Store-operated Ca 2+ -entry (SOCE)
Lithium Sensitive ORAI1 Expression, Store Operated Ca 2+ Entry and Suicidal Death of Neurons in Chorea-Acanthocytosis
... Intracellular Ca 2+ release and store-operated Ca 2+ entry (SOCE) in neurons from healthy volunteers and from ChAc patients without or with lithium ...extracellular ...
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Enhanced Orai1 and STIM1 expression as well as store operated Ca 2+ entry in therapy resistant ovary carcinoma cells
... DISCUSSION The present study disclosed the expression of Orai1 and STIM1 in both, therapy sensitive A2780 and therapy resistant A2780cis ovary carcinoma cells. More importantly, the present observations revealed that ...
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Original Article Enhanced store-operated Ca 2+ entry in high glucose-cultured neonatal and adult diabetic rat cardiomyocytes
... intracellular Ca 2+ homeostasis is a major problem in diabetic ...cardiomyopathy. Store- operated Ca 2+ entry (SOCE) is an important Ca 2+ signalling pathway ...
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Increased store-operated Ca(2+) entry mediated by GNB5 and STIM1
... DISCUSSION GPCR signaling is a well-established pathway by which intra- cellular signals interact with extracellular signals [23]. Coupling Fig. 2. Increased Stim1-Orai1 depen- dent store-operated ...
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Photoactivated fullerene C(60) induces store-operated Ca(2+) entry and cytochrome c release in Jurkat cells
... Fig. 2. dynamics of store-operated Ca 2+ entry in control Jurkat cells (1) and at 1 h (2) or 3 h (3) after fullerene ...
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Activation of store – operated Ca(2+) entry in cisplatin resistant leukemic cells after treatment with photoexcited fullerene C(60) and cisplatin
... librium level in L1210 and L1210R was 3.5 and 2 times lower (Fig. 3), while the size of SOCE was 2.2 and 1.8 times higher than in control, respectively (Fig. 4). As it was previously shown, photoexcitation of ...
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Nanomolar potency and selectivity of a Ca 2+ release-activated Ca 2+ channel inhibitor against store-operated Ca 2+ entry and migration of vascular smooth muscle cells
... ATP-evoked Ca 2+ entry in human saphenous vein VSMCs and that this mechanism potentiates migration of the cells but is not essential for ...physiological Ca 2+ ...the Ca ...
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STIM and Orai1 Variants in Store-Operated Calcium Entry
... Spain, 2 Department of Medical Physiology and Biophysic, Institute of Biomedicine of Seville, Virgen del Rocio University Hospital, Consejo Superior de Investigaciones Científicas, University of Seville, Sevilla, ...
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Blockage of store-operated Ca<sup>2+</sup> entry antagonizes Epstein–Barr virus-promoted angiogenesis by inhibiting Ca<sup>2+</sup> signaling-regulated VEGF production in nasopharyngeal carcinoma
... of store-operated Ca 2+ entry (SOCE) suppressed epidermal growth factor (EGF)-stimulated cell migration and eliminated the extrava- sation event from the vasculature in NPC ...
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RPGR protein complex regulates proteasome activity and mediates store-operated calcium entry
... reticulum Ca 2+ - ATPases, showed impaired store-operated Ca 2+ entry (SOCE), which is mediated by STIM1 and Orai1 ...ER store depletion in RPGR, RPGRIP1 or ...
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Inhibition of store-operated calcium entry in microglia by helminth factors: implications for immune suppression in neurocysticercosis
... of Ca 2+ from intracellular endoplasmic reticulum (ER) stores, followed by subsequent store-operated Ca 2+ entry (SOCE) across the plasma membrane (PM) ...Such Ca ...
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Store-operated Ca2+ entry regulates glioma cell migration and invasion via modulation of Pyk2 phosphorylation
... messenger Ca 2+ plays an important role in many fundamental physio- logical processes, including cell excitability, exocytosis, motility, apoptosis, and transcription ...that Ca 2+ also ...
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Store-operated Ca2+ entry in proliferating and retinoic acid-differentiated N- and S-type neuroblastoma cells
... Bcl-2. Store-operated Ca 2+ entry (SOCE) was then measured in proliferating and differentiated N- and S-type cell populations and the expression of STIM1, Orai1 and TRPC1, three ...
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Store-operated calcium entry in human spermatozoa
... [Ca 2+ ] i response induced by bolus progesterone application, which is believed to be regulated by ...intracellular Ca 2+ stores where they may form part of the SOCE ...intracellular ...
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Activation of ERK1/2 by Store-Operated Calcium Entry in Rat Parotid Acinar Cells
... of Ca 2+ elevation by Ca 2+ entry that we investigated, SOCE was unique in its stimulation of ERK1/2 activation in rat parotid acinar ...cells. Ca 2+ ionophores and ...
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Molecular composition and pharmacology of store-operated calcium entry in sensory neurons
... other Ca 2+ handling proteins such as TRPM4 channels (Takezawa et ...membrane Ca 2+ channels, this may contribute to a depolarization and a reduced Ca 2+ entry through ...
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Store-operated Ca2+ entry controls ameloblast cell function and enamel development
... SEM and EDAX. BSE-SEM was performed as previously described (16, 41). Briefly, mandibles of 6- to 8-week-old WT and Stim1/2 K14cre mice were extracted and cleaned of soft tissues. Following graded dehydra- tion to ...
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The role of the Sigma1 receptor (σ1R) in Store-operated calcium entry (SOCE) microdomains
... Precast NuPAGE Bis-Tris gels (Invitrogen, 4-12%) and 1XMES buffer (Thermo Fisher) were used for protein electrophoresis to separate proteins based on their size. The wells were loaded with 40µl of total volume for each ...
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Phenotype-specific store-operated calcium entry and the differentiation response in neuroblastoma cells /
... a Ca 2+ sensor that alters the gating of SOCs at the PM to allow Ca 2+ entry for replenishment of depleted Ca 2+ stores (Liou 2005; Roos ...EF-hand Ca 2+ ...
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Store-operated calcium entry in neural cells. A role in Charcot-Marie-Tooth disease
... used Ca 2+ addback protocol to study SOCE, in which neuronal stores are emptied in a Ca 2+ -free medium, and then Ca 2+ is added to the external ...multiple Ca 2+ ...
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