total floating time
Lalitha Kumari P, Vasanth PM*, Suresh K, Ramesh T, Ramesh Malothu
... bilayer floating tablets of Quinapril HCl by direct compression ...lag time of 17 sec, total floating time of 12 hrs and drug release of ...retention time and give better disease ...
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Design and Development of Hydrodynamically Balanced Tablet of Itopride
... with effervescing agent sodium bicarbonate and citric acid. It was found that the formulation with maximum swelling indices showed slower release of drug. All the formulations were prepared by direct compression method. ...
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Formulation Development and Evaluation of Sustain Release Gastroretentive Floating Tablets of Prochlorperazine Dimaleate
... retentive floating tablets of Prochlorperazine dimaleate (PCZ) were prepared by direct compression method using altered concentrations of HPMC K4, HPMC K15 and PVP K30 as ...lag time, total ...
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DEVELOPMENT AND EVALUATION OF BILAYER FLOATING DOSAGE FORM OF CARBIDOPA AND LEVODOPA FOR TREATMENT OF PARKINSON’S DISEASE
... HPLC. Floating Lag Time is the time interval taken by the tablets to start ...The time requires for the tablet to rise to the surface and float is determined as floating lag ...
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FORMULATION DEVELOPMENT AND EVALUATION OF GASTRORETENTIVE FLOATING TABLETS OF BETAHISTINE HYDROCHLORIDE
... In the present study 9 formulations with vari able concentration of polymer (HPMC-K15, HPMC-K4) were prepared by direct compre- ssion method and evaluated for physicochemical properties, buoyancy lag ti me, total ...
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A FORMULA OPTIMIZATION OF NIFEDIPINE TABLET COMBINATION WITH FLOATING MUCOADHESIEVE SYSTEM IN A SIMPLEX LATTICE DESIGN
... Granules were done by mixing Nifedipine solid dispersion and sodium citricum. Gelatin and Carbopol 934P are mixed, then this mixture adding by first mixture. Sodium bicarbonate and Avicel PH 102 was mixed by second ...
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Volume 3 | Issue 2 - 2013
... release floating tablets of Mirtazapine an Antidepressant which was used as model drug with a rapid and complete, absorption but, due to first-pass metabolism, absolute bioavailability is ...variation, ...
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An Approach of Developing Floating Tablet of Lisinopril
... residence time that entailed a development of an optimized gastro retentive floating tablets ...lag time, total floating time, swelling ability and in vitro release studies were ...
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Formulation and Evaluation of Floating Tablets of Sitagliptin with Extract of Triphala
... lag time (Y2), total floating time (Y3), in-vitro drug release (Y4), and T50% ...prepared floating tablets were subjected to all post compression parameters such as hardness, ...
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FORMULATION DEVELOPMENT AND EVALUATION OF FLOATING TABLETS CONTAINING NIZATIDINE
... All the batches of prepared tablets were evaluated for various physical parameters like weight variation, hardness, friability and drug content uniformity. The results are shown in Table 2. The hardness of all the ...
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Design and characterization of nizatidine effervescent floating matrix tablets employing semisynthetic rate-retarding polymers
... release floating tablets employing three grades of HPMC K4M, HPMC K15M and HPMC K100M in four ratios ...with floating lag time of 1.2 min and total floating time of >14 ...
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DEVELOPMENT AND EVALUATION OF GASTRORETENTIVE FLOATING TABLET OF ROSUVASTATIN
... of time, thus, minimizing or eliminating side effects and improving ...out floating lag time and total floating time, in-vitro drug release studies and release kinetics ...
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FORMULATION AND EVALUATION OF FLOATING MICROSPHERES OF DIACEREIN BY IONIC GELATION METHOD
... Formulation F9 showed good results with respect to the various evaluation parameters, so it was selected as the optimized formulation. From the Pre-formulation studies for drug excipient compatibility it was observed ...
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FORMULATION AND IN VITRO EVALUATION OF FLOATING TABLETS OF TELMISARTAN
... of time. While the system is floating on the gastric contents, the drug is released slowly at the desired rate from the ...telmisartan floating tablets were prepared by using different grades of ...
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Formulation development and evaluation of gastroretentive floating tablets of ambroxol hydrochloride
... gastroretentive floating drug delivery system of ambroxol hydrochloride, which acts as a mucolytic agent that is reported to be useful in gastric neoplasms which are designed to increase the gastric residence ...
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A Comprehensive Review on Development and Investigational Strategies for Biphasic Site-Specific Floating Cum Bioadhesive Drug Delivery System
... The floating lag time (FLT), density, and total floating time (TFT) are now considered as essential parameters for the majority of evaluations describing the floating capability ...
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DESIGN AND IN VITRO CHARACTERIZATION OF GASTRO-RETENTIVE BILAYER FLOATING TABLET OF METOPROLOL TARTRATE
... (blockade effect) having half life 3-4hrs, which necessitates the administration twice a day in 25/50 mg. The polymers used are HPMC K4M, K15M, Ethyl cellulose and Xanthan gum, Guar gum, as gel forming agents and sodium ...
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FORMULATION AND EVALUATION OF LOSARTAN FLOATING TABLETS EMPLOYING A NEW MODIFIED STARCH – OPTIMIZATION BY 23 FACTORIAL DESIGN Swathi G * , K. P. R. Chowdary and A.Muralidhar RaoDOWNLOAD/VIEW
... as floating enhancers. Losartan floating tablets were formulated as per 2 3 factorial ...losartan floating tablet formulations were prepared employing selected combinations of the levels of the three ...
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A COMPREHENSIVE REVIEW ON GASTRORETENTIVE FLOATING TABLET OF CAPTOPRIL USING NATURAL AND SYNTHETIC POLYMER WITH COMPARISION OF POLYMER EFFICACY
... Sathivaraj S Investigated is to prolong the gastric residence time of Lornoxicam by fabricating it into a floating sustained release matrix tablets. Lornoxicam, a potent oxicam group of non-steroidal ...
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Novel swellable polymer of orchidaceae family for gastroretentive drug delivery of famotidine
... The present research proposed a novel formulation using salep, a new hydrogel and swellable polymer, to develop a gastroretentive matrix tablet. Investigation of the prepara- tion, characterisation, and in vitro release ...
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