stability indicating and method validation
Stability indicating RP-HPLC method for simultaneous determination of pyrimethamine and sulfamethoxypyrazine in pharmaceutical formulation: Application to method validation
... An additional peak was observed for acid degradation at retention time 2.9 minutes indicating degradation of 7.6% for simultaneous analysis of PYR and SLP (Fig. 4). Additionally, basic degradation studies also ...
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A validated stability-indicating HPLC method for determination of varenicline in its bulk and tablets
... the stability- indicating assay for ...a stability- indicating method for determination of VRC in its bulk drug and pharmaceutical tablets is essential, particularly, such methods have ...
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Development and Validation of Stability Indicating LC Method for Olmesartan Medoxomil
... inherent stability characteristics, leading to separation of degradation products and hence supporting the stability of the proposed analytical ...for stability sam- ples should be stability ...
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Development and validation of a stability indicating rp hplc method for simultaneous determination of haloperidol and benzhexol in pharmaceutical combined dosage forms
... precise stability indicating reversed- phase high performance liquid chromatographic method was developed for the simultaneous estimation of Haloperidol and Benzhexol in bulk and combined ...
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Development and validation of stability indicating HPTLC method for determination of Prasugrel
... and stability indicating (in accordance with ICH guidelines) High- Performance Thin Layer Chromatographic method of analysis for Prasugrel was developed, to resolve drug response from that of their ...
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Development and validation of stability indicating HPTLC method for determination of fluindione
... the method, recovery studies were carried out by adding standard drug to sample at three different levels 80, 100 and 120 ...the method is accurate for estimation of drug in tablet dosage ...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPTLC METHOD FOR DETERMINATION OF TROXIPIDE
... To check the repeatability, the response of sample solution was recorded six times. The intraday and inter day precision was performed as per the procedure given in previous section. For both repeatability and ...
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DEVELOPMENT AND VALIDATION OF STABILITY-INDICATING HPLC METHOD FOR DETERMINATION OF BOCEPREVIR
... developed method is stability indicating, since the drug peak was found to be pure as confirmed by peak purity profiling ...The method is specific, accurate, precise, and robust and can be ...
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Development and validation of stability indicating RP-HPLC method for voriconazole
... A stability-indicating method was developed, which resolved all the degradation products formed under variety of ...The method proved to be simple, accurate, precise, speciÞ c and ...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING ASSAY METHOD FOR DETERMINATION OF FELODIPINE IN TABLET DOSAGE FORM
... HPTLC method and Chromatographic condition In the proposed HPTLC method, the samples were streaked on the pre-coated TLC plates in the form of a narrow band 6 mm in length, 10 mm from the bottom and margin ...
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Development and Validation of Stability Indicating HPLC Method for Estimation of Dapsone
... (RP-HPLC) method for estimation of The aim of the present study was to develop a validated stability indicating ...RP-HPLC method was developed using neosphere C 18 (150 x ...The method ...
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Development and Validation of a Stability Indicating HPLC Assay Method for Determination of Warfarin Sodium in Tablet Formulation
... reversed-phase stability indicating high performance liquid chromatography [HPLC] assay method validated the for determination of warfarin in solid pharmaceutical dosage ...
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DEVELOPMENT AND VALIDATION OF A STABILITY-INDICATING HPLC METHOD FOR THE SIMULTANEOUS DETERMINATION OF PAROXETINE HYDROCHLORIDE AND CLONAZEPAM IN PHARMACEUTICAL DOSAGE FORMS
... found to be accurate and precise with good and consistent recoveries at all levels studied. The good % recovery in tablet forms suggests that the excipients present in the dosage forms have no interference in the ...
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STABILITY INDICATING METHOD DEVELOPMENT AND VALIDATION FOR THE SIMULTANEOUS ESTIMATION OF OLMESARTAN, CHLORTHALIDONE AND CILNIDIPINE IN BULK AND PHARMACEUTICAL DOSAGE FORM BY USING RP-HPLC
... the validation and the parameters were within the acceptance criteria like retention times were ...proposed method was successfully applied to routine analysis without any ...
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Development and Validation of Stability Indicating HPLC Method for the Determination of Process and Degradation Related Impurities in Telmisartan Drug Substance
... present method employed C8 column with mobile phase-A consists of ...This method also having LCMS compatibility for impurity ...the method is stability indicating and was thoroughly ...
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Development and validation of a stability indicating RP-HPLC method for Balofloxacin
... For testing linearity seven calibration standards were prepared in the range of 5 to 100 µg/mL (5, 10, 20, 40, 60, 80 and 100 µg/mL). Standard curve was obtained by plotting peak area against concentration and the ...
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DEVELOPMENT AND VALIDATION OF STABILITY INDICATING HPTLC METHOD FOR ALBENDAZOLE
... Linearity was found for ABZ by using standard stock solution 100 µg /ml. To establish linearity, the stock solution was applied on the plate using 100 µl syringe with the help of Linomat V applicator, to give spots of ...
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STABILITY INDICATING ANALYTICAL METHOD DEVELOPMENT AND VALIDATION FOR ESTIMATION OF AZELNIDIPINE
... two method, it can be concluded that spectroscopic method was found to be simple and rapid First order spectroscopic method was found to be more accurate as compared to zero order spectroscopic ...
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DEVELOPMENT AND VALIDATION OF A STABILITY INDICATING RP-HPLC ASSAY METHOD FOR DETERMINATION OF LAMOTRIGINE IN TABLET FORMULATION
... 1 ml of TEA and adjust the pH 6 with OPA, 40:60, v/v) flowing through the column at a constant flow rate of 1.0 ml/ min. The mobile phase was filtered through nylon 0.22 µm membrane filters and was degassed before use ...
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Stability indicating analytical method development and validation for the simultaneous estimation of paracetamol and etodolac using Rp HPLC method in both bulk and pharmaceutical dosage form
... Accuracy was determined by means of recovery experiments, by the determination of % mean recovery of sample at three different levels (50-150%). At each level, three determinations were performed. Percent mean recovery ...
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