• No results found

snake venom metalloproteinase

Unusual stability of messenger RNA in snake venom reveals gene expression dynamics of venom replenishment.

Unusual stability of messenger RNA in snake venom reveals gene expression dynamics of venom replenishment.

... confirmed venom as a valid biological resource of most protein-encoding mRNA tested in this study, we collected venom samples from eight puff adders (of varying size/age, sex and geographic origin) at ...

10

Anti-thrombotic agents derived from snake venom proteins

Anti-thrombotic agents derived from snake venom proteins

... Viperidae snake venoms profoundly affect blood coagu- lation and platelet ...many venom components including ADPase, snake venom metalloproteinase (SVMP), phospholipase A2, GPIb and IX ...

5

Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom.

Venom-related transcripts from Bothrops jararaca tissues provide novel molecular insights into the production and evolution of snake venom.

... of snake toxins in the context of their co-option to the venom gland rarely account for nonvenom snake genes that are paralogous to toxins, and which therefore represent important connectors to ...

13

Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus)

Coagulating Colubrids: Evolutionary, Pathophysiological and Biodiscovery Implications of Venom Variations between Boomslang (Dispholidus typus) and Twig Snake (Thelotornis mossambicanus)

... procoagulants. Snake venoms are unique in their use of procoagulant toxins for predatory ...the venom of ...typus venom than T. mossambicanus. In addition to being a faster clotting venom, ...

20

Expression and characterization of a novel recombinant cytotoxin II from Naja naja oxiana venom: A potential treatment for breast cancer

Expression and characterization of a novel recombinant cytotoxin II from Naja naja oxiana venom: A potential treatment for breast cancer

... atra venom, showed the induced apoptosis of K562 cells occurred through up-regulating Bax and endonuclease G and downregulating of Bcl-X ...acutus snake venom arrests cancer cells during the sub-G1 ...

28

The snake with the scorpion’s sting: Novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus)

The snake with the scorpion’s sting: Novel three-finger toxin sodium channel activators from the venom of the long-glanded blue coral snake (Calliophis bivirgatus)

... crude venom and pure toxins were potent on both avian neuromuscular organ bath preparations and mammalian ion-channels FLIPR assays (Figures 1 and ...the venom may be three times less potent than that of α ...

21

Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.

Comparative venom gland transcriptome surveys of the saw-scaled vipers (Viperidae: Echis) reveal substantial intra-family gene diversity and novel venom transcripts.

... In addition to the discovery of LAL, two singleton tran- scripts were identified (additional file 2) from the Echis vgDbESTs as novel Serpentes zinc-dependent metal- lopeptidases [67]. A transcript exhibiting 67% ...

12

Identification and therapeutic application of molecular parallels between parasites, parasitic vectors and snake venom

Identification and therapeutic application of molecular parallels between parasites, parasitic vectors and snake venom

... Reid venom research unit, to devise 6–12 overlapping AA peptides, a set of chimeric epitope candidate immunogens best representing the conformation of the native epitopes (Wagstaff et ...of venom-induced ...

193

Fatal snake bite in a brown bear (Ursus arctos L.): A case report

Fatal snake bite in a brown bear (Ursus arctos L.): A case report

... from snake venom in animals is an emergency which requires immediate attention or otherwise, the delayed and inadequate treatment leads to untoward consequences and ...deadly venom of some species. ...

5

Characterisation of Venom Induced Consumption Coagulopathy (VICC) in patients with Haemotoxic Snake Bite and the effects of Blood Products on Coagulation Parameters

Characterisation of Venom Induced Consumption Coagulopathy (VICC) in patients with Haemotoxic Snake Bite and the effects of Blood Products on Coagulation Parameters

... injecting venom evolved over millions years ago ...Viperidae, venom glands are situated behind the eye, surrounded by compressor ...The venom flows through a groove to the tip of the ...Colubridae ...

