System of Metoprolol Tartrate
Design and in Vitro Evaluation of Transdermal Drug Delivery System of Metoprolol Tartrate
... Metoprolol tartrate is a beta adrenoreceptor blocking agent used in the treatment of cardiovascular ...using metoprolol tartarate orally may result in poor patient compliance because of low ...
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DESIGN, FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE PULSATILE CAPSULE OF METOPROLOL TARTRATE
... CONCLUSION: The results all the way suggest that lag time is dependent on the nature of the materials employed in plug preparation and found that position of the plug in the capsule body significantly affects lag time. ...
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PHARMACEUTICAL EVALUATION OF DIFFERENT SUPER DISINTEGRANTS IN DESIGN OF METOPROLOL TARTRATE ORODISPERSIBLE TABLETS
... Metoprololtartarate is a cardio selective beta-1 adrenoreceptor blocker mostly used in the treatment of acute disorders such as angina pectoris and hypertension. It is a BCS (Biopharmaceutical Classification ...
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Analytical study of UV Spectrophotometric and HPLC methods for simultaneously determination of metoprolol and hudrochlorothiazide in fixeddosage combinations
... for Metoprolol tartrate and Hydrochlorothiazide - substance mixtures and in drug preparations with fixed doses are for identification, purity and assay ...about system suitability test (better ...
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Chemical stability indicating HPLC study of fixed dosage combination containing metoprolol tartrate and hydrochlorothiazide
... cardiovascular system, especially hypertension. The active substance metoprolol is employed either as metoprolol succinate or metoprolol tartrate (where 100 mg metoprolol ...
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EFFECT OF POLYMER RATIO AND EXCIPIENTS ON METOPROLOL TARTRATE RELEASE FROM CHITOSAN – SODIUM ALGINATE POLYMERIC IMPLANTS
... implantable system of the drug metoprolol tartrate because it plays an important role in the treatment of high blood pressure, strokes, heart attacks and ...of metoprolol tartrate with ...
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COMPARISON OF DIFFERENT SUPERDISINTEGRANTS IN DESIGNING OF FAST DISSOLVING TABLETS OF METOPROLOL TARTRATE
... DSC studies: DSC scan of about 5mg accurately weighed MT and tablet mixtures were performed by using an automatic thermal analyzer system (DSC60, Shimadzu Corporation, Japan). Sealed and perforated aluminium pans ...
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Analytical Method for the Simultaneous Estimation of Hydrochlorothiazide and Metoprolol Tartrate using RP HPLC
... powder, and weighed quantity of powder equal to half of the average weight, in each of the three 100 ml volumetric flasks. Then 50 ml of methanol was added in each of the volumetric flasks. The contents of the flask were ...
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DEVELOPMENT AND EVALUATION OF ORALLY DISINTEGRATING TABLETS OF METOPROLOL TARTRATE BY DIRECT COMPRESSION METHOD USING DIFFERENT DILUENTS
... delivery system aims to provide rational drug therapy by enhanced safety and efficacy of drug molecule by formulating convenient dosage form to administration 2 ...
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Formulation and In-Vitro Evaluation of Metoprolol Tartrate Microspheres by using Natural Semisynthetic and Synthetic Polymers as Controlled Release Dosage Form
... 21) Sunit kumar sahoo., et al. (2005) Microspheres were prepared by solvent evaporation method using an acetone / liquid paraffin system. Magnesium stearate . The prepared microspheres were characterized for their ...
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In situ gel of metoprolol tartrate: Physicochemical characterization, In vitro diffusion and histological studies
... and F13 (0.9942) was maximum for Higuchi, showing mixed order kinetics while n value obtained on treatment with Korsemayer Pappas equation were near to 0.5, suggesting release by fickian diffusion mechanism. The nasal ...
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MONTMORILLONITE USED AS AN EXTENDED RELEASE DELIVERY VEHICLE AND INCREASE BIOAVAILABILITY FOR METOPROLOL TARTRATE: AN ANTIHYPERTENSIVE DRUG
... The aim of the present work Montmorillonite (Mt) based drug delivery system has been explored for the extended release of an antihypertensive drug Metoprolol tartrate (MPT). Employing the batch ...
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Formulation Development And In-Vitro/Ex-Vivo Evaluation Of Novel Buccoadhesive Films Of Metoprolol Tartrate Using 23 Factorial Design Techniques
... delivery system to be placed at different sites on the same membrane on different ...delivery system or other excipients include in the formulation reversibly damage or irritate the ...
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Simultaneous estimation of metoprolol tartrate and chlorthalidone by using RP HPLC and method development as per ICH guidelines
... a system suitability test was ...HPLC system. For analysis of marketed samples, twenty tablets of metoprolol tartrate each containing 3TC (300 mg) and chlorthalidone (600mg) were weighed and ...
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FORMULATION AND CHARACTERIZATION OF MATRIX AND TRIPLE-LAYER MATRIX TABLETS FOR CONTROLLED DELIVERY OF METOPROLOL TARTRATE
... disorders and prophylaxis of migraine. It has been classified as a class I substance according to the bio pharmaceutics classification system (BCS), that it is highly soluble and highly permeable having pKa value ...
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Sublingual fast dissolving niosomal films for enhanced bioavailability and prolonged effect of metoprolol tartrate
... delivery system to enhance the bioavailability and prolong the therapeutic effect of MT, thus improving the patient compliance by eliminating the need for frequent dosing of the ...
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DESIGN AND IN VITRO CHARACTERIZATION OF GASTRO-RETENTIVE BILAYER FLOATING TABLET OF METOPROLOL TARTRATE
... It is clear from the figures that the formulations showed biphasic release of MT. In the first phase, the first fraction of the dose (immediate release layer) was released in less than 30 min, because of prompt ...
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FORMULATION AND EVALUATION OF FAST DISSOLVING ORAL FILMS OF METOPROLOL TARTRATE
... Oral film includes various ingredients for its formulation which includes polymers, active pharmaceutical ingredient, and film stabilizing agents, sweeteners, flavors, colors, saliva stimulating agents, preservatives, ...
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INFLUENCE OF INCREASING CONCENTRATIONS OF MAGNESIUM STEARATE AND TALCUM ON DISSOLUTION PROFILE AND PHYSICAL PARAMETERS OF METOPROLOL TARTRATE EXTENDED RELEASE MATRIX TABLETS
... delivery system was applied to investigate release pattern of drug from all ...of metoprolol tartrate from matrix tablets containing varying ratios of MS and T is different as given in Figures 1, 2 ...
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Permeation studies of atenolol and metoprolol tartrate from three different polymer matrices for transdermal delivery
... Transdermal delivery constitutes one of the most important routes for new drug delivery system (NDDS). Transdermal delivery of drugs offers several advantages over conventional delivery methods including oral and ...
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