The Use of Non-Lymphoid Hematopoietic Cells for
G-CSF directly acts on mouse lymphoid-biased but not myeloid-biased hematopoietic stem cells
... Introduction Hematopoietic stem cells (HSCs) are cells able to self-renew and differentiate into all blood lineages. 1 Granulocyte colony-stimulating factor (G-CSF) is widely used in clinical ...
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Myeloid or Lymphoid Promiscuity as a Critical Step in Hematopoietic Lineage Commitment
... stem cells (HSCs) to lineage-restricted progenitors that ...whether cells with lineage- produce all lineages of mature blood ...immortalized cells or enriched mon to other ...multipotent cells ...
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Hematopoietic Stem Cells
... stem cells. The original donor of the stem cells no longer would be able to have access to these because all identifiers would be ...quent use at a later ...stem cells in the future or exactly ...
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Use of CAR-Transduced Natural Killer Cells in CD19-Positive Lymphoid Tumors
... CAR-NK cells was manufactured for each ...CAR-NK cells from a single cord-blood ...CAR-NK cells and the patient, may pave the way for a truly off-the-shelf product that could increase treatment ...
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Diminished Potential for B-Lymphoid Differentiation after Murine Leukemia Virus Infection In Vivo and in EML Hematopoietic Progenitor Cells
... undifferentiated lymphoid progenitors in the bone marrow of gammaretrovirus-infected animals and thereby contribute to the establishment of a premalignant ...
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UMBILICAL CORD BLOOD STEM CELLS AS A SOURCE OF NON-HEMATOPOIETIC CELLS: ROLE IN REGENERATIVE MEDICINE
... stem cells transplantation (PBSCT) have been carried out and promising results have been seen with reduction in insulin requirements for the ...of cells as UCB for this potential treatment of type I ...stem ...
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Lymphoid like stromal cells in a model of tertiary lymphoid organ formation
... precursor cells (pre- adipocytes) that develop into adipose cells, also have the potential to give rise to lymphoid tissue organizer cells on LTβR engagement, which represents the key ...
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Hematopoietic Stem and Progenitor Cells
... + cells and clonogenic progenitors can be achieved by culturing CD34 + cells for several days or weeks in media supplemented with combinations of cytokines such as IL-3, IL-6, SCF, Flt3L, TPO, GM-CSF and ...
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Natural Killer Cells and Type 1 Innate Lymphoid Cells Are New Actors in Non-alcoholic Fatty Liver Disease
... FIGURE 2 | Type 1 ILC during obesity-induced liver inflammation. Obesity is associated with adipose tissue dysfunction, increased gut permeability and dysbiosis. These alterations are responsible for the release of ...
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Alloantigen expression on non hematopoietic cells reduces graft versus leukemia effects in mice
... T cells into apoptosis and dysfunction during GVHD, resulting in a loss of GVL ...T cells and the target tissue, respectively, suggesting that the T cell defects driven by host epithelial alloantigen ...
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Hematopoietic stem cells from peripheral blood the perspective of non mobilized peripheral blood
... when compared with pre-freeze counts, with the wash step responsible for nearly half of this cell loss. However, Beshlawy et al. [48], using umbilical cord blood derived hematopoietic stem cells, detected ...
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A novel, neural potential of non hematopoietic human umbilical cord blood stem cells
... of cells for possible therapeutic application or reliable model for in vitro tests of terminal, neuronal differentiation, we needed to provide the strong physiological evidence for its functional differ- ...
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Development, Differentiation, and Diversity of Innate Lymphoid Cells
... Finally, lymphoid cells use immune-recognition receptors for development and to interact with infected or damaged ...‘‘NK cells’’ might indicate that they are an ILC1 ...
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Regulation of Tissue Homeostasis by Innate Lymphoid Cells
... or use of next generation RNA-Seq technology will be an invaluable exploratory tool to uncover the unique factors regulating the development and functional potential of murine and human ...
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The journey of developing hematopoietic stem cells
... of hematopoietic progenitors in the yolk sac, it is still unclear whether the yolk sac also generates ...or lymphoid progeny (Cumano et ...sac hematopoietic cells into conditioned newborn ...
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Hematopoietic stem cells and retroviral infection
... What Defines a HSC? HSCs are pluripotent stem cells that can generate all hemato-lymphoid cells. A cell must meet four basic functional requirements to be defined as a HSC: 1) the capability for ...
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Polycomb RING1B complexes in hematopoietic cells
... close-to-primary hematopoietic cell or, on the contrary, it would be that PRC1 complexes might be more dissimilar between cell types than ...of hematopoietic origin, and that the washed fractions were ...
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Exploring the role of CD248/endosialin/TEM-1 on lymphoid stromal cells in secondary lymphoid organs
... dendritic cells Follicular dendritic cells are an important cell type in the development of the germinal centre response, but understanding of these cells has previously been ...to use flow ...
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The evaluation and optimal use of rituximab in lymphoid malignancies
... B-cell non-Hodgkin’s lymphoma ...B-cell lymphoid malignancies of rituximab are ...optimal use of this drug, including timing and doses, is ...
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Bioengineering of Artificial Antigen Presenting Cells and Lymphoid Organs
... Antigen-presenting cells (APCs) act as a link between the innate and adaptive immune ...T cells, which play a key role in the adaptive immune ...T cells can be primed and amplified ex vivo before ...
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