129

Ontogenetic variations in the venom proteome of the Amazonian snake Bothrops atrox

Ontogenetic variations in the venom proteome of the Amazonian snake Bothrops atrox

... atrox snake spec- imens was done based on the total lenght of wild specimens according to Martins and Oliveira (1998) ...the venom glands of specimens longer that 50 cm, and with the aid of a Pasteur ...

14

The identification and characterisation of antimicrobial peptides from snake and scorpion venom

The identification and characterisation of antimicrobial peptides from snake and scorpion venom

... Recently certain three fingered toxins have been shown to exhibit antimicrobial activity. Kao et al (2011) examined the antimicrobial properties of y toxin, a cardiotoxin isolated from the elapids Naja nigricollis (black ...

291

Phylogenetic analysis of metalloprotease from transcriptome of venom gland of Hemiscorpius lepturus

Phylogenetic analysis of metalloprotease from transcriptome of venom gland of Hemiscorpius lepturus

... Hemiscorpius lepturus is a dangerous scorpion and referred to health concern issue in Khuzestan, Iran. The venom of H.lepturus is cytotoxic and its effect is similar to spider Loxosceles reclusa. ...

5

NEUTRALIZATION OF THE LETHAL EFFECT OF BITIS ARIETANS VENOM BY EUPHORBIA COTINIFOLIA LEAF EXTRACT

NEUTRALIZATION OF THE LETHAL EFFECT OF BITIS ARIETANS VENOM BY EUPHORBIA COTINIFOLIA LEAF EXTRACT

... against snake envenomation, especially local ...of snake venom, only a few attribute such activity to certain chemical compounds identified in them, and even less are concerned with a possible ...

9

Venomous snake bites: clinical diagnosis and treatment

Venomous snake bites: clinical diagnosis and treatment

... venomous snake that lives near rivers, ponds, and paddy fields, the same habitat as ...the venom gland duct opens at the base of the fang (Figure ...this snake has long been considered non-venomous ...

9

Rapid ligand fishing for identification of acetylcholinesterase binding peptides in snake venom reveals new properties of dendrotoxins

Rapid ligand fishing for identification of acetylcholinesterase binding peptides in snake venom reveals new properties of dendrotoxins

... Recent advances in separation science and detection technologies have fueled research into adjusted, advanced and/or new bioactivity screening formats for venom profiling. High-resolution screening, for example, ...

8

Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines

Snake venom causes apoptosis by increasing the reactive oxygen species in colorectal and breast cancer cell lines

... Abstract: Snake venom possesses various kinds of proteins and neurotoxic polypeptides, which can negatively interfere with the neurotransmitter signaling ...the snake venom as an anticancer ...

14

Control of venom production and secretion by sympathetic outflow in the snake Bothrops jararaca

Control of venom production and secretion by sympathetic outflow in the snake Bothrops jararaca

... for venom production, the effect of pharmacological denervation created by reserpine application on the morphology of venom gland secretory cells was ...evaluated. Venom could not be collected in ...

10

Comprehensive snake venomics of the Okinawa Habu pit viper, Protobothrops flavoviridis, by complementary mass spectrometry-guided approaches

Comprehensive snake venomics of the Okinawa Habu pit viper, Protobothrops flavoviridis, by complementary mass spectrometry-guided approaches

... This snake is endemic to 25 islands between Japan and Taiwan, whereas the largest areas of distribution are the Amami (Kagoshima Prefecture) and the Okinawa Islands (Okinawa ...of snake envenomation ...

17

Contrasting Modes and Tempos of Venom Expression Evolution in Two Snake Species

Contrasting Modes and Tempos of Venom Expression Evolution in Two Snake Species

... and Wilkinson 1997), and this measure has been shown to be a useful proxy for the relative amount of a specific protein by weight (Gibbs et al. 2009). However, this process gener- ates compositional data, with each peak ...

20

Show all 1499 documents...

Related subjects