TGF, transforming growth factor
Activation of the JNK-c-Jun pathway in response to irradiation facilitates Fas ligand secretion in hepatoma cells and increases hepatocyte injury
... transcription factor; BSA, bovine serum albumin; CM, conditioned medium; ELISA, enzyme-linked immunosorbent assay; ERK, extracellular signal-related kinase; FACS, fluorescence-activated cell sorting; FITC, ...
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Over-Production of Therapeutic Growth Factors for
... growth factor; protein production platform; protein packaging cell line; transforming growth factor 31.. β (TGF-β); GP2-293 cells 32.[r] ...
12
Original Article Effect of transforming growth factor-β1 on the expression of peroxisome proliferator-activated receptor β and scar formation in rabbit ears
... the TGF-β1 treated group, on day ...to TGF-β1 treatment, compared to control ...after TGF-β1 conduction, the dermis layer of the scars in TGF-β1 treated group was significan- tly thickened, ...
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Post translational processing of proteins implicated in the pathogenesis of Alzheimer's disease
... The APP-751 isoform was shown to be up-regulated and the APP-695 isoform down-regulated in response to neuronal injury in rat brain (Iverfeldt et a l , 1993). It is possible that this effect was mediated via the products ...
262
Transforming Growth Factor – β and Glioma
... that TGF-β has in the promotion of cancer cell is the inhibition of immune ...surveillance. TGF-β has the ability to suppress cytotoxic T-cells, dendritic cells and natural killer cells while simultaneously ...
5
Growth differentiation factor 9 and bone morphogenetic protein 15 expression in previtellogenic oocytes and during early embryonic development of Yellow-tail Kingfish Seriola lalandi
... the transforming growth factor β super family (TGF-β), GDF9 and BMP15 ...These growth factors stimulate the proliferation of granu- lose cells, but also suppress follicle stimulating ...
7
In Vitro Effects of Curcumin on Transforming Growth Factor-β-mediated Non-Smad Signaling Pathway, Oxidative Stress, and Pro‐inflammatory Cytokines Production with Human Vascular Smooth Muscle Cells
... recombinant TGF-β, anti- phospho-Smad2L (Ser245/250/255) and anti-rabbit Immunoglobulin-G (IgG)-horseradish peroxidase (HRP) antibody were obtained from Cell Signaling Technology (Beverly, MA, ...
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Differential expression of transforming growth factors alpha and beta in rat intestinal epithelial cells
... of transforming growth factor alpha (TGF alpha), and transforming growth factor beta (TGF beta) was assessed in isolated primary rat intestinal epithelial cells as ...
7
Loeys-Dietz syndrome type I and type II: clinical findings and novel mutations in two Italian patients
... Background: Loeys-Dietz syndrome (LDS) is a rare autosomal dominant disorder showing the involvement of cutaneous, cardiovascular, craniofacial, and skeletal systems. In particular, LDS patients show arterial tortuosity ...
5
Moniliformediquinone as a potential therapeutic agent, inactivation of hepatic stellate cell and inhibition of liver fibrosis in vivo
... Transforming growth factor-β1 (TGF-β1) is a major fibrotic growth factor in liver fibrosis ...by TGF-β in a fibroblastic cell type and plays a key role in the ...
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Safety study: is there a pathologic IGF-1, PDGF and TGF-ß cytokine expression caused by adjunct BMP-7 in tibial and femoral non-union therapy?
... like growth factor 1 (IGF-1), platelet-derived growth factor AB (PDGF-AB) and transforming growth factor beta (TGF-β) were compared between patients with the gold ...
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Regulation of transforming growth factor expression in rat intestinal epithelial cell lines
... and TGF beta 1, were observed in another intestinal epithelial cell line, designated ...of TGF beta 1 expression when compared to IEC-6 and IEC-17 cells maintained on ...
7
Effects of platelet derived growth factor and other polypeptide mitogens on DNA synthesis and growth of cultured rat liver fat storing cells
... platelet-derived growth factor (PDGF), epidermal growth factor (EGF), transforming growth factor (TGF)-alpha and TGF-beta, and basic fibroblast growth ...
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Interactions between stromal cell derived keratinocyte growth factor and epithelial transforming growth factor in immune mediated crypt cell hyperplasia
... the growth factor (0–20 ng/ml) to the explant culture system had no effect on epithelial cell proliferation; however, at higher doses (500 ng/ml) either KGF or TGF- a caused a twofold increase in ...
9
Original Article Effects of insulin-like growth factor 2 and its receptor expressions on corneal repair
... epidermal growth factor (EGF), fibroblast growth factor-β (FGF-β), heparin-like growth factor (HGF), keratinocyte growth factor (KGF), transforming ...
7
Safety and pharmacokinetics of recombinant human hepatocyte growth factor (rh HGF) in patients with fulminant hepatitis: a phase I/II clinical trial, following preclinical studies to ensure safety
... of growth and growth-inhibitory factors were elevated [27-29], and reciprocal action of these factors in FH patients results in impaired liver ...of transforming growth factor ...
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An Essential Role for Macrophage Migration Inhibitory Factor (MIF) in Angiogenesis and the Growth of a Murine Lymphoma
... (IL-1), IL-2, hematopoietic colony-stimulating factors (CSFs), platelet-derived growth factor (PDGF), and transforming growth factor (31 (TGF-j31) each can act as an autocrine growth fac[r] ...
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Genetic analysis of female infertility with the effect of human bmp15 and gdf9 genes: a review
... the transforming growth factor-β (TGF- β) super family: growth differentiation factor 9 (GDF9) and bone morphogenetic protein 15 (BMP15) originates from oocytes are played a very ...
6
and vascular endothelial growth factor in filtering bleb after trabeculectomy
... of Transforming growth factor beta-2 (TGF-β 2 ) and Vascular endothelial growth factor (VEGF) in filtering bleb tissues after trabeculectomy on rabbit eyes, and to discuss their ...
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Cooperative transforming activities of ras, myc, and src viral oncogenes in nonestablished rat adrenocortical cells.
... Cell lines infected with Harvey murine sarcoma virus or KiMSV produce transforming growth factors particularly transforming growth factor oa [TGF-ox] and TGF-13 4 that induce a transform[r] ...
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