Some Novel Benzimidazole
Design, Synthesis, Characterization and Biological Evaluation of Some Novel Benzimidazole (Schiff’ Base) Derivatives as Anti-Tubercular Agents against INHA
... CHARACTERIZATION AND BIOLOGIGAL EALUATION OF SOME NOVEL BENZIMIDAZOLE(SCHIFF’S BASE) DERIVATIVES AS ANTITUBERCULAR AGENTS AGAINST INHA” submitted by J.ROBERT DILTON bearing Register No.261615706 in ...
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Synthesis, Characterization and Antibacterial Evaluation of some Novel Benzimidazole Derivatives Containing 1,3,4-Thiadiazole Moiety.
... To the solution of compounds (1) (0.02mole ) in absolute ethanol(60 ml) the 1,3,4- thiadiazole-2,5-dithiol (4) (0.01 mole) and fused sodium acetate (0.02 mole) were added and the mixture was refluxed for 12 hrs, after ...
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Synthesis and Biological Evaluation of Some Novel Benzimidazole Derivative with Aspirin As Potent Antimicrobial & Antifungal Agents L.
... Aspirin (Acetyl Salicylic acid) have analgesic and anti-inflammatory activities. Aspirin undergoes reaction with O-phenylenediamine and replace the -OOH group in the presence of dilute (10%) hydrochloric acid. These ...
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Synthesis, Anti Tumor, Anti Diabetic, and Anti Asthmatic Activitives of Some Novel Benzimidazole Derivatives
... of novel substituted benzimidazole derivatives by the condensation of different diamines with anthranilicacid were ...the benzimidazole derivatives were reacted with different aromatic acid chlorides ...
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SYNTHESIS, CHARACTERIZATION AND EVALUATION OF BIOLOGICAL ACTIVITY OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES
... [1] Benzimidazole is a heterocyclic aromatic organic ...of novel benzimidazole derivative remains a main focus of medicinal ...research. Benzimidazole is a group of substances have found ...
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SYNTHESIS, CHARACTERIZATION AND IN VITRO ANTIMICROBIAL EVALUATION OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES BEARING HYDRAZONE MOIETY
... Finally, benzimidazole-hydrazone derivatives 6a-l were synthesized by treatment of 5a-d with substituted aldehydes in the presence of ethanol and little acetic ...
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“SYNTHESIS, ANTIMICROBIAL AND ANTHELMINTIC ACTIVITY OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES” by Srikanth Lingala*, Raghunandan Nerella, K.R.S.Sambasiva Rao, India.
... proposed benzimidazole derivatives were synthesized ...of benzimidazole derivatives, 19 and 20 showed good antibacterial activity against all the organisms employed for the antibacterial activity and ...
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SYNTHESIS, CHARACTERIZATION AND PHARMACOLOGICAL SCREENING OF SOME NOVEL BENZIMIDAZOLE DERIVATIVES
... of benzimidazole have been successfully synthesized and screened for analgesic activity by tail-flick method in mice, anti-inflammatory activity by carrageenan- induced rat paws edema method, antimicrobial ...
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Synthesis, antimicrobial and anthelmintic activity of some novel benzimidazole derivatives
... proposed benzimidazole derivatives were synthesized ...of benzimidazole derivatives, 19 and 20 showed good antibacterial activity against all the organisms employed for the antibacterial activity, compound ...
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Synthesis and investigation of mass spectra of some novel benzimidazole derivatives
... Condensation of 2-[2-thionyl acetyl] benzimi- dazole (3) with hydrazine hydrate in dimethyl for- mamide yielded the corresponding 2-(5-thionyl- pyrazol-3-yl)benzimidazole (7) and 2-[(β-2-thio- nyl-β-hydrazino) ...
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Synthesis, characterization and biological studies of some novel benzimidazole derivatives
... And the structures of these compounds were established on basis of analytical and spectral data. The newly synthesized compounds were evaluated for their antibacterial and antifungal activities. Among all the active ...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME BENZIMIDAZOLE DERIVATIVE WITH IBUPROFEN
... Some novel benzimidazole derivatives were synthesized with ibuprofen and evaluated for its activity. This compound showed notable antibacterial activity against gram-positive organisms and ...
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SYNTHESIS OF SOME SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR ANTIBACTERIAL ACTIVITY
... of benzimidazole derivatives dates back to the early sixties; since then hundreds of compounds endowed with several pharmacological activities have been ...The benzimidazole derivatives with their fused ...
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SYNTHESIS AND ANTIMICROBIAL ACTIVITY OF SOME NEWER BENZIMIDAZOLE DERIVATIVES
... 10. HTY Fahmy, SM Rida, Soad AM El-Hawash, Aly A. Hazzaa, MM Mostafa. Synthesis of novel benzofuran and related benzimidazole derivatives for evaluation of In-Vitro, Anti- HIV-1, anticancer and ...
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SYNTHESIS AND ANTIFUNGAL ACTIVITY OF SOME SUBSTITUTED BENZIMIDAZOLE ANALOGUES
... cyclization with formation o f 1,3,4-thiadiazole rings. This reaction may be useful for combinational syntheses of N-1 substituted benzimidazole analogue having various X substitution with a view to test for ...
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Investigation of Benzimidazole Compound as a Novel Corrosion Inhibitor for Mild Steel in Hydrochloric Acid Solution
... Non-toxic benzimidazole and its derivatives have been proved excellent inhibitors for mild steel ...Planar benzimidazole ring displays large projected area on metal surface and will show good inhibition ...
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Synthesis of some novel pyrrolidine, thiomorpholine, pyrimidine and pyridine derivatives containing benzimidazole moiety of expected antiviral and antimicrobial activity
... N-(4-(1H-benzo[d]imidazol-2-yl) phenyl-2-chloroacetamide (2) was prepared from the interaction of 4-(1H- benzimidazol-2-yl)benzenamine (1) [26] with chloroacetyle chloride in presence of triethyl amine according to the ...
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SYNTHESIS AND EVALUATION OF SOME SUBSTITUTED BENZIMIDAZOLE DERIVATIVES FOR THEIR ANTIINFLAMMATORY ACTIVITY
... agents. Benzimidazole is one of the commonly used nucleus. Role of Benzimidazole in medicinal chemistry is well ...of Benzimidazole was realized when it was identified as a part of vitamin B 12 ...
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SYNTHESIS OF NOVEL BENZOPYRONE SUBSTITUTED BENZIMIDAZOLE ANALOGUES AS ANTIBACTERIAL AGENTS
... both benzimidazole and benzopyrone derivatives have been reported to possess antibacterial activity, presence of these two heterocycles in a single molecule should also have the desired antibacterial ...synthesize ...
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DESIGN, SYNTHESIS & EVALUATION OF NOVEL SUBSTITUTED FLUOROQUINOLONE BENZIMIDAZOLE ANTIBACTERIALS
... A series of fluoroquinolone-benzimidazole hybrid was prepared and characterized by NMR, MS, and IR. The synthesized substituted fluoroquinolones were found pure; satisfactory in yield with reproducible results ...
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