Tramadol Hydrochloride
Formulation Optimization of Sustained Release Resinate Microcapsules of Tramadol Hydrochloride by Using 32 Factorial Design
... The tramadol hydrochloride-resin complexes were prepared by a batch processes. For the batch method, the previously purified indion 254 resin particles (100 mg of dry weight resin) were dispersed in a 2 % ...
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Development and validation of first order derivative spectrophotometric method for simultaneous estimation of tramadol hydrochloride and diclofenac sodium in bulk and synthetic mixture
... of Tramadol hydrochloride (TRA) and Diclofenac Sodium (DIC) by employing first order derivative method by using methanol as ...of Tramadol hydrochloride and 273.75 nm (zero cross point of ...
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POLYMORPHIC CHARACTERIZATION OF TRAMADOL HYDROCHLORIDE USING DIFFERENTIAL SCANNING CALORIMETRY
... Tramadol was procured as a gift sample from Research Centre in Vadodadara. All the other chemicals were purchased from Sigma Aldrich and TCI Chemicals. DSC instrument was Make of Metler Toledo at KLE University ...
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FORMULATION AND IN VITRO EVALUATION OF SUSTAINED RELEASE TABLETS OF TRAMADOL HYDROCHLORIDE
... Sustained release provides the most desirable dosing regimens with effective pharmacokinetic profile and pharmacodynamic response. This is potentially useful to overcome problems associated with conventional dose and has ...
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FORMULATION AND EVALUATION OF SUSTAINED RELEASE MATRIX TABLETS OF TRAMADOL HYDROCHLORIDE AND STUDY IT’S RELEASE (DISSOLUTION) KINETICS
... for tramadol hydrochloride is (±)cis – 2 - [ ( dimethylamino ) methyl ] – 1 - ( 3methoxyphenyl ) cyclohexanol ...hydrochloride. Tramadol hydrochloride was first introduced into clinical ...
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In vitro thermodynamic and spectroscopic investigation on the interaction of tramadol hydrochloride with bovine serum albumin measured by fluorescence quenching method
... To interpret the pharmacokinetics and pharmacodynamics properties of a drug molecule, plasma protein binding plays a substantial factor. The present study has been done to investigate the interaction of Tramadol ...
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FORMULATION DEVELOPMENT AND EVALUATION OF MOUTH DISSOLVING TABLET OF TRAMADOL HYDROCHLORIDE
... and mixed using geometric dilution method to improve the drug distribution and content uniformity and then triturated well in a mortar. Wet granulation, was carried out with moisture activation. The final mass was passed ...
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Stability-Indicating HPLC Method for the Simultaneous Determination of Paracetamol and Tramadol Hydrochloride in Fixed-Dose Combination Tablets
... and tramadol hydrochloride in fixed-dose combination tablets have been developed and validated per the International Conference on Harmonization ...and tramadol hydrochloride under stress ...
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A prospective study on injection tramadol hydrochloride as a labour analgesic and its effect on duration of labour
... The American Academy of Paediatrics and American college of Obstetricians and Gynaecology (2007) have specified that it is the responsibility of the obstetrician or certified midwife in consultation with an ...
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A comparison of epidural Butorphanol Tartrate and Tramadol hydrochloride for Postoperative analgesia using csea technique
... , Tramadol hydrochloride and fentanyl citrate, a new era in pain relief has ...as Tramadol hydrochloride is a synthetic 4-phenyl-piperdine analog of codeine with a dual mechanism of ...
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Taste Masking of Tramadol Hydrochloride by Polymer Carrier System and Formulation of Rapidly Disintegrating Tablets using Factorial Design.
... The objective of this study was to formulate and optimize taste masked rapidly disintegrating tablet of intensely bitter drug tramadol hydrochloride by 3 factorial design. The drug polymer complex was ...
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Formulation and evaluation of mouth dissolving tablet of tramadol hydrochloride
... of tramadol hydrochloride by sublimation method with a view to enhance patient ...compliance. Tramadol hydrochloride is a centrally acting analgesic, which is orally and intravenously ...
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Design and characterization of controlled release resinates of tramadol hydrochloride
... In vitro dissolution study was carried out in triplicate for resinates equivalent to 100 mg of tramadol hydrochloride placed into 900 ml of Dissolution medium, by using the USP paddle apparatus (Electrolab ...
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RP-HPLC method for estimation of tramadol hydrochloride and paracetamol in pharmaceutical formulation
... Paracetamol (PCM) is thought to act primarily in the CNS, increasing the pain threshshold by inhibiting both isoforms of cyclooxygenase, COX-1 and COX-2, enzymes involved in prostaglandin (PG) synthesis. Unlike NSAIDS, ...
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EFFECT OF EXCIPIENTS ON THE RELEASE OF TRAMADOL HYDROCHLORIDE FROM BIODEGRADABLE POLYMERIC IMPLANTS
... The Drug Loading Efficiency of Implants: The loading dose has a significant effect on resulting release kinetics along with drug solubility. In case of freely water-soluble drugs, the porosity of matrix upon drug ...
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Evaluation of clinical anesthetic effect after tramadol hydrochloride addition to xylazine-ketamine total injectable general anesthesia in cats undergoing scrotal castration
... Xylazine hydrochloride is an α2 adrenoreceptor agonist widely used in cats for its sedative, analgesic and muscle relaxant effects (Pypendop, ...Ketamine hydrochloride is a dissociative anesthetic with ...
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DESIGN OF TRAMADOL HYDROCHLORIDE LOADED SOLID LIPID NANOPARTICLES BASED GELS FOR PAIN MANAGEMENT
... Tramadol hydrochloride, a centrally acting oral analgesic, has high solubility and bioavailability in the biological fluids and thus possesses a major drawback of adverse effects (since it reaches a high ...
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Analytical Method Development And Validation Of Genotoxic Impurity, 2-Chloropropane, In Tramadol Hydrochloride Drug Substance Using Head Space Gas Chromatography
... Hcl, Tramadol HCl ...[16-18]. Tramadol hydrochloride is a codeine synthetic analogue with analgesic ...properties. Tramadol hydrochloride acts as agonist for receptors of delta-opioid, ...
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A UV SPECTROPHOTOMETRIC ASSAY OF SUSTAINED RELEASE BRANDS OF TRAMADOL HYDROCHLORIDE
... The two different brands (CONTIN – SR and TRAMAZAC – TC) were purchased from different medical store in trichy, Tamilnadu. The all tablets of CON were labelled to contain 100mg of Tramadol hydrochloride per ...
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Synthesis of related substances of Tramadol hydrochloride, analgesic drug
... Tramadol hydrochloride is a mild, non-addictive, centrally acting binary analgesic agent, during the process development of Tramadol hydrochloride, four related substances (Impurities) were ...
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