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The vascular smooth muscle cells (VSMCs)

Stretching Vascular Smooth Muscle Cells on Micropatterned Surfaces

Stretching Vascular Smooth Muscle Cells on Micropatterned Surfaces

... 2.11: Smooth muscle cell contraction, A. Relaxed muscle cell, ...Contracted muscle cell 31 2.2.4 Vascular Smooth Muscle Cell Phenotypes While the previous section ...

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The Influence of Caldesmon Suppression on Proliferation and Motilities of Vascular Smooth Muscle Cells

The Influence of Caldesmon Suppression on Proliferation and Motilities of Vascular Smooth Muscle Cells

... of vascular smooth muscle cells (VSMCs) from the media to intima constitutes a critical step in the development of proliferative vascular ...control cells; third, the specific ...

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Spatial Distribution of Cytoskeletal  Mechanical Properties in Vascular Smooth Muscle Cells

Spatial Distribution of Cytoskeletal Mechanical Properties in Vascular Smooth Muscle Cells

... This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Abstract The mechanical properties on a whole basis of cell are extensively studied ...

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NOX4 downregulation leads to senescence of human vascular smooth muscle cells

NOX4 downregulation leads to senescence of human vascular smooth muscle cells

... human vascular smooth muscle ...of cells with DPI, a known inhibitor of flavoenzymes, as well as silencing of NOX4 lead to decreased production of ROS and induction of permanent growth arrest ...

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Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic
Transformation Of Vascular Smooth Muscle Cells

Involvement Of Vascular Aldosterone Synthase In Phosphate-Induced Osteogenic Transformation Of Vascular Smooth Muscle Cells

... . Vascular calcification is an active process, promoted by vascular smooth muscle cells (VSMCs) 6 ...ameliorates vascular calcification 11 ...of vascular calcification 1 . ...

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Proteome Analysis of Cultivated Vascular Smooth Muscle Cells from a CADASIL Patient

Proteome Analysis of Cultivated Vascular Smooth Muscle Cells from a CADASIL Patient

... a vascular de- menting disease caused by mutations in the NOTCH3 gene, most which are missense mutations leading to an uneven number of cysteine residues in epidermal growth factor–like repeats in the ...

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Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells

Exosomes from hyperglycemia-stimulated vascular endothelial cells contain versican that regulate calcification/senescence in vascular smooth muscle cells

... Background: To determine whether and how exosomes from human umbilical vein endothelial cells (HUVEC‑Exos) regulates vascular smooth muscle cells (VSMCs) calcification/senescence in ...

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Original Article Transcription factor Mef2C regulates the migration of vascular smooth muscle cells

Original Article Transcription factor Mef2C regulates the migration of vascular smooth muscle cells

... Department of Cardiovascular Surgery, Peking University People’s Hospital, Beijing, China Received August 16, 2016; Accepted October 18, 2016; Epub December 1, 2016; Published December 15, 2016 Abstract: Accumulating ...

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-induced injury of human vascular smooth muscle cells (HVSMCs)

-induced injury of human vascular smooth muscle cells (HVSMCs)

... Received October 11, 2017; Accepted October 30, 2017; Epub December 1, 2017; Published December 15, 2017 Abstract: Thoracic aortic dissection is a catastrophic acute aortic disease with a high postoperative mortality. ...

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Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells

Induction of cyclin A gene expression by homocysteine in vascular smooth muscle cells

... Treatment of quiescent RASMCs with 1 mM homocysteine or 2% calf serum for 36 h increased cyclin A mRNA levels by 8- and 14-fold, respectively, whereas homocysteine plus serum increased cyclin A mRNA levels by 40-fold, ...

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Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells

Atrial natriuretic polypeptide inhibits hypertrophy of vascular smooth muscle cells

... RASM cells, ANP (10(-7), 10(-6) M) significantly suppressed the basal incorporations of 3H-uridine and leucine by 50 and 30%, ...on vascular smooth muscle ...

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Specific binding of endothelin on human vascular smooth muscle cells in culture

Specific binding of endothelin on human vascular smooth muscle cells in culture

... endothelial cells. The binding of endothelin was studied on cultured human vascular smooth muscle cells obtained from umbilical ...per smooth muscle ...endothelial ...

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Original Article Role of prohibitin overexpression in proliferation of vascular smooth muscle cells

Original Article Role of prohibitin overexpression in proliferation of vascular smooth muscle cells

... rat vascular smooth muscle ...PHB cells proliferation in experimental group was significantly lower than that of control group (P < ...PHB cells of the experimen- tal group was ...

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Role of CD44 in the reaction of vascular smooth muscle cells to arterial wall injury

Role of CD44 in the reaction of vascular smooth muscle cells to arterial wall injury

... the vascular smooth muscle cell’s response to arterial wall ...on vascular smooth muscle cells in vitro and in vivo and assessed the role of CD44 in DNA ...Cultured ...

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Pressure promotes DNA synthesis in rat cultured vascular smooth muscle cells

Pressure promotes DNA synthesis in rat cultured vascular smooth muscle cells

... High blood pressure is one of the major risk factors for atherosclerosis. In this study, we examined the effects of pressure on cell proliferation and DNA synthesis in cultured rat vascular smooth ...

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Calcifying nanoparticles promote mineralization in vascular smooth muscle cells: implications for atherosclerosis

Calcifying nanoparticles promote mineralization in vascular smooth muscle cells: implications for atherosclerosis

... the cells and not directed to lysosomes could have become nidi for mineral ...the smooth muscle cells to osteogenic bone-forming ...in vascular smooth muscle cells ...

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Urotensin II-induced signaling involved in proliferation of vascular smooth muscle cells

Urotensin II-induced signaling involved in proliferation of vascular smooth muscle cells

... influx can also modulate the activity of PKD. 14 Vasoac- tive agents, such as endothelin-1, that bind Gq-coupled receptors, have been demonstrated to mediating PKD phosphorylation in various cell types. 22 Here, we show ...

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miR-27a regulates vascular remodeling by targeting endothelial cells' apoptosis and interaction with vascular smooth muscle cells in aortic dissection

miR-27a regulates vascular remodeling by targeting endothelial cells' apoptosis and interaction with vascular smooth muscle cells in aortic dissection

... of vascular smooth muscle cells was promoted by EC after downregulation of miR-27a due to enhancement of growth/differentiation factor 8 (GDF8) and repression of matrix metalloproteinase-20 ...

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KIF1C control of podosome formation in vascular smooth muscle cells

KIF1C control of podosome formation in vascular smooth muscle cells

... enriched micro-domains and the subsequent podosome formation at these sites. PTPD1 depletion could impair the formation of these micro-domains and the subsequent assembly of podosomes at these sites. Podosome formation ...

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An Endocrine Genetic Signal Between Blood Cells and Vascular Smooth Muscle Cells Role of MicroRNA-223 in Smooth Muscle Function and Atherogenesis

An Endocrine Genetic Signal Between Blood Cells and Vascular Smooth Muscle Cells Role of MicroRNA-223 in Smooth Muscle Function and Atherogenesis

... blood cells, such as leukocytes and platelets that are originally from hematopoietic cells in bone marrow, can secrete he- matopoietic lineage, cell-specific miR-223 into circu- lating ...enter ...

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