T cells
CD4+ T Cells Develop Antiretroviral Cytotoxic Activity in the Absence of Regulatory T Cells and CD8+ T Cells
... ⫹ T cells are es- sential in controlling FV infection ...target cells is critical for retroviral immu- ...⫹ T cells during acute FV infection results mainly in reduced antibody ...
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Vγ9Vδ2 T Cells in Human Legionellosis
... 2 T cells, implying that the subset may also be pathophysiologically important in a mild and transient form of intracellular bacterial ...2 T cells. Possibly, V ␥ 9V ␦ 2 T cells ...
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Survivin specific T cell receptor targets tumor but not T cells
... (P < 0.0001; Supplemental Figure 5). Structural models of the TCRs were generated using Rosetta soft- ware (13–15) and were docked onto models of the HLA-survivin pep- tide complex to predict the optimal bound ...
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Langerhans cells protect from allergic contact dermatitis in mice by tolerizing CD8+ T cells and activating Foxp3+ regulatory T cells
... epidermal T cells (DETC), which were only pres- ent in the high-density fraction (Supplemental Figure ...+ T cells (Figure 5E), demonstrating that LCs but not ...
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mTOR inhibitors effects on regulatory T cells and on dendritic cells
... scenario, T cell immunoregu- lation has been defined as the hallmark of peripheral ...regulatory T cells (Tregs) and dendritic cells ...Dendritic cells, Operational tolerance, ...
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γδ T Cells and Their Potential for Immunotherapy
... γδ T cells can recognize MHC molecules such as group 1(CD1a, b, c) and group 2 (CD1d) CD1 mole- cules [43, ...γδ T cells, and do not need Ag processing ...(CMV)–infected cells by γδ ...
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T cells in atopic eye disease
... T cells expressing mRNA for IL-3, IL-4 and IL-5 in the absence of IL-2 mRNA may be present, representing Th2-like ...coexpressing T cells in AKC may represent Th2-like cells, since some ...
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Targetless T cells in cancer immunotherapy
... of T cells among PBMC or TIL, or global mutational load of the cancer cells, just to mention a ...cancer cells, the microenvironment, or the immune system have shown correlation with response ...
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Clonal analysis of CD4+ T cells
... f T cells occurs in lymphoid organs including the lymph nodes, spleen and mucosal associated lymphoid tissue, where antigen presenting cells come into contact with naïve T cells in ...
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T cells and reactive oxygen species
... primary T cells is incubation with antioxidants. In murine T cells, butylated hydroxyanisole (BHA) blocks DNA synthesis and CD25 expression [73], whereas the mitochondria-targeted vitamin E ...
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Regulatory T cells in rheumatoid arthritis
... responder T cells, thereby ‘compensating’ for the enhanced regulatory capacity of the synovial Tregs ...of T effector cells to the suppressive effects of Tregs ...neighboring T ...
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Cytotoxic T cells and viral hepatitis
... The T cell response to HBV is strong and broadly specific in acutely infected patients (1), and these T cells typically secrete type 1 antiviral cytokines such as IFN g and TNF a upon antigen ...
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Apoptotic depletion of CD4+ T cells in idiopathic CD4+ T lymphocytopenia
... accelerated T cell death in at least some of our patients may relate to the enhanced sus- ceptibility of Fas-expressing T lymphocytes to cross-linking by Fas ...primary T cells, un- like ...
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Follicular regulatory T cells inhibit the development of granzyme B–expressing follicular helper T cells
... TFR cells inhibit the development of aberrant cytotoxic gene–expressing TFH cells, particularly in the context of an inflammatory ...TFR cells were influencing the ability of TFH cells to help ...
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Functional studies on human γδ T cells and their interactions with dendritic cells and B cells
... Vγ9Vδ2 T cells are the predominant subset in ...eukaryotic cells and many ...Vγ9Vδ2 T cells and which is not produced by human ...Vγ9Vδ2 T cells. HMB-PP can be converted ...
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Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients
... arthritogenic T-cell activity in RA patients, we have found that IL-7, in the context of synovial accessory cells, strongly stimulates T-cell IFN-γ and tumor necrosis factor alpha production without ...
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Immunoregulatory T cells in man Histamine induced suppressor T cells are derived from a Leu 2+ (T8+) subpopulation distinct from that which gives rise to cytotoxic T cells
... activate T suppressor cells that bear the Leu 2 (OKT8) ...cytotoxic T cells from antigen-specific suppressor T ...2+ cells isolated from peripheral blood were further separated ...
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Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
... impact T cell responses in patients with ...these cells are abundant in LP lesions and scarce in blood, we found no differences in the periph- eral blood samples collected from the HCs and patients with ...
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Specificity of T cells in synovial fluid: high frequencies of CD8+ T cells that are specific for certain viral epitopes
... EBV-specific T cells, are in cell cycle within synovial ...B cells as well as T cells are recruited into inflamed joints and, in EBV-seropositive individuals, a subpopulation of these B ...
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Decreased T helper 17 cells in tuberculosis is associated with increased percentages of programmed death ligand 1, T helper 2 and regulatory T cells
... + T lymphocytes through interactions between programmed cell death ligand-1 (PD-L1) from dendritic cells and PD-1 on T cells ...of T cell regulators, and the intracellular tail con- ...
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