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tissue inhibitor of metalloproteinases

Metalloproteinases and tissue inhibitor of metalloproteinases in mesothelial cells  Cellular differentiation influences expression

Metalloproteinases and tissue inhibitor of metalloproteinases in mesothelial cells Cellular differentiation influences expression

... J Clin Invest. 1993;91(4):1792-1799. https://doi.org/10.1172/JCI116390. Mesothelial cells play a critical role in the remodeling process that follows serosal injury. Although mesothelial cells are known to synthesize a ...

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dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases

dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases

... for tissue inhibitor of metalloproteinases (TIMPs) by first screening multiple gRNA target sites using a luciferase-based promoter-reporter system and next confirmed the effective TIMP induction in ...

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Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

... matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in human non-pigmented ciliary epithelial cells ...

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In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases 1

In vitro suppression of programmed cell death of B cells by tissue inhibitor of metalloproteinases 1

... of tissue inhibitor of metalloproteinases ...metalloproteinase inhibitor (BB-94), confers resistance to apoptosis induced by both CD95-dependent and -independent (cold shock, serum ...

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Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity

Engineered Tissue Inhibitor of Metalloproteinases-3 Variants Resistant to Endocytosis Have Prolonged Chondroprotective Activity

... 21201 Tissue inhibitor of metalloproteinases-3 (TIMP-3) is a central inhibitor of matrix-degrading and sheddase families of metallo- ...the inhibitor are regulated by the balance ...

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A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in sorsby's fundus dystrophy

A novel tissue inhibitor of metalloproteinases-3 mutation reveals a common molecular phenotype in sorsby's fundus dystrophy

... Newcastle upon Tyne, NE2 4AA, United Kingdom, and the ‡‡Department of Ophthalmology, Royal Victoria Infirmary, Newcastle upon Tyne, NE1 4LP, United Kingdom Sorsby’s fundus dystrophy (SFD) is a dominantly in- herited ...

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Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation

Localization of the Functional Domains of Human Tissue Inhibitor of Metalloproteinases-3 and the Effects of a Sorsby's Fundus Dystrophy Mutation

... of tissue inhibitor of metalloproteinases-3 (TIMP-3), specifically to assess the contribution of the amino- and carboxyl- terminal domains of the molecule to its matrix metallo- proteinase (MMP) ...

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Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases 3 (TIMP 3)

Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases 3 (TIMP 3)

... 2001. Tissue inhibitors of metalloproteinases regulate ECM degradation by matrix metalloproteinases ...for tissue inhibitor of metalloproteinases-3 (TIMP- 3), the only TIMP known ...

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Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma

Distinct localization of collagenase and tissue inhibitor of metalloproteinases expression in wound healing associated with ulcerative pyogenic granuloma

... of metalloproteinases in tissue remodeling associated with wound healing, we used in situ hybridization to localize the expression of collagenase and tissue inhibitor of ...

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Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3

Suramin inhibits osteoarthritic cartilage degradation by increasing extracellular levels of chondroprotective tissue inhibitor of metalloproteinases 3

... loproteinase inhibitor, tissue inhibitor of metalloproteinases (TIMP)-3, through blocking its interaction with the endocytic scavenger receptor, low-density lipoprotein receptor –related ...

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Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice

Tissue inhibitor of metalloproteinases-3 mediates the death of immature oligodendrocytes via TNF-α/TACE in focal cerebral ischemia in mice

... Cell surface sheddases, including TNF-a converting enzyme (TACE) and stromelysin-1 (MMP-3) regulate the TNF superfamily of death receptors by activating the ligands and removing the death receptors from the cell surface. ...

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Monocyte Procollagenase and Tissue Inhibitor of Metalloproteinases

Monocyte Procollagenase and Tissue Inhibitor of Metalloproteinases

... The work described in this report identifies differences between human monocytes and macrophages both in basal (spontaneous) levels of procollagenase and TIMP secretion [r] ...

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Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Inflammation and Fibrosis of Skeletal Muscles

Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Inflammation and Fibrosis of Skeletal Muscles

... Matrix MetalloProteinases (MMPs) and Tissue Inhibitors of MetalloPro- teinases (TIMPs) have been involved in myoblast migration, fusion and various physiological and pathological remodeling situations ...

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Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics

Engineering of tissue inhibitor of metalloproteinases mutants as potential therapeutics

... nontargeted metalloproteinases or the inhibitor concentration may not have reached an effective level in the target ...MMP inhibitor Marima- stat (British Biotech Pharmaceuticals, Oxford, UK) was ...

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Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens

Effect of prostaglandin analogs on matrix metalloproteinases and tissue inhibitor of metalloproteinases in eyelid muscle specimens

... While our findings suggest that PAP may be related to MMP/TIMP alterations in adipose and collagen tissue than in the muscle itself, the small sample size limits our find- ings and larger studies are needed to ...

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Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

Bimatoprost, latanoprost, and tafluprost induce differential expression of matrix metalloproteinases and tissue inhibitor of metalloproteinases

... Abbreviations BAB: blood-aqueous barrier; DMSO: dimethyl sulfoxide; FBS: fetal bovine serum; FiVerHy: fibrillin-1, versican, and hyaluronan; HNPCEC: human non- pigmented ciliary epithelial cell; IOP: intraocular ...

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Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms

Phylotranscriptomic analysis uncovers a wealth of tissue inhibitor of metalloproteinases variants in echinoderms

... 2.1. Tissue preparation, sequencing and assembly Forty-one echinoderm specimen samples (tube feet, pinnules or body-wall tissue from adults) were preserved in Qiagen RNAlater  (Qiagen, Valencia, CA, USA), ...

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Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor

Imbalances between matrix metalloproteinases (MMPs) and tissue inhibitor of metalloproteinases (TIMPs) in maternal serum during preterm labor

... A number of studies have shown that IUI[19–22], spontaneous rupture of the membranes [11,21–27] and parturition[21– 24,26,28] either term or preterm are associated with elevated MMP-9 co[r] ...

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Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts

Regulation of the expression of tissue inhibitor of metalloproteinases and collagenase by retinoids and glucocorticoids in human fibroblasts

... To examine any possible effects upon total new protein synthesis by all-trans-retinoic acid or dexamethasone, replicate cultures of human skin fibroblasts were initiated in 35-mm-diamete[r] ...

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Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases 1  Implications for regulation of matrix degradation in liver

Human hepatic lipocytes synthesize tissue inhibitor of metalloproteinases 1 Implications for regulation of matrix degradation in liver

... J Clin Invest. 1992;90(1):282-287. https://doi.org/10.1172/JCI115850. Hepatic lipocytes play a central role in the pathogenesis of liver fibrosis, both via production of extracellular matrix proteins and through ...

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