Spontaneously Hypertensive Rats
Original Article Effect of losartan with folic acid on plasma homocysteine and vascular ultrastructural changes in spontaneously hypertensive rats
... thirty spontaneously hypertensive rats (SHR) involved and randomly divided into three groups (n=10): SHR-C group (control), SHR-L group (losartan 25 mg·kg - 1 ·d -1 ), SHR-L+Y group (losartan 25 ...
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Original Article Chaihu Shugan Powder attenuates Liver Qi stagnation type of metabolic syndrome in spontaneously hypertensive rats by upregulating liver X receptor-alpha
... in spontaneously hypertensive rats (SHR) by combina- tion of a high-fat and high-sucrose diet with Bondage of Modern Stimulation Method for 12 ...group. Rats in the control group were further ...
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Impairment of selectin mediated leukocyte adhesion to venular endothelium in spontaneously hypertensive rats
... between spontaneously hypertensive rats and Wistar Kyoto ...Kyoto rats, 10 microM histamine as well as 500 microM tertbutyl hydroperoxide promoted a significant reduction of venular leukocyte ...
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Blood–brain and blood–cerebrospinal fluid barrier permeability in spontaneously hypertensive rats
... Recent work by our group showed that the ISF drainage towards the ventricular system is enhanced in the hip- pocampus of spontaneously hypertensive rats (SHR) [11]. This animal model recapitulates ...
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Decreased Adrenal Responsiveness to Angiotensin II: A Defect Present in Spontaneously Hypertensive Rats: A POSSIBLE MODEL OF HUMAN ESSENTIAL HYPERTENSION
... genetically hypertensive rats, adrenal responsiveness to A II was determined in three groups of rats; spontaneously hypertensive rats (SHR), normotensive Wistar rats ...
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Role of Nitric Oxide, Produced by nNOS in the Regulation of Water and Electrolyte Excretion in Spontaneously Hypertensive Rats
... There are a number of surveys, showing the unique role of NO in the regulation of renal medullar perfusion, sodium homeostasis and arterial blood pressure. Experimental data consider that NO, produced by macula densa ...
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Altered Cellular Kinetics in the Growth Plate of the Femoral Head of Spontaneously Hypertensive Rats
... disease. Spontaneously hypertensive rats have proven to be a good model for studying LCP ...of spontaneously hypertensive rats ...SHR rats were divided into two groups: ...
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Effect of heme arginate administration on blood pressure in spontaneously hypertensive rats
... of spontaneously hypertensive rats (SHR) as compared with those of normotensive, Wistar-Kyoto (WKY), control rats during the period of rapid elevation of blood ...
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Original Article Notoginsenoside R1 reduces blood pressure in spontaneously hypertensive rats through a long non-coding RNA AK094457
... using spontaneously hypertensive rats (SHR), after NR1 treatment, we found NO production and induce iNOS expression increases in rats thora- coabdominal aortic and in rats vascular ...
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Original Article Bone marrow mesenchymal stem cells ameliorate neurological deficits and blood-brain barrier dysfunction after intracerebral hemorrhage in spontaneously hypertensive rats
... male spontaneously hypertensive rats (SHR) were subjected to ICH by intracerebral injection with autologous blood, Wistar-Kyoto (WKY) rats were employed as ...in spontaneously ...
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Sympathetic Hyperactivity during Hypothalamic Stimulation in Spontaneously Hypertensive Rats
... hypertensive rats. Basal sympathetic nerve activity was higher in spontaneously hypertensive rats than in either normotensive ...
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Cardiac remodeling and myocardial dysfunction in obese spontaneously hypertensive rats
... Obese spontaneously hypertensive rats (SHR-ob) exhibit hyperinsulinemia and demonstrate glucose intolerance in response to oral glucose load although they were not overtly diabetic according to ...
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Effects of particulate matter on the pulmonary and vascular system: time course in spontaneously hypertensive rats
... in spontaneously hypertensive rats. This is supported by the fact that, in the range of these doses, biological responses such as pulmonary inflammation, oxidative stress and effects observed in the ...
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Cerebrospinal fluid is drained primarily via the spinal canal and olfactory route in young and aged spontaneously hypertensive rats
... aged spontaneously hypertensive rats (SHR) because their cerebral ventricular volume is thought to increase with age [36,37], which, in addition to the hypertension, may affect CSF ...
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Atrial natriuretic peptide regulation of noradrenaline release in the anterior hypothalamic area of spontaneously hypertensive rats
... In spontaneously hypertensive rats (SHR), high NaCl diets increase arterial pressure and sympathetic nervous system activity by decreasing noradrenaline release in the anterior hypothalamic area ...
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Enrichment Discrimination Behavior in Spontaneously Hypertensive Rats
... among spontaneously hypertensive rats, subpopulations that diverge in attention to objects enriching an empty cross-maze; 2) To evaluate effect of clinically efficient drug for treatment of attention ...
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Increased cyclic guanosine monophosphate production and overexpression of atrial natriuretic peptide A receptor mRNA in spontaneously hypertensive rats
... messenger. Spontaneously hypertensive rats (SHR) have elevated plasma ANP levels, but manifest an exaggerated natriuretic and diuretic response to exogenous ANP when compared ...
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Pulmonary vasoreactivity in spontaneously hypertensive rats - Effects of endothelin-1 and leptin
... negatively regulates α1-agonists- and endothelin-1-induced contraction through a basal endothelial NO release [33-35], which is partly lost in spontaneously hypertensive rats [36-38]. The imbalance ...
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Atrial arrhythmia in ageing spontaneously hypertensive rats: unraveling the substrate in hypertension and ageing
... The SHR is the most widely studied experimental model of hypertension. However, it remains uncertain whether we can directly extrapolate our findings to the wide range of human hypertensive syndromes. To ...
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Parecoxib is neuroprotective in spontaneously hypertensive rats after transient middle cerebral artery occlusion: a divided treatment response?
... A large number of factors including age, environmental enrichment, exercise, growth, and neurotrophic sub- stances influence neurogenesis in the adult brain [20-23]. Kumihashi et al. [54] were the first to address the ...
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