T regulatory cells (Tregs)
Comprehensive Analysis of Frequency and Phenotype of T Regulatory Cells in HIV Infection: CD39 Expression of FoxP3+ T Regulatory Cells Correlates with Progressive Disease
... these cells and to see how they may differ from Tregs present in healthy controls and HIV-infected patients with chronic progressive ...⫹ T cells (42, 44, 45, 47, 56, ...⫹ T cells on a ...
11
Regulatory T cells in multiple sclerosis and myasthenia gravis
... by T lymphocytes with specificity to neuronal antigens in genetically susceptible ...in T regulatory cells ...CD4+ T cell subsets that mediate autoimmune ...by T effectors have ...
16
Activation of myeloid dendritic cells, effector cells and regulatory T cells in lichen planus
... dendritic cells; TLR: toll-like receptors; pDC: plasmacytoid dendritic cells; mDC: myeloid dendritic cells; IFN-α: interferon alpha; TNF-α: tumour necrosis factor alpha; Tregs: T ...
11
The role of regulatory T cells in cancer immunology
... immune cells. Abbreviations: Treg, T regulatory cells; TME, tumor microenvironment; iTreg, inducible Treg; Teff, T effector cells; IL, interleukin; ADO, adenosine; TGF-β, ...
13
Regulatory T cells induced by B cells: a novel subpopulation of regulatory T cells
... B cells have been shown to have a role in the fine equilibrium for immune ...B cells might contribute to immune modulation ...B cells in oral tolerance has been inves- tigated because ...
8
Upregulation of CD47 in Regulatory T Cells in Atopic Dermatitis
... Treg cells from AD mice. (A) FACS analysis of expression of CD47 in Treg cells from thymuses and spleens from normal and AD ...Treg cells isolated from normal spleens than in those isolated from ...
11
Unravelling the Functions of Regulatory T Cells during Infection
... However, not all studies have revealed that Treg function to control effector activation. Paradoxically, it has been shown that Treg provide protective re- sponses in some pathogen infections permitting timely entry of ...
14
Memory regulatory T cells reside in human skin
... Regulatory T cells (Tregs), which are characterized by expression of the transcription factor Foxp3, are a dynamic and heterogeneous population of cells that control immune responses and ...
11
Signatures of immune reprogramming in anti-CD52 therapy of MS: markers for risk stratification and treatment response
... endpoint will be used (Wilcoxon signed-rank test, Stu- dent’s t-test for paired samples, Sign-Test). In order to compare more than two successive measurements, the preferred methods of statistical analysis are ...
9
<p>Cancer Immunotherapies Targeting Tumor-Associated Regulatory T Cells</p>
... presentation cells (APCs), to induce APCs ’ ...conventional T cells (Tconv), and it is hardly secreted by Tregs because FoxP3 binds to and attenuates two transcrip- tion factors that are required for ...
12
Regulatory T cells: friend or foe in immunity to infection
... Tr cells in immune homeostasis is far from complete and there are a number of important unanswered ...do regulatory mechanisms control the development of autoimmunity, while at the same time permitting the ...
12
Impaired survival of regulatory T cells in pulmonary sarcoidosis
... Th cells contribute to this phenomenon, a previous study showed that sarcoidosis Th cells were responsive towards the suppressive capacity of healthy Tregs ...
11
Nature of Regulatory T Cells in the Context of Allergic Disease
... induce T-cell division but suppressed the generation of effector T cells induced by ...first cells to encounter antigen; DCs derived from the oral mucosa were not able to transfer tolerance, ...
5
Harnessing FOXP3+ regulatory T cells for transplantation tolerance
... effector T cells require different metabolic programs to ...effector T cells express high levels of the cell surface glucose transporter GLUT1 and engage the relatively energy- inefficient ...
8
Increased production of soluble CTLA 4 in patients with spondylarthropathies correlates with disease activity
... on T cells and its ligands, CD80 and CD86, present on the antigen presenting cells (APC) are the proto- typical costimulatory molecules ...Cytotoxic T lymphocyte associated molecule-4 (CTLA-4 ...
11
Homeostasis and Function of Regulatory T Cells in HIV/SIV Infection
... In contrast to the studies reviewed above, Tregs have been associ- ated with a favorable outcome of HIV infection (Fig. 2). The ob- servation that Treg frequency is higher in mucosal tissues than in the peripheral blood ...
8
Regulatory T Cells Resist Virus Infection-Induced Apoptosis
... CD4 T cells are driven to apoptosis by virus infection- and poly(I·C)-induced type I IFN (9, 11, 13, ...Treg cells. Treg cells are major regulators of self-reactive T cells and ...
9
Review Article Regulatory T cells and B cells: implication on autoimmune diseases
... latory T (Treg) cells play an essential role in the maintenance of homeostasis and prevention of autoimmune responses ...these cells are CD4+ cells that express CD25, an IL-2 receptor alpha ...
7
Natural regulatory T cells in malaria: host or parasite allies?
... blood cells (pRBCs) in vascular beds and a strong host pro- inflammatory response mediated by cytokines such as TNF-a [24], LT-a [25], and IFN-c [26], and effector cells such as CD4 [27,28] and CD8 T ...
9
Statins Induce the Accumulation of Regulatory T Cells in Atherosclerotic Plaque
... TCAAC T-3 ′ ; IL-17, sense 5 ′ -TCCCT CTGTG ATCTG GGAAG-3 ′ , antisense 5 ′ -CTCGA CCCTG AAAGT GAAGG-3 ′ ; IFN- γ , sense 5 ′ - CATTG AAAGC CTAGA AAGTC TG-3 ′ , antisense 5 ′ -CTCAT GAATG CATCC TTTTT CG-3 ′ ; and ...
8