Stress-induced cell death
Human Cytomegalovirus Protein pUL38 Induces ATF4 Expression, Inhibits Persistent JNK Phosphorylation, and Suppresses Endoplasmic Reticulum Stress-Induced Cell Death
... ER stress-in- duced cell ...extrinsic cell death pathway but protected cells from the treat- ment of thapsigargin, an agent that causes ER stress by desta- bilizing intracellular ...
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Stress-Induced Cell Death Is Mediated by Ceramide Synthesis in Neurospora crassa
... sphingosine, rather than to phytosphingosine. This uniqueness may render the induced phytoceramide an ideal signaling mol- ecule. Its formation may depend upon and reflect the inhibi- tion of pathway enzymes due ...
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PROSOPIS CINERARIA LEAF EXTRACT PROTECT H2O2 INDUCED OXIDATIVE STRESS INDUCED CELL DEATH IN SACCHAROMYCES CEREVISIAE
... Oxidative stress is an imbalance between pro-oxidants and antioxidants in the body, and oxidative stress is a complex process ...environmental stress and cell dysfunction, ROS levels increase ...
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miRNA signature of unfolded protein response in H9c2 rat cardiomyoblasts
... ER stress, in a PERK-dependent manner, and contributes to optimum induction of Bim and ER stress-induced cell death ...ER stress conditions) and different models of cardiac ...
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Neuroprotective effect of a new DJ-1-binding compound against neurodegeneration in Parkinson's disease and stroke model rats
... be induced at least by oxidative ...therapy, cell death progresses during ...oxidative stress-induced cell death are therefore necessary for fundamental therapies for PD ...
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Neuroprotective effects of Peltophorum pterocarpum leaf extract against hydrogen peroxide induced oxidative stress and cytotoxicity
... Oxidative stress due to the over production of reactive oxygen species (ROS) during normal aerobic respiration in the neurons play an important role in the pathophysi- ology of many neurodegeneration ...nally ...
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Original Article Role of Bcl-xL Induction in HGF-mediated Renal Epithelial Cell Survival after Oxidant Stress
... epithelial cell survival by dual mechanisms involving Bad phosphorylation and Bcl-xL ...from death induced by oxidant stress both in vitro and in ...oxidant stress-induced ...
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Alterations in Energy/Redox Metabolism Induced by Mitochondrial and Environmental Toxins: A Specific Role for Glucose-6-Phosphate-Dehydrogenase and the Pentose Phosphate Pathway in Paraquat Toxicity
... oxidative stress-induced cell ...toxicity induced by G6PD over- expression and the protective e ff ects of 6-AN can be explained by the requirement of reducing equivalents for paraquat to redox ...
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Ceramide activates lysosomal cathepsin B and cathepsin D to attenuate autophagy and induces ER stress to suppress myeloid- derived suppressor cells
... general cell death or survival regulators in various types of cells ...of cell death is enhancement of death receptor clustering to increase extrinsic apoptosis ...tumor cell ...
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Chelerythrine induced cell death through ROS-dependent ER stress in human prostate cancer cells
... Notes: cells were treated with che (10 μM) for 24 h in the presence or absence of prior 1 h incubation with nac (10 mM). (A, B) Flow cytometry analysis of cell apoptosis using Annexin V-FITC+Pi staining as ...
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Progress and perspectives on the role of RPE cell inflammatory responses in the development of age-related macular degeneration
... RPE cell death (Zhang et al ...RPE cell apoptosis induced by A2E, a byproduct of phototransduction (Mukherjee et al 2007), as well as hydrogen peroxide and tumor necrosis factor- α (Mukherjee ...
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Targeting Rb Mutant Cancers by Inactivating TSC2
... induces cell death as overexpression of activated Akt failed to inhibit cell death in Rb, TSC2 inactivated cells ...undergoing cell death induced by a variety of ...
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Clofoctol and sorafenib inhibit prostate cancer growth via synergistic induction of endoplasmic reticulum stress and UPR pathways
... PC-3 cell death through the synergistic induction of ER ...synergistically induced ER stress by the combi- nation of sorafenib and clofoctol by qPCR and Western ...ER stress between ...
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Ototoxin-induced cellular damage in neuromasts disrupts lateral line function in larval zebrafish
... Acute copper exposure induces oxidative stress and cell death in lateral line hair cells of zebrafish larvae.. Cisplatin-induced hair cell loss in zebrafish Danio rerio lateral line.[r] ...
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GSK-3β-mediated regulation of cadmium-induced cell death and survival
... ER stress, Ca 2+ was measured over time via flow cytometry using the calcium indicator dye fluo-4 ...ER stress, the GRP78 protein level was assessed in cells pretreated with ...
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Stretch induced programmed myocyte cell death
... programmed cell death, and the alterations in active and passive tensions with time of overloaded papillary ...oxidant stress, expression of Fas, programmed cell death, architectural ...
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Anti EGFL7 antibodies enhance stress induced endothelial cell death and anti VEGF efficacy
... from stress-induced ...non–small cell lung cancer, we found that anti-EGFL7 enhanced both the progression-free and overall survival benefits derived from anti-VEGF therapy in a dose-dependent ...
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Overexpression of selenoprotein H prevents mitochondrial dynamic imbalance induced by glutamate exposure
... in cell death both in vitro and in ...induces cell death by mechanisms that involve well defined, receptor-initiated excitotoxicity and non-receptor mediated oxidative toxicity pathways ...
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Tat-HSP22 inhibits oxidative stress-induced hippocampal neuronal cell death by regulation of the mitochondrial pathway
... cardiac cell survival and HSP22 has protective effects in the stress condition of cardiac cells via regulating the PI3K/Akt pathways ...oxidative stress and longevity in flies whereas the ab- sence ...
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Synergistic effects of amyloid peptides and lead on human neuroblastoma cells
... neuronal death is still ...Oxidative stress, which plays an important role in Aβ-mediated neuronal cytotoxicity by triggering or facilitating neuro-degeneration through a wide range of molecular events, ...
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