Smooth Muscle
Smooth Muscle. Smooth Muscle Structure
... 9Capable of prolonged tonic contraction – the pace of cross-bridge cycling in smooth muscle is about 1/10 to 1/300 that of skeletal muscle. However, the fraction of time that cross-bridges remain ...
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Smooth muscle of the dorsal aorta shares a common clonal origin with skeletal muscle of the myotome
... in the dorsal aorta are not of neural crest origin and that, as expected, neural crest cells do not give rise to vascular smooth muscle in the trunk (Le Douarin and Kalcheim, 1999). Further confirmation was ...
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CF airway smooth muscle transcriptome reveals a role for PYK2
... of smooth muscle dysfunction absent ...airway smooth muscle transcriptome using physiologically relevant ...airway smooth muscle defects in CF ...airway smooth ...
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Retinoic acid signaling is essential for airway smooth muscle homeostasis
... (hyperplasia). Smooth muscle hypertro- phy is associated with an increase in the expression of contractile proteins and cellular contractility ...the smooth muscle contractile proteins α-SMA ...
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Expression of smooth muscle cell phenotype by rat mesangial cells in immune complex nephritis Alpha smooth muscle actin is a marker of mesangial cell proliferation
... alpha-smooth muscle actin in a mesangial pattern, correlating with the onset of proliferation, and persisting until day ...the smooth muscle actin-positive cells were actively ...prevented ...
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Bronchospasm and its biophysical basis in airway smooth muscle
... become compromised, not only when the peribronchial adventitia undergoes cytokine-driven inflammatory thick- ening, but also when the lung loses elastic recoil, or tidal lung expansion becomes diminished. These instances ...
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The characterisation of human detrusor smooth muscle cell cultures
... Spectrum of cells from fibroblast through to smooth muscle cell (Lau & Chacko 1996) as both cell types express smooth muscle myosin. In this paper they described two morphological types of ...
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Origins of increased airway smooth muscle mass in asthma
... airway smooth muscle mass, in part due to smooth muscle hyperplasia, is a very significant component of airway ...airway smooth muscle ...airway smooth muscle ...
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IP3 receptors regulate vascular smooth muscle contractility and hypertension
... adult smooth muscle cells, demonstrating that all 3 IP 3 R channels are substantially expressed in VSMCs, which is consistent with several prior studies ...
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Mechanism of rhinovirus induced changes in airway smooth muscle responsiveness
... bronchial smooth muscle (HBSM) tissue was also obtained from patients undergoing lung resection for peripheral lung carcinoma and having no evidence of obstructive lung disease, as assessed by routine ...
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The effects of inflammatory mediators on endothelial and smooth muscle function in vivo
... arginine:nitric oxide pathway but extends to production of dilator prostanoid and persists long after the smooth muscle changes have returned to normal. The effect appears to be generated locally within the ...
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Immunohistochemical Analysis of p16 Expression in Uterine Smooth Muscle Tumors
... uterine smooth muscle tumors, several recent reports show frequent overexpression of p16 in uterine leiomyosarcoma compared with ...in smooth muscle tumors, however, has not been well ...
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-induced injury of human vascular smooth muscle cells (HVSMCs)
... muscle cell (VSMC) apoptosis in the atheros- clerotic plaque, leading to plaque instability and rupture associated with atherosclerosis and restenosis [11, 12]. Thus, the development of protective strategies for ...
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The effect of caffeine on excitation contraction coupling in skeletal and smooth muscle
... The observation that caffeine reduces the size of both phasic and tonic components of the KCl-induced contracture supports the hypothesis that caffeine reduces smooth muscle membrane cal[r] ...
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THE EFFECT OF NOR EPINEPHRINE ON THE ELECTROLYTE COMPOSITION OF ARTERIAL SMOOTH MUSCLE
... These electrolyte shifts in arterial wall can best be explained by assuming that nor-epinephrine affects the membrane of the smooth muscle cells allowing for a net loss of potassium and [r] ...
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Specific receptors for leukotriene C4 on a smooth muscle cell line
... intact smooth muscle cell line, DDT1 MF-2 cells derived from the Syrian hamster vas ...DDT1 smooth muscle cell line is specific for a single constituent, LTC4, of slow reacting ...
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A novel vascular smooth muscle chymase is upregulated in hypertensive rats
... vascular smooth muscle ...artery smooth muscle cells from spontaneously hypertensive than in corresponding tissues from normotensive ...transfected smooth muscle cells and showed ...
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The role of gap junctions in the excitability of the myometrial smooth muscle network
... interconnected smooth muscle cells, forming an excitable medium (Garfield et ...individual muscle cells as well as the strength of their interconnections (Blanks et ...
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Propagated repolarization of simulated action potentials in cardiac muscle and smooth muscle
... We recently modeled propagation of APs of cardiac mus- cle and smooth muscle using the PSpice program for cir- cuit design and analysis [16-18]. Like the mathematical simulation published in 1977 [3] and ...
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A constitutive model for cytoskeletal contractility of smooth muscle cells
... of smooth muscle cells, fibroblasts and mesenchymal stem cells on a bed of PDMS microposts [6], the formation of stress fibres perpendicular to the direction of cyclic stretching [7] as well as the response ...
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