synthetic analogs
Potential applications of curcumin and its novel synthetic analogs and nanotechnology-based formulations in cancer prevention and therapy
... several synthetic analogs of curcumin have been designed and shown to exhibit a greater metabolic stabi- lity and biological activity than those of curcumin itself and are without increased toxicity (Figure ...
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Anti Inflammatory Activity of Choisya ternata Kunth Essential Oil, Ternanthranin, and Its Two Synthetic Analogs (Methyl and Propyl N Methylanthranilates)
... Based on the observed effects of EO, we further evaluated the anti-inflammatory effects of ternanthranin, as well as of the two new synthetic analogs, methyl and propyl N-methylanthra- nilates. To discard a ...
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Original Article Screening flavonoids and their synthetic analogs to target liver cancer stem-like cells
... and synthetic analogues on parental cells and ...and synthetic analogues (curcumin, casticin, luteolin and 8-bromo-7-me- thoxy chrysin (BrMC)) resulted in greater survival and self-renewal inhibitory ...
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Specific inhibition by synthetic analogs of pyruvate reveals that the pyruvate dehydrogenase reaction is essential for metabolism and viability of glioblastoma cells
... into cells (SLC16A1) and mitochondria (MPC1+MPC2) are expressed proportionally to the PDH subunits (PDHA1+PDHB), suggesting expression to be a measure of the physiologically linked processes of pyruvate influx and ...
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Emerging role of Garcinol, the antioxidant chalcone from Garcinia indica Choisy and its synthetic analogs
... Our preliminary results (unpublished data) suggest an anti-cancer activity of garcinol against human cancer cell lines through induc- tion of apoptosis, and inhibition of NF- κ B-DNA bin[r] ...
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Rescue of synthetic analogs of genomic RNA and replicative-intermediate RNA of human parainfluenza virus type 3.
... Transfection of PIV3-infected cells with the synthetic negative-sense RNA resulted in rescue of the PIV3-CAT vRNA analog, as demonstrated by expression of CAT and the production of an in[r] ...
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Synthetic Analogs of Green Tea Polyphenols as Proteasome Inhibitors
... The synthetic and the commercial ( )-GCG gave identical proteasome-inhibitory prop- erties and therefore only the commercial ( )-GCG was used in the experiments presented in this ...
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Synthesis and Determination of Antitumor Activity of Jacaranone and Synthetic Analogs
... Apoptotic, necrotic and viable cells were quantified using an Annexin V and propidium iodide labeling kit (Dead Cell Apoptosis Kit with Annexin V Alexa Fluor™ 488 & Propidium Iodide (PI), Molecular Probes®). Briefly ...
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Synthesis and Biological Evaluation of 4-Oxazolidinones and Dual JAK/TRPV-1 Inhibitors.
... lipoxazolidinone analogs designed to probe the interactions of these molecules with their biological environment is ...their synthetic analogs were found to have potent antimicrobial activity against ...
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Conservation of determinants for class II-restricted T cells within site E of influenza virus hemagglutinin and factors influencing their expression.
... Three distinct clones directed towards the sequence LIDALLGDP were remarkably similar in their pattern of response to a set of synthetic analogs of the determinant, suggesting that resid[r] ...
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Spice, Bath Salts, and Behavioral Health
... are synthetic versions of controlled substances that are produced to avoid existing drug ...salts analogs to its list of Schedule I substances. There are many synthetic chemicals that can be used to ...
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Analogs of the novel phytohormone, strigolactone, trigger apoptosis and synergize with PARP inhibitors by inducing DNA damage and inhibiting DNA repair
... molecules, synthetic analogs of SLs, induce G2/M arrest and apoptosis in a variety of human cancer cells, but have minimal influence on growth and viability of non- transformed human fibroblasts, mammary ...
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Generalizations and Analogs of the Frattini Subalgebra.
... algebra analogs to the group results of Kappe and Kirtland in ...our analogs are nilpotent, and find contain- ments relations and a characterization of ...
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Observing strategies for the detection of Jupiter analogs
... Regardless of their role in ensuring (or threatening) the habitability of telluric worlds, the search for Jupiter-analogs will provide a key datum for models of planetary formation and evolution - attempting to ...
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The Generalizations of Hilbert's Inequality
... He, “On further analogs of Hilbert’s inequality,” International Journal of Mathematics and Mathematical Sciences, vol.[r] ...
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Bridged Nucleic Acids Reloaded
... progress in nucleic acids research, led to the design of nucleotide analogs that when.. 26.[r] ...
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On Further Analogs of Hilbert's Inequality
... Yongjin Li: Institute of Logic and Cognition, Department of Mathematics, Sun Yat-Sen University, Guangzhou 510275, China Email address: stslyj@mail.sysu.edu.cn You Qian: Department of Ma[r] ...
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Antifibrotic vitamin D analogs
... of synthetic ligands of the vitamin D receptor that target the TGF-b–SMAD signaling pathway, which is known to regulate fibrosis-associated gene expression, without inducing VDR-associated ...
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cocaine analogs clarke pdf
... dosage as described by Luduena and Hoppe.16 In the mouse heart norepinephrine uptake inhibition experiments, aqueous solutions of DMI and cocaine hydrochlorides were used, as was an aque[r] ...
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Modulation of nicotinamide adenine dinucleotide and poly(adenosine diphosphoribose) metabolism by the synthetic "C" nucleoside analogs, tiazofurin and selenazofurin A new strategy for cancer chemotherapy
... the analogs interfere with NAD synthesis, apparently by blocking formation of nicotinamide ...The analogs also serve as weak inhibitors of poly(ADP-ribose) polymerase, which is an NAD-utilizing, ...
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