TCA cycle intermediates
Sugar and organic acid utilisation in Pachysolen tannophilus and Pichia stipitis : a thesis presented in partial fulfilment of the requirements for the degree in Master of Science in Genetics at Massey University
... Wild-type strains of the K+ yeasts Pachysolen tannophilus and Pichia stipitis were assessed for their ability to utilise tricarboxylic acid TCA cycle intermediates and to fennent glucose[r] ...
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Systemic and central nervous system metabolic alterations in Alzheimer’s disease
... This metabolomics study performed using paired plasma and CSF samples from two well-defined groups highlights dysregulated systemic energy metabolism in AD and CNS-specific tryptophan pathway and creatinine alter- ...
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Faix, Benjamin (2017): Adaptation of plants to low-oxygen stress. Dissertation, LMU München: Fakultät für Biologie
... acids, TCA cycle intermediates such as citrate, fumarate and malate were also found to be significantly decreased in idhv plants in comparison with the wild ...
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Anaerobic Respiration Using a Complete Oxidative TCA Cycle Drives Multicellular Swarming in Proteus mirabilis
... of TCA cycle intermediates alters swarming differ- entiation of ...dative TCA cycle (aceE, sdhB, sdhC, and fumC mutant bacteria) resulted in aberrant swarming phenotypes (class II), we ...
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Evidence that 2-hydroxyglutarate is not readily metabolized in colorectal carcinoma cells
... of TCA cycle intermediates when the cells were treated with 2HG for 24 ...of TCA cycle intermediates from U- 13 C glucose were not statistically different upon the addition of ...
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The Mitochondrial Pyruvate Carrier and Metabolic Regulation
... Rutter’s laboratory was examining groups of mitochondrial proteins that are evolutionarily conserved, and noted the homologous YGL080W, YHR162W, and YGR243W genes which encode yeast Mpc1, Mpc2 and Mpc3, respectively ...
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Metabolomic profiling of the effects of melittin on cisplatin resistant and cisplatin sensitive ovarian cancer cells using mass spectrometry and biolog microarray technology
... repair and thus resistance to the lytic action of melittin in comparison with the cisplatin resistant A2780CR cells. After exposure to melittin, the levels of most of the significantly altered metabolites, particularly ...
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Metabolic control of gene transcription in non-alcoholic fatty liver disease: the role of the epigenome
... the TCA cycle and epi- genetic ...between TCA cycle dysfunction and epigenetic regulation of gene expression in the pathogenesis of the disease [50, ...
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Synergizing metabolic flux analysis and nucleotide sugar metabolism to understand the control of glycosylation of recombinant protein in CHO cells
... This indicates that the aim to replicate data by the sequential cultivation method was unsuccessful, however, these results suggest a case of steady state multiplicity - a difference in cell metabolism despite the use of ...
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1H NMR Based Serum Metabolic Profiling Reveals Differentiating Biomarkers in Patients with Diabetes and Diabetes Comorbidity
... patient's situation and the treatment strategy as a consequence affecting the success of the treatment. These co-morbidities are often challenging for physicians to manage because they can be present for years before ...
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Expanding primary metabolism helps generate the metabolic robustness to facilitate antibiotic biosynthesis in Streptomyces
... (glycolysis, TCA cycle, and amino acid me- tabolism) represented gene expansion events, such that they are overrepresented in this genus compared to the rest of the ...
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Adaptative biochemical pathways and regulatory networks in Klebsiella oxytoca BAS-10 producing a biotechnologically relevant exopolysaccharide during Fe(III)-citrate fermentation
... Results: Further phylogenetic analysis, based on 16S rDNA sequence, definitively confirmed that BAS-10 belongs to K. oxytoca species. In order to rationalize the biochemical peculiarities of this unusual enterobacteriun, ...
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Proteomic analysis of the effects of exogenous calcium on hypoxic-responsive proteins in cucumber roots
... the TCA cycle and in the synthesis of acetylcholine ...the TCA cycle to carry out cellular respiration; thus, pyruvate dehydrogenase links the glycolytic pathway to the TCA cycle ...
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Glucose and Lactate Consumption by the R3230 Mammary Adenocarcinoma.
... FAs mostly come from the diet. To be soluble in blood they bind to albumin. The albumin bound FAs are then removed from the blood for energy production. To be used, 2-carbon fragments are removed from the carboxyl end of ...
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Effect of triiodothyronine on mitochondrial energy coupling in human skeletal muscle
... the cycle, C2 and C3 of glutamate become ...of TCA cycle ...the TCA cycle flux calculated from our mathematical model is independent of both the amount of acetate ...
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Reprogramming of energy metabolism as a driver of aging
... In summary, reciprocal changes in PEPCK-C and PK with age are a determinant of aging. The mechanisms include disrupted energy homeostasis, as well as altered AMPK, TOR signaling, and autophagy. Consistently, ...
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Cis-Natural Antisense Transcripts Are Mainly Co-expressed with Their Sense Transcripts and Primarily Related to Energy Metabolic Pathways during Muscle Development
... Cis-natural antisense transcripts (cis-NATs) are a new class of RNAs identified in various species. However, the biological functions of cis-NATs are largely unknown. In this study, we investigated the transcriptional ...
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Influence of Arsenate and Phosphate on the Regulation of Growth and TCA Cycle in the Rice (Oryza sativa L ) Cultivars IR64 and Nayanmani
... The TCA cycle is a series of chemical reactions used by aerobic organisms to generate energy. Till date, very few reports exist on effect of arsenic on respira- tion in plants, although it has been reported ...
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Comparative Efficacy of Diethylcarbamazine, Nitazoxanide and Nanocomposite of Nitazoxanide and Silver Nanoparticles on the Dehydrogenases of TCA Cycle in Setaria cervi, in Vitro
... Since TCA cycle enzymes have certain biological functions that make them essential for the survival of parasite and therefore, efficacy of diethylcarbamazine (DEC), nita- zoxanide (NTZ) and a nanocomposite ...
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Engineering and systems-level analysis of Pseudomonas chlororaphis for production of phenazine-1-carboxamide using glycerol as the cost-effective carbon source
... the TCA cycle (AcCoA and CIT + ICIT) were present in significantly lower concentrations in HT66LSP than in ...reductive TCA cycle and a high activity of the glyoxylate shunt were observed in ...
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