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The Major Histocompatibility Complex (MHC)

MHC (MAJOR HISTOCOMPATIBILITY COMPLEX)

MHC (MAJOR HISTOCOMPATIBILITY COMPLEX)

... (MAJOR HISTOCOMPATIBILITY COMPLEX) MHC complex is group of genes on a single chromosome that codes the MHC ...antigens. Major as well as minor histocompatibility antigens (also ...

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Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes

Disruption and pseudoautosomal localization of the major histocompatibility complex in monotremes

... The major histocompatibility complex in monotremes

The characterization and chromosomal mapping of major histocompatibility complex (MHC)-containing BAC clones from platypus ...

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Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse

Major Histocompatibility Complex Variation in the Endangered Przewalski’s Horse

... The major histocompatibility complex (MHC) is a fundamental part of the vertebrate immune system, and the high variability in many MHC genes is thought to play an essential role in recognition of ...

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The Major Histocompatibility Complex Class I Genes of Zebrafish.

The Major Histocompatibility Complex Class I Genes of Zebrafish.

... (2007) A third broad lineage of major histocompatibility complex (MHC) class I in teleost fish; MHC class II linkage and processed genes. (2015) A comprehensive analysis of teleost MHC[r] ...

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Development and Use of Multimeric Major Histocompatibility Complex Molecules

Development and Use of Multimeric Major Histocompatibility Complex Molecules

... Department of Gastroenterology and Hepatology, Medizinische Hochschule Hannover, 30655 Hannover, Germany, 1 and Department of Pathology, Johns Hopkins University, Baltimore, Maryland 21205 2 Enumeration and analysis of ...

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The major histocompatibility complex class I immunopeptidome of extracellular vesicles

The major histocompatibility complex class I immunopeptidome of extracellular vesicles

... Within the immune system EVs have been reported to have mostly immunoinhibitory functions (6), although dendritic cell- and tumour cell-derived EVs have shown some promise in the stimulation of anti-tumour responses (7). ...

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Major Histocompatibility Complex Differentiation in Sacramento River Chinook Salmon

Major Histocompatibility Complex Differentiation in Sacramento River Chinook Salmon

... Bartley, D. M., and G. A. E. Gall, 1990 Genetic structure and netics 38: 437–441. gene flow in chinook salmon populations of California. Trans. Hughes, A. L., 1991 MHC polymorphism and the design of captive Am. Fish. ...

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Major Histocompatibility Complex Heterozygosity Reduces Fitness in Experimentally Infected Mice

Major Histocompatibility Complex Heterozygosity Reduces Fitness in Experimentally Infected Mice

... at major histocompatibility complex (MHC) loci confers enhanced resistance to infectious diseases (heterozygote advantage, HA, hypothesis), and overdominant selection should contribute to the ...

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Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant

Molecular analysis of major histocompatibility complex alleles associated with the lupus anticoagulant

... Major histocompatibility complex (MHC) class II alleles (HLA-DR and DQ) were determined by restriction fragment length polymorphisms (RFLP) in 20 patients with APA (lupus.. anticoagulant[r] ...

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Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex

Alloreactivity and Association of Human Natural Killer Cells with the Major Histocompatibility Complex

... Unit of Emerging and Re-Emerging Diseases, 1 Retrovirology, 2 and Parasitology, 3 International Center for Medical Research (CIRMF), Franceville, Gabon Received 28 July 1998/Returned for modification 5 October ...

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Regulation of major histocompatibility complex class II gene expression in trophoblast cells

Regulation of major histocompatibility complex class II gene expression in trophoblast cells

... * Corresponding author Abstract Trophoblast cells are unique because they are one of the few mammalian cell types that do not express major histocompatibility complex (MHC) class II antigens, either ...

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Correlation in chicken between the marker LEI0258 alleles and Major Histocompatibility Complex sequences

Correlation in chicken between the marker LEI0258 alleles and Major Histocompatibility Complex sequences

... Background: The LEI0258 marker is located within the B region of the chicken Major Histocompatibility Complex (MHC), and is surprisingly well associated with serology. Therefore, the correlation ...

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The Implications of Intergenic Polymorphism for Major Histocompatibility Complex Evolution

The Implications of Intergenic Polymorphism for Major Histocompatibility Complex Evolution

... Begun, D. J., and C. F. Aquadro, 1992 Levels of naturally occurring Klein, J., Y. Satta, C. O’hUigin and N. Takahata, 1993 The molec- DNA polymorphism correlate with recombination rates in D. ular descent of the ...

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Histocompatibility alloantigens in psoriasis and psoriatic arthritis  Evidence for the influence of multiple genes in the major histocompatibility complex

Histocompatibility alloantigens in psoriasis and psoriatic arthritis Evidence for the influence of multiple genes in the major histocompatibility complex

... C Murray, … , J L Decker, T P Nigra J Clin Invest. 1980;66(4):670-675. https://doi.org/10.1172/JCI109903. The frequency of HLA-A, B, and Cw antigens as well as the antigens expressed preferentially on B cells and ...

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Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy

Extended major histocompatibility complex haplotypes in patients with gluten sensitive enteropathy

... J Clin Invest. 1987;79(1):251-256. https://doi.org/10.1172/JCI112791. We have studied major histocompatibility complex markers in randomly ascertained Caucasian patients with gluten-sensitive ...

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Extended major histocompatibility complex haplotypes in type I diabetes mellitus

Extended major histocompatibility complex haplotypes in type I diabetes mellitus

... We have studied major histocompatibility complex markers in Caucasian patients with type I diabetes mellitus and their families. The frequencies of extended haplotypes that were composed of specific ...

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Sequences, Annotation and Single Nucleotide Polymorphism of the Major Histocompatibility Complex in the Domestic Cat

Sequences, Annotation and Single Nucleotide Polymorphism of the Major Histocompatibility Complex in the Domestic Cat

... This Article is brought to you for free and open access by the Department of Biological Sciences at NSUWorks. It has been accepted for inclusion in Biology Faculty Articles by an authorized administrator of NSUWorks. For ...

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The role of major histocompatibility complex molecules in luteal function

The role of major histocompatibility complex molecules in luteal function

... protease complex composed of multiple subunits that is responsible for the majority of intracellular protein turnover, and also generates peptides that are presented to T cells via class I MHC molecules (Figure 1; ...

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Conditional analysis of the major histocompatibility complex in rheumatoid arthritis

Conditional analysis of the major histocompatibility complex in rheumatoid arthritis

... significant association was p = 5.3 × 10 -6 for PTPN22. Clearly, the MHC is the most influential genetic region in RA susceptibility, but extensive LD makes isolating the precise loci difficult. We have used conditional ...

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Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

Major Histocompatibility Complex (MHC) Genes and Disease Resistance in Fish

... and the allelic variation is reminiscent of that found in trout, with as major difference that most (though not all) of the reported Atlantic salmon sequences have 2 domain sequences of the same lineage ...

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