Suppression of cell proliferation
Influences of surface coatings and components of FePt nanoparticles on the suppression of glioma cell proliferation
... g/mL, cell proliferation was decreased to approximately ...Significant suppression of cell proliferation by FePt-Cys NPs was observed at exposed doses higher than 25 µ ...E, cell ...
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CELF1 is Up-Regulated in Glioma and Promotes Glioma Cell Proliferation by Suppression of CDKN1B
... U87 cell lines, and a normal astroglial cell line, i.e. 1800 cell line, were used in our ...glioma cell lines, whereas low expression was found in the normal astroglial cell line ...
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Suppression of renal cell proliferation, induction of apoptosis and cell cycle arrest: Cytotoxicity of vanadium in broilers
... Detection of DNA fragments in situ using the terminal deoxyribonucleotidyl transferase(TDT)-mediated dUTP- digoxigenin nick end labeling (TUNEL) assay is increas- ingly applied to investigate cell apoptosis. At 42 ...
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Knockdown of SETDB1 inhibits breast cancer progression by miR-381-3p-related regulation
... of cell proliferation, cell cycle progression and migration, ...and cell lines, and SETDB1 depletion led to a suppression of cell proliferation, cell cycle ...
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Dual targeting of retinoid X receptor and histone deacetylase with DW22 as a novel antitumor approach
... mediated suppression of cell proliferation, migration, invasion, tube formation, and –induced cell differentiation and ...both cell lines were attenuated by silence of RXRα, whereas ...
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Ciclopirox inhibits cancer cell proliferation by suppression of Cdc25A
... levels of cyclins D1/E and CDK4 [7]. Since Cdc25A is a positive regulator for G 1 -CDKs [22, 23], we speculated that 5 μM of CPX may induce the G 1 arrest of the cells by decreasing Cdc25A level. To this end, MDA-MB-231 ...
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SAE1 promotes human glioma progression through activating AKT SUMOylation-mediated signaling pathways
... block cell endogenous SAE1 level to observe cell growth and ...decreased cell proliferation by 19, 29% in U87 and U251 cells by 100 nM siSAE1–3 treatment for 60 h (p < ...Meanwhile, ...
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Hippuric acid nanocomposite enhances doxorubicin and oxaliplatin-induced cytotoxicity in MDA-MB231, MCF-7 and Caco2 cell lines
... induced suppression of cell proliferation for the MCF-7, MDA-MB231, and Caco2 cell lines, as compared to free hippuric acid and free doxorubicin and oxaliplatin, which did not exhibit the same ...
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Anti-cancer effects of ginsenoside compound k on pediatric acute myeloid leukemia cells
... both cell lines. We then assessed the effect of compound K on Kasumi-1 cell proliferation as determined by DNA synthesis using the Cell Proliferation ELISA BrdU ...this ...
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Chromatin remodeling gene ARID2 targets cyclin D1 and cyclin E1 to suppress hepatoma cell progression
... suppress cell proliferation and tumor growth in mice, whereas ARID2 knockdown contributed to the enhancement of cellular proliferation and ...tumorigenicity. Suppression of ARID2 expression ...
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Selective suppression of insulin induced proliferation of cultured human hepatoma cells by somatostatin
... Hep3B. Results showed that both insulin and T3 can stimulate cell growth of serum starved Hep3B cells at physiological concentrations. SRIF alone showed little growth-promoting activity. When added concurrently ...
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<p>Effect of <em>SMYD3</em> on biological behavior and H3K4 methylation in bladder cancer</p>
... T24 cell proliferation and colony for- mation. Proliferation and colony formation are important fac- tors for cancer cell ...T24 cell proliferation and colony formation were ...
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Volume 7 | Issue 3 - 2017
... of proliferation in cancer cells is an essential criterion for an anticancer ...inhibited cell proliferation through the induction of ...of cell proliferation is mediated by the ...
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<p>miR-373 promotes neuroblastoma cell proliferation, migration, and invasion by targeting SRCIN1</p>
... and suppression of SRCIN1 by miR-150 was found to be a cause of lung cancer cell growth and ...promotes cell proliferation, migration and invasion in vitro, and tumor growth in ...cancer ...
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Inhibition of arginase by CB-1158 blocks myeloid cell-mediated immune suppression in the tumor microenvironment
... T cell activity in co-culture, and importantly, T cell proliferation can be restored either by restoring ar- ginine to the media or by the addition of an arginase in- hibitor, showing that arginase ...
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Original Article Overexpression of IL-12 reverses the phenotype and function of M2 macrophages to M1 macrophages
... and cell surface antigens were ...the cell surface anti- gens CD86, a marker of M1 macrophages [29], was up-expressed, whereas M2 macrophages marker CD206 [30] showed a down-expres- ...HepG2 cell ...
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Potential Mechanisms of Action of Curcumin for Cancer Prevention: Focus on Cellular Signaling Pathways and miRNAs
... the proliferation of GC cells [85]. Curcumin also promoted GC cell apoptosis by activating caspase-3/9 and decreasing the Bcl-2/Bax ...GC cell autophagy by inducing conversion of ...
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New frontiers in oncolytic viruses: optimizing and selecting for virus strains with improved efficacy
... In summary, oncolytic viruses, based on engineered vec- tors or naturally occurring strains, have proven efficient in various preclinical tumor models providing suppression of tumor growth, tumor regression, and ...
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Discovery and evaluation of ZT55, a novel highly-selective tyrosine kinase inhibitor of JAK2V617F against myeloproliferative neoplasms
... driving cell survival and proliferation independently from signals triggered by cytokine binding ...promote cell growth in numerous of myeloid leukemia and solid tumors ...tumor cell ...
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CD117+CD44+ Stem T Cells Develop in the Thymus and Potently Suppress T-cell Proliferation by Modulating the CTLA-4 Pathway
... Flow cytometry can be used to characterize single cells in an efficient and expedient manner [25], and can be used to describe DN cells which are present in limited amounts in the mouse thymus. Previously, a highly re- ...
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