TRANSCRIPTIONAL ACTIVATION
Identification of two independent transcriptional activation domains in the Autographa californica multicapsid nuclear polyhedrosis virus IE1 protein.
... of activation by DE ...affect transcriptional activation. Transcriptional inhibition domains that are constituted from positively charged amino acids are known to exist in transcrip- tional ...
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Transcriptional Activation Domains of the Candida albicans Gcn4p and Gal4p Homologs
... be transcriptional repressors in ...cerevisiae transcriptional activators were found to have ...and transcriptional activation domain similarities is provided (see Table S1 in the supplemental ...
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Molecular mechanism of transcriptional activation by oestrogen receptor alpha
... Repeated attempts to isolate D rosophila p i 60 hom olog by expression screening or by amplification of cDNA with degenerate oligonucleotides were unsuccessful. Indeed, sequence homology searches were unable to identify ...
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Regulation of Hepatitis C Virus Replication by Nuclear Translocation of Nonstructural 5A Protein and Transcriptional Activation of Host Genes
... mutation in the NS5B RNA-dependent RNA polymerase. SGR-NS5A-vX are subgenomic replicons carrying NS5A variant sequence vX; SGR-Nