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Systemic immune

Prevention of Hearing Loss by Alteration of the Systemic Immune System

Prevention of Hearing Loss by Alteration of the Systemic Immune System

... the systemic immune system constituted by bone marrow cells ...with systemic autoimmune diseases including not only SLE, but also RA [28] [29] [30], ulcerative colitis [31] [32], relapsing polychon- ...

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High systemic immune–inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma

<p>High systemic immune&ndash;inflammation index represents an unfavorable prognosis of malignant pleural mesothelioma</p>

... 2,16–19 Systemic immune – -in fl ammation index (SII) (SII=N×P/L), known as systemic immune – in fl ammation index, which is calculated on neutrophil (N), platelet (P) and lymphocyte (L) counts, ...

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Oxaliplatin Treatment Alters Systemic Immune Responses

Oxaliplatin Treatment Alters Systemic Immune Responses

... on systemic immune responses remain largely ...cause systemic immunosuppression and, instead, has the capacity to induce beneficial antitumor immune ...

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Systemic immune-inflammation index and ultrasonographic classification of breast imaging-reporting and data system predict outcomes of triple-negative breast cancer

<p>Systemic immune-inflammation index and ultrasonographic classification of breast imaging-reporting and data system predict outcomes of triple-negative breast cancer</p>

... diseases, immune dis- eases, coronary artery diseases, and hematological diseases; suffering from an infectious disease within 2 weeks of enroll- ment; using anti-inflammatory or immunosuppressive drugs prior to ...

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Prevention of Hearing Loss by Alteration of the Systemic Immune System

Prevention of Hearing Loss by Alteration of the Systemic Immune System

... the immune system, that contributes to the aging process and the development of age-related disabilities and diseases including age-related SHL ...overall systemic response and can induce cochlear ...

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Local and Systemic Immune and Inflammatory Responses to Helicobacter pylori Strains

Local and Systemic Immune and Inflammatory Responses to Helicobacter pylori Strains

... Colonization with Helicobacter pylori eventuates in varied clinical outcomes, which relate to both bacterial and host factors. Here we examine the relationships between cagA status, serum and gastric juice antibody ...

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Preoperative systemic immune-inflammation index predicts prognosis of patients with non-metastatic renal cell carcinoma: a propensity score-matched analysis

Preoperative systemic immune-inflammation index predicts prognosis of patients with non-metastatic renal cell carcinoma: a propensity score-matched analysis

... decades. Immune cells play an essential role in the inflammatory process leading to the production of cytokines and chemokines that promote tumor development, invasion and metasta- sis ...between immune ...

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Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide

Plasminogen mediates communication between the peripheral and central immune systems during systemic immune challenge with lipopolysaccharide

... Plasminogen (PLG) and its active form, serine pro- tease plasmin, are blood proteins that play roles in fi- brinolysis, wound healing, cell signaling, extracellular matrix degradation, and inflammatory regulation [6]. ...

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Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

Systemic immune-inflammation index predicts the clinical outcome in patients with metastatic renal cell cancer treated with sunitinib

... analysis, and the sample size, however for the first time we demonstrated that SII at baseline and its changes at week 6 are independent predictive and prognostic factors for these RCC patients underwent first-line ...

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Vol 68, No 2 (2016)

Vol 68, No 2 (2016)

... enhanced systemic immune effects, which include lymphocyte proliferation and phagocytosis of macrophages can be attributed to the enhancement of Th1-type immune activity, since the Th1-type cy- ...

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Prognostic value of inflammation-based prognostic index in patients with nasopharyngeal carcinoma: a propensity score matching study

Prognostic value of inflammation-based prognostic index in patients with nasopharyngeal carcinoma: a propensity score matching study

... (PNI), systemic immune-inflammation index (SII), and their combination in nasopharyngeal carcinoma (NPC) patients receiving intensity-modulated radiotherapy ...

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An IMD-like pathway mediates both endosymbiont control and host immunity in the cereal weevil Sitophilus spp.

An IMD-like pathway mediates both endosymbiont control and host immunity in the cereal weevil Sitophilus spp.

... endosymbiotic associations, host-symbiont coevolution is accompanied by a bacterial genomic erosion that generally results in the loss of bacterial genes that are redundant or harmful for the association [8, 9, 11]. ...

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Adjuvants : an essential component of neisseria vaccines

Adjuvants : an essential component of neisseria vaccines

... systemic immune responses. However, these studies did not evaluate mucosal immune responses ...mucosal immune responses than parenteral administration ...high immune responses at the ...

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Anti–PD 1/PD L1 therapy of human cancer: past, present, and future

Anti–PD 1/PD L1 therapy of human cancer: past, present, and future

... of immune responses during anti-PD therapy indicate that selective expan- sion and functional enhancement of T cells occur at the tumor site, while activity of immune cells in the bloodstream fails to ...

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Weighing up the pros and cons of immune checkpoint inhibitors in the treatment of melanoma.

Weighing up the pros and cons of immune checkpoint inhibitors in the treatment of melanoma.

... The advent of monoclonal antibodies functioning as immune checkpoint inhibitors has changed the way advanced melanoma is treated. CTLA-4 inhibitors such as ipilimumab and the PD-1 inhibitors pembrolizumab and ...

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Induction of systemic and mucosal immunity against methicillin-resistant Staphylococcus aureus infection by a novel nanoemulsion adjuvant vaccine

Induction of systemic and mucosal immunity against methicillin-resistant <em>Staphylococcus aureus</em> infection by a novel nanoemulsion adjuvant vaccine

... intramuscular systemic and nasal mucosal immune responses demonstrated that this nanoemulsion vaccine could improve the specific immune responses of immunoglobulin (Ig)G and related subclasses, such ...

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Serum and Mucosal Immune Responses to an Inactivated Influenza Virus Vaccine Induced by Epidermal Powder Immunization

Serum and Mucosal Immune Responses to an Inactivated Influenza Virus Vaccine Induced by Epidermal Powder Immunization

... Antigen-specific IgA-secreting cells in mucosal tissue. A new experiment was performed to enumerate PR8-specific IgA-secreting cells in mucosal tissues of mice receiving EPI. In this study, two groups of mice (n ⫽ 8) ...

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Local and systemic innate immune response to secondary human peritonitis

Local and systemic innate immune response to secondary human peritonitis

... acute systemic and peritoneal innate immune response with a simultaneous release of pro and anti-inflammatory ...innate immune response in ...

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Durvalumab-induced diabetic ketoacidosis followed by hypothyroidism

Durvalumab-induced diabetic ketoacidosis followed by hypothyroidism

... The association between development of an irAE and oncological response remains controversial. Horvat et al. found that overall survival and time to treatment failure in melanoma patients treated with ipilimumab were not ...

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Renal involvement in autoimmune connective tissue diseases

Renal involvement in autoimmune connective tissue diseases

... Alterations of kidney function in Sjögren syndrome, systemic scleroderma (SSc), auto-immune myopathies (dermatomyositis and polymyositis), systemic lupus erythematosus (SLE), antiphospho[r] ...

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