The Non-genomic Pathway
ROLE OF GENOMIC AND NON-GENOMIC STEROIDS
... transduction pathway activated by the steroid ...a pathway quite distinct from the classic genomic and indeed most of its effect occur within seconds following addition of agonists and can be induced ...
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Pathway and Network Analysis of Transcriptomic and Genomic Data
... For example, when three replicates were used, even for a moderate inter-gene correlation 0.1, the false positive rates for the original statistics were approximately 50% or higher while only a few false positive sets ...
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Genomic analysis of metabolic pathway gene expression in mice
... regulate pathway genes were identified by analyzing for over-representation of identified pathway- associated gene eQTLs among eQTLs of the set of most differ- entially expressed genes in a given ...
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Comparative genomic analysis of C4 photosynthetic pathway evolution in grasses
... We found that the sorghum and maize C4 PEPC genes are on a long branch of their gene tree, grouped together with their suspected rice ortholog, showing possible adaptive evolution based on both a high Ka/Ks ratio and ...
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Integrated Genomic Analysis of the Ubiquitin Pathway across Cancer Types.
... from Genomic Data ...Only non-silent somatic mutations were used to calculate mutation ...of non-silent mutations found in that ...of non-silent mutations in that ...PI3K pathway ...
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Genomic, Pathway Network, and Immunologic Features Distinguishing Squamous Carcinomas
... Additionally, we identified miRNAs that were differentially abundant in SCC (n = 1,381) versus non-SCC (n = 9,436) tumors ( Figures S7 A [bold] and S7B). Of these, we highlight the two with the largest positive ...
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Review Article Genomic and non-genomic effects of glucocorticoids: implications for breast cancer
... Glucocorticoids have been widely used as co-treatment of patients with breast cancer (BC) due to reduction of chemotherapy-induced side effects such as nausea, lack of appetite, and inflammation. However, GC may exert a ...
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Genomic heterogeneity and efficacy of PI3K pathway inhibitors in patients with gynaecological cancer
... a non-randomised comparison, this finding comprises an important and clinically meaningful metric in a cohort of patients with heavily pretreated gynaecological cancer ...
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Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids
... the non-genomic pathways via ERK1/2 activation, and that some compounds exhibit activity corresponding to the modulation of only a single ...both genomic and non-genomic pathways had ...
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Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids.
... the non-genomic pathways via ERK1/2 activation, and that some compounds exhibit activity corresponding to the modulation of only a single ...both genomic and non-genomic pathways had ...
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Genomic and non-genomic pathways are both crucial for peak induction of neurite outgrowth by retinoids
... the non-genomic pathways via ERK1/2 activation, and that some compounds exhibit activity corresponding to the modulation of only a single ...both genomic and non-genomic pathways had ...
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Pathway-based outlier method reveals heterogeneous genomic structure of autism in blood transcriptome
... novel, pathway-based outlier method to two publicly available autism gene expression data sets from peripheral blood (TGen and ...three non- identical subgroups of samples with perturbations in the neuron ...
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Genomic diversity in ochratoxigenic and non ochratoxigenic strains of Aspergillus carbonarius
... strains. Non-ochratoxigenic strains showed 17 common missense variants located in different genes, mainly genes related with transferase activity and metabolic processes of carbohydrates, lipids, aminoacids, ...
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Development of a metabolic pathway transfer and genomic integration system for the syngas-fermenting bacterium Clostridium ljungdahlii
... dahlii shuttle vector for this purpose (Fig. 3a). The shuttle vector includes a pMB1 origin of replica- tion and bla selectable marker for high-copy-number maintenance and selection in E. coli, and a repL origin of ...
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Pivotal role of the muscle-contraction pathway in cryptorchidism and evidence for genomic connections with cardiomyopathy pathways in RASopathies
... microRNA, non-coding RNA, epigenetic, reproduction, and assisted ...with genomic regions involved in chromosome mutations was performed using data retrieved from Ensembl via BioMart data mining ...
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Overview of the structure-based non-genomic effects of the nuclear receptor RXRα
... 51. Yoshimura K, Muto Y, Shimizu M, Matsushima-Nishiwaki R, Okuno M, Takano Y, et al. Phosphorylated retinoid X receptor alpha loses its heterodimeric activity with retinoic acid receptor beta. Cancer Sci. 2007;98:1868 – ...
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Genomic characterization of high-risk non-muscle invasive bladder cancer
... the pathway to progression, and perhaps share a similar genomic landscape with tumors of advanced stage, such as those described in the ...TCGA. Genomic profile analysis showed a similar frequency of ...
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Differentiation between genomic and non-genomic feedback controls yields an HPA axis model featuring Hypercortisolism as an irreversible bistable switch
... in-silico pathway knock out tests on the extended HPA model indicate that the positive feedback on the genomic level mediated by the CRH hor- mone is vital for the bistability associated to ...
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Genomic instability and non-ionizing radiation
... • CRY should respond to ELF magnetic fields, and magnetic field effects should depend on the presence of functional CRY in the exposed cells or organisms. – CRY gene and protein expres[r] ...
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Non-additive effects in genomic selection
... where pr ijk (A 1 A 1 ), pr ijk (A 1 A 2 ), and pr ijk (A 2 A 2 ) are the probabilities of the genotypes A 1 A 1 , A 1 A 2 , and A 2 A 2 for the combination of the ith and jth individual and the kth marker, ˆa k and ˆd k ...
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