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The viral genome

Human Cytomegalovirus UL34 Binds to Multiple Sites within the Viral Genome

Human Cytomegalovirus UL34 Binds to Multiple Sites within the Viral Genome

... Viral Genome Ziqi Liu, a† Bonita ...the viral immune evasion gene US3. Analysis of the viral genome identified 14 potential UL34 binding ...

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Analysis of Human Cytomegalovirus oriLyt Sequence Requirements in the Context of the Viral Genome

Analysis of Human Cytomegalovirus oriLyt Sequence Requirements in the Context of the Viral Genome

... HCMV genome in order to dissect the roles of cis-acting elements of ...the viral genome to deepen our understanding of the complex mechanism of HCMV DNA ...

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Conservation of a Packaging Signal and the Viral Genome RNA Packaging Mechanism in Alphavirus Evolution

Conservation of a Packaging Signal and the Viral Genome RNA Packaging Mechanism in Alphavirus Evolution

... SINV genome and test the effects of these mutations on virus ...SINV genome between nt 733 and 1212 and cloned it into SINV/GFP to replace the original sequence ...

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High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome

High-Resolution Functional Profiling of a Gammaherpesvirus RTA Locus in the Context of the Viral Genome

... 3.8-kb viral genome locus in the con- text of the viral ...mutant viral library can be recovered from the lung tissues to generate a profile, which sets the stage for our future in vivo ...The ...

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Mapping of herpesvirus saimiri proteins on the viral genome: proteins dependent and not dependent on viral DNA synthesis.

Mapping of herpesvirus saimiri proteins on the viral genome: proteins dependent and not dependent on viral DNA synthesis.

... Compared with the in vitro translation of total RNA and the in vivo labeling of proteins, the identification of virus- specific proteins is facilitated by hybrid selected translation bec[r] ...

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Simian virus 40 large tumor antigen on replicating viral chromatin: tight binding and localization on the viral genome.

Simian virus 40 large tumor antigen on replicating viral chromatin: tight binding and localization on the viral genome.

... The electrophoretic and fluorographic analysis showed that T antigen binds in vitro to the origin-containing DNA fragment of protein-free replicating DNA (Fig. 4, lane 3), suggesting tha[r] ...

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Persistence of the Viral Genome in Adenovirus Type 12-infected Hamster Cells

Persistence of the Viral Genome in Adenovirus Type 12-infected Hamster Cells

... In growing cells infected with 3H-labeled adenovirus type 12, reduction of labeled loci paralleled the regression of T antigen-synthe- sizing cells.. This clearly indicated, in addition [r] ...

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Cytopathogenicity of border disease virus is correlated with integration of cellular sequences into the viral genome.

Cytopathogenicity of border disease virus is correlated with integration of cellular sequences into the viral genome.

... All cellular insertions so far identified in pestivirus genomes have been found within the NS2-3 encoding region. With re- spect to the nature of the cellular recombination partner two unrelated cellular sequences have ...

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Determination of the poliovirus RNA polymerase error frequency at eight sites in the viral genome.

Determination of the poliovirus RNA polymerase error frequency at eight sites in the viral genome.

... The basic approach used to determine the polymerase error frequency was to measure the frequency at which specific G residues in poliovirion RNA changed to another nucleotide during vira[r] ...

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The Essential Human Cytomegalovirus Gene UL52 Is Required for Cleavage-Packaging of the Viral Genome

The Essential Human Cytomegalovirus Gene UL52 Is Required for Cleavage-Packaging of the Viral Genome

... head-to-tail-linked viral genomes that upon packaging into capsids are cut into unit-length ...of viral DNA was not impaired in noncomplementing cells infected with the ⌬UL52 virus, but viral ...

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Nonpermissive infection of L cells by an avian reovirus: restricted transcription of the viral genome.

Nonpermissive infection of L cells by an avian reovirus: restricted transcription of the viral genome.

... PAGE analysis of the hybrids formed between '4C-labeled dsRNA of avian reovirus and ssRNA synthesized in L cells co-infected with avian and type 3 reoviruses. The cells were labeled betw[r] ...

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Adenovirus-Associated Virus Multiplication IX. Extent of Transcription of the Viral Genome In Vivo

Adenovirus-Associated Virus Multiplication IX. Extent of Transcription of the Viral Genome In Vivo

... minus strand transcribed in vivo was 70% as measured by hydroxyapatite analysis of hybrids formed between fragmented AAV minus strands. and RNA from AAV(Ad)- or AAV(HSV)-in-[r] ...

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VirusTAP: Viral Genome-Targeted Assembly Pipeline

VirusTAP: Viral Genome-Targeted Assembly Pipeline

... the viral genome (virus genome-targeted assembly pipeline: VirusTAP) by performing the following informatics steps: (1) quality trimming and adaptor removal, (2) read subtraction of host- and ...

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Viral Genome Methylation as an Epigenetic Defense against Geminiviruses

Viral Genome Methylation as an Epigenetic Defense against Geminiviruses

... the viral genome is targeted by small-RNA-directed ...that viral DNA and associated histone H3 are methylated in infected plants and that cytosine methylation levels are significantly reduced in ...

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Three Infectious Viral Species Lying in Wait in the Banana Genome

Three Infectious Viral Species Lying in Wait in the Banana Genome

... functional viral sequence in the host genome without any selective ...endogenous viral genome duplications and inversions observed may indicate a plant strategy to disarm any viral ...

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Evaluation of viral genome assembly and diversity estimation in deep metagenomes

Evaluation of viral genome assembly and diversity estimation in deep metagenomes

... natural viral communities, viruses present unique properties. Viral genomes are usually smaller than those of Bacteria and it has become affordable to ob- tain high coverage of viral metagenomes ...

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Sendai Virus C Proteins Regulate Viral Genome and Antigenome Synthesis To Dictate the Negative Genome Polarity

Sendai Virus C Proteins Regulate Viral Genome and Antigenome Synthesis To Dictate the Negative Genome Polarity

... the genome po- larity is determined is a central issue in RNA virus ...the viral genome is defined solely by different strengths of the cis-acting replication promoters located at the 3= ends of the ...

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Features Distinguishing Epstein-Barr Virus Infections of Epithelial Cells and B Cells: Viral Genome Expression, Genome Maintenance, and Genome Amplification

Features Distinguishing Epstein-Barr Virus Infections of Epithelial Cells and B Cells: Viral Genome Expression, Genome Maintenance, and Genome Amplification

... the viral genome to >20 copies per cell, such amplification was not normally observed after infection of primary epithelial cells or undifferentiated epithelial ...EBV genome was subsequently lost ...

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L1 Interaction Domains of Papillomavirus L2 Necessary for Viral Genome Encapsidation

L1 Interaction Domains of Papillomavirus L2 Necessary for Viral Genome Encapsidation

... (B) BPHE-1 cells were coinfected with recombinant SFV expressing BPV1 L1 (lanes 1 to 4) and L2 (lane 2), L2⌬91-129 (lane 3), or L2⌬91- 246 (lane 4). (C) BPHE-1 cells were coinfected with recombinant SFV expressing BPV1 ...

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Targeting mitotic chromosomes : a conserved mechanism to ensure viral genome persistence

Targeting mitotic chromosomes : a conserved mechanism to ensure viral genome persistence

... facilitate genome tethering must also be clearly ...diverse viral types. It is clear that all the viral types discussed in this review encode a protein that functions to tether viral genomes ...

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