and showed how this expression changed with disease ...

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The effect of changes to GOLD severity stage on long term morbidity and mortality in COPD

The effect of changes to GOLD severity stage on long term morbidity and mortality in COPD

... of GOLD severity stage over time and for the first to describe the association of GOLD severity stage change with poor ...cohorts, GOLD severity stage C is the least common ...

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Impact of using the new GOLD classification on the distribution of COPD severity in clinical practice

Impact of using the new GOLD classification on the distribution of COPD severity in clinical practice

... with COPD according to GOLD 2007 ...for GOLD staging and appropriate self-assessment and documented care for at least 1 year at outpatient ...

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Variation in Assignment of the COPD Patients into a GOLD Group According to Symptoms Severity

<p>Variation in Assignment of the COPD Patients into a GOLD Group According to Symptoms Severity</p>

... the gold standard for diagnosis, clas- sification and follow-up of the COPD patient until the document was updated in ...suspected COPD and a new classification system was proposed that combined ...

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COPD exacerbations by disease severity in England

COPD exacerbations by disease severity in England

... disease severity as outlined in the GOLD 2013 management strategy in the ...the GOLD categories and showed a large upward trend with increasing level of disease severity from GOLD A ...

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Identification of genetic variants in the TNF promoter associated with COPD secondary to&nbsp;tobacco smoking and its severity

Identification of genetic variants in the <em>TNF</em> promoter associated with COPD secondary to&nbsp;tobacco smoking and its severity

... Dovepress Genetic variants in the TNF promoter associated with COPD been described; 19 different altered biomarkers have also been reported, particularly those related to inflammation. Among these is TNF- α , ...

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Comorbidities and COPD severity in a clinic-based cohort

Comorbidities and COPD severity in a clinic-based cohort

... in GOLD A patients, which is not in agreement with the guidelines GOLD ...the GOLD classification are based on dyspnea and exac- erbations but not on ...symptomatic GOLD A patients could ...

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Smoking Cessation Interventions for COPD: A Review of the Literature

Smoking Cessation Interventions for COPD: A Review of the Literature

... A smoking cessation nurse delivered the experi- mental arm for 1 hour per day in groups of 4 – 8 people over 11 days, as part of a wider lifestyle intervention with additional input from a doctor, a ...

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Smoking cessation affects the natural history of COPD

Smoking cessation affects the natural history of COPD

... between smoking- cessation group and continuing-smoking ...assess COPD severity but was also independently associated with mortality from ...COPD. Smoking leads to increase in ...

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Systemic inflammation in COPD in relation to smoking status

Systemic inflammation in COPD in relation to smoking status

... on COPD. On the other hand, elevated serum AAT can also reflect a low-grade chronic inflamma- tory process in the lungs [18], which is considered a risk factor for COPD ...

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Application of the new GOLD COPD staging system to a US primary care cohort, with comparison to physician and patient impressions of severity

Application of the new GOLD COPD staging system to a US primary care cohort, with comparison to physician and patient impressions of severity

... new GOLD COPD assessment system adds chronic respiratory symptoms information and recent exacerba- tion history to reclassify persons into a two-dimensional matrix that should better characterize the ...

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COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma&ndash;COPD overlap syndrome

COPD assessment test and severity of airflow limitation in patients with asthma, COPD, and asthma&ndash;COPD overlap syndrome

... with COPD, 51 patients with ACOS, and 44 patients with chronic cough, treated at Saitama Cardiovascular and Respiratory Center from January 23, 2015 to August 31, 2015, were enrolled in this ...16 COPD was ...

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Effects of long-acting bronchodilators in COPD patients according to COPD severity and ICS use

Effects of long-acting bronchodilators in COPD patients according to COPD severity and ICS use

... with GOLD stage II disease, not only as a broncho- dilator but also in terms of improvement in dyspnoea and health status, with all improvements exceeding the threshold for a clinically relevant ...in COPD, ...

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Smoking history and emphysema in asthma&ndash;COPD overlap

Smoking history and emphysema in asthma&ndash;COPD overlap

... Dovepress smoking history and emphysema in aCO of patients with CAO and developed an algorithm for the diagnosis of COPD, asthma and other airway diseases with ...a smoking history risked being ...

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Health-related quality of life is related to COPD disease severity

Health-related quality of life is related to COPD disease severity

... gender, smoking sta- tus and socio-economic background was used as covari- ...of severity based on FVC % predicted nor- mal was also investigated with the same model with clas- sification into four groups: ...

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Multiple biomarkers predict disease severity, progression and mortality in COPD

Multiple biomarkers predict disease severity, progression and mortality in COPD

... Enrollment Centers. Table S11. Baseline Characteristics of Subjects with Biomarker Data Compared with Entire COPDGene Cohort. Table S12. Correlation Between Biomarkers. Table S13. Biomarkers Associated with Mortality. ...

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Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

Effects of aclidinium on determinants of COPD severity: symptoms and quality of life

... a COPD patient, including chronic heart failure, anemia, cachexia, malnutrition, ...the severity of the airflow obstruction but also more generally the sever- ity of a COPD ...The GOLD ...

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Adjusting for COPD severity in database research: developing and validating an algorithm

Adjusting for COPD severity in database research: developing and validating an algorithm

... severe COPD according to GOLD (stages II to ...of COPD included age of 40 years or over, a smoking history of at least 10 pack-years, a post-bronchodilator FEV 1 -%predicted of 70% or less, ...

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Active smoking and COPD phenotype: distribution and impact on prognostic factors

Active smoking and COPD phenotype: distribution and impact on prognostic factors

... quitting smoking than patients with more severe ...of smoking cessation between former smokers and nonsmokers concluded that a relatively long period of time was needed before quitters achieved level of ...

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