Stem cells/cancer cells
Requirement of the transcription factor YB-1 for maintaining the stemness of cancer stem cells and reverting differentiated cancer cells into cancer stem cells
... glioblastoma cells into glio- blastoma stem cells ...of cancer stem cells, leading to the decrease of sphere-forming ability and downregulation of stemness genes of cancer ...
15
Zoledronic acid prevents the tumor-promoting effects of mesenchymal stem cells via MCP-1 dependent recruitment of macrophages
... To further determine the effect of ZA on MSC, MSC were treated with 20 ng/ml ZA for 24 h. ZA significantly inhibited the MCP-1 gene expression in MSC, relative to the untreated MSC (Figure 5). To determine whether ...
11
Application of mesenchymal stem cells for therapeutic agent delivery in anti tumor treatment
... Currently, besides IFN- β there are several other cytokines and tumor-suppressor genes with anticancer activity which are used for genetic modification of MSCs (Table 1). One of the most promising therapeutic ...
10
The novel JNK inhibitor AS602801 inhibits cancer stem cells in vitro and in vivo
... human cancer and an attractive target of cancer therapy ...non-stem) cancer cells and cancer stem cells at a concentration that does not decrease the viability of ...
12
Isolate and identified cancer stem cells by using MCF7 human breast cancer cell line, using mammospheres formation in two different methods
... of cancer will allow scientists to develop an active target therapy of cancer ...many cells that have the ability to rapidly reproduce many more new cells and increase the ...tumour. ...
30
STAT3, stem cells, cancer stem cells and p63
... normal stem cells and are widely used as markers to identify and isolate ...targeted cancer therapies and chemotherapies ...as cancer cells and also because it lacks enzymatic activity, ...
20
Genistein decreases the breast cancer stem-like cell population through Hedgehog pathway
... Cancer stem cells are currently believed to be the root cause of cancer, which contribute to resistance to ther- apy, tumor recurrence, and distant ...the cancer stem cell ...
10
Brca1 breast tumors contain distinct CD44+/CD24 and CD133+cells with cancer stem cell characteristics
... that cancer-initiating cells sorted from established cell lines or primary tumors form sphe- roids when plated in semisolid support or serum-free media supplemented with epidermal grwoth factor and basic ...
16
Cancer Stem Cells In Breast Cancer: A Review
... Cancer stem cells (CSCs) are cancer cells that possess characteristics associated with normal stem cells, specifically the ability to give rise to all cell types found in ...
7
To grab the stroma by the horns: From biology to cancer therapy with mesenchymal stem cells
... the cancer stem cell niche and modulate their function, at least in part via BMP, PGE2, and β-catenin signaling ...MSC-like cells (with differentiation capacity, immunophenotype, and colony formation ...
14
Cancer stem cells in head and neck cancer
... Abstract: Cancer stem cells (CSCs), also called “cells that start the tumor,” represent in themselves one of the most topical and controversial issues in the field of cancer ...Tumor ...
9
Cancer stem cells and angiogenesis
... endothelial cells or other cancer cells in gliomas as shown in ...progenitor cells (EPC), suggesting that CSCs promote local angiogenesis and EPC mo- bilization via stimulating proangiogenic ...
7
Targeting specificity of dendritic cells on breast cancer stem cells: in vitro and in vivo evaluations
... Breast cancer is a leading cause of death in women, and almost all complications are due to chemotherapy ...Drug-resistant cells with stem cell phenotypes are thought to cause failure in breast ...
12
Role of cancer stem cells in hepatocarcinogenesis
... in cancer stem cells (CSCs) among cancer biologists and clinicians, most likely because of their role in the heterogeneity of cancer and their potential application in cancer ...
6
Tumor dormancy in population of cancer stem cells: gene interactions by bioinformatics
... to cancer stem cell genes, two of them leading genes (AKT1 and ...dormant cells, although it is a marker used to identify them (Boixet ...of cancer stem ...breast cancer ...
7
Application prospective of nanoprobes with MRI and FI dual-modality imaging on breast cancer stem cells in tumor
... tate cancer demonstrate that QD probes could accumu- late at tumor sites through passive and active targeting ...of cancer cells under in vivo condi- tions ...Most cancer cells have ...
10
<p>Effect of overexpression of Oct4 and Sox2 genes on the biological and oncological characteristics of gastric cancer cells</p>
... Stem cells can be divided into embryonic and adult stem ...of cancer stem cells (CSCs) was proposed in the last ...that cancer cells can be categorized into many ...
16
CD133 as a Biomarker of Thyroid Cancer Stem Cells
... thyroid cancer (ATC). It has undifferentiated tumor cells that arenot similar to the normal thyroid cells and cannot form the ...tumor cells in ATC might be due to the CD133-expressing in ...
8
Cellular prognostic markers in hepatitis-related hepatocellular carcinoma
... immune cells as prognostic marker for the treatment of CRC ...immune cells within distinct tumor regions, in- cluding tumor interior (TI) and invasive margin (IM), referred to as “Immunoscore”, was ...
5
Cancer stem cell subsets and their relationships
... tumor cells tend to move to their specific distant organs, and differ- ent distant organs tend to accept specific tumor cells ...noma cells into these mice after these transplanted tissue ...melanoma ...
9