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Therapy and Therapeutics

Unraveling molecular determinants of manual therapy: an approach to integrative therapeutics for the treatment of fibromyalgia and CFS/ME

Unraveling molecular determinants of manual therapy: an approach to integrative therapeutics for the treatment of fibromyalgia and CFS/ME

... non-pharmacological therapeutics, have also been extensively ...Behavioral Therapy (CBT) seems to lead to small benefits over control interventions in reducing pain, negative mood and disability at the end ...

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Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?

Combined analgesics in (headache) pain therapy: shotgun approach or precise multi-target therapeutics?

... This diversification of the pain system also explains why a wide range of different molecular substances can be used in the treatment of different pain states. Specific drugs directed at individual molecular targets are ...

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Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics

Upconversion Nanoparticles for Photodynamic Therapy and Other Cancer Therapeutics

... Photodynamic therapy (PDT) is a non-invasive treatment modality for a variety of diseases in- cluding ...photodynamic therapy, NIR trig- gered drug and gene delivery, as well as several other UCNP-based ...

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Emerging Implications of Nanotechnology on Cancer Diagnostics and Therapeutics

Emerging Implications of Nanotechnology on Cancer Diagnostics and Therapeutics

... The magnetic properties of paramagnetic nanoparticles have been used in an effort to concentrate drug delivery to tumors. In 1 such report, investigators used magnetic fields in an effort to concentrate ...

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AMICUS THERAPEUTICS INC

AMICUS THERAPEUTICS INC

... chaperone therapy because, when co-administered with ERT, migalastat is designed to bind to and stabilize the exogenous enzyme in the circulation in any patient receiving ...

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Integrin Targeted Therapeutics

Integrin Targeted Therapeutics

... leading to decreased pliability, perturbations in ion balance and increased adhesion and viscosity in blood vessels. Sickle cell anemia is characterized by episodes of ischemia-repurfusion [51], increased levels of in- ...

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The future of osteoarthritis therapeutics: targeted
pharmacological therapy

The future of osteoarthritis therapeutics: targeted pharmacological therapy

... Substantial progress has been made over the last five de- cades in non-hormonal OP treatment [38]. Bisphosphonates (BPs) are a class of drugs used to treat OP and related bone disease by preventing loss of bone mass. ...

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Intrabodies as therapeutics for Huntington's disease

Intrabodies as therapeutics for Huntington's disease

... Huntington’s disease (HD) is a devastating, genetic, neurodegenerative disease for which there is currently no effective therapy. The polyglutamine (polyQ) expansion that causes HD is in the first exon (HDx1) of ...

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MICROBUBBLES: ROLE IN THERAPEUTICS

MICROBUBBLES: ROLE IN THERAPEUTICS

... Ultrasound-mediated microbubbles destruction has been proposed as an innovative method for noninvasive delivering of drugs and genes to different tissues. Microbubbles are used to carry a drug or gene until a specific ...

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Time sensitive therapeutics

Time sensitive therapeutics

... fluid therapy invariably to be superior to liberal administration at all phases of acute respiratory distress syndrome (ARDS) [11], steroids to be inappropriate for all stages and forms of lung injury [12], ...

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A REVIEW ON TOPICAL THERAPEUTICS IN PSORIASIS

A REVIEW ON TOPICAL THERAPEUTICS IN PSORIASIS

... Topical therapy remains a key component for the management of most of the patients with ...topical therapy alone and moderate to severe form is usually treated with phototherapy, conventional systemic ...

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Antimalarial pharmacology and therapeutics of atovaquone

Antimalarial pharmacology and therapeutics of atovaquone

... antimalarial therapy that were not explained by drug resistance mutations, and patients with body weight >100 kg have a marked increased chance of treatment failure compared to <100 kg patients, both of ...

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Pro-angiogenic therapeutics for preeclampsia

Pro-angiogenic therapeutics for preeclampsia

... mouse, creating the “borderline hypertensive” strain. BPH/5 mice have a slightly higher blood pressure at base- line compared to C57 mice, which are used as control. When these animals become pregnant, blood pressure re- ...

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Strategizing the Development of Alzheimer’s Therapeutics

Strategizing the Development of Alzheimer’s Therapeutics

... The use of GSK-3 β inhibitors as a means of treating AD is being evaluated. In mouse models, inhibition of GSK-3 β resulted in reduced tau phosphorylation, tauopathy, neurodegeneration, neurofibrillary tangle formation, ...

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The Applications of Aptamers in the Field Of Therapeutics

The Applications of Aptamers in the Field Of Therapeutics

... cancer therapy is done by targeting cell surface biomarkers by cancer-targeting drugs including therapeutic antibodies and small molecule inhibitors, target cell surface biomarker ...

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MAGNETIC DRUG DELIVERY IN THERAPEUTICS

MAGNETIC DRUG DELIVERY IN THERAPEUTICS

... History: Magnetically Modulated system for drug delivery is a young field. In 1957, the surgeon Gilchrist published a seminar paper on selective inductive heating of lymph nodes after injection of 20-100nm sized ...

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ALZHEIMER'S AND CURRENT THERAPEUTICS: A REVIEW

ALZHEIMER'S AND CURRENT THERAPEUTICS: A REVIEW

... In vitro technology has given new insight to explore the potency of plant cell tissue culture to produce valuable chemical compounds as that of parent plant [59]. The advancement in plant tissue culture method for ...

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International Journal of Pharmacy & Therapeutics

International Journal of Pharmacy & Therapeutics

... of therapy should be made taking into consideration aspects such as the location of the excess hair, its association with complex anomalies and age of the ...

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Dna origami and bionanotechnology: an efficacious tool for modern therapeutics and drug delivery

Dna origami and bionanotechnology: an efficacious tool for modern therapeutics and drug delivery

... provide therapy and imaging functionality itself, this is usually overcome by binding some type of nano payload such as antibody protein [19] , immunostimulatoryoligo DNA [60] , drug molecules [23, 61] or ...

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Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C

... targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific ...targeted therapeutics, the experience with MMC suggests that prediction of ...

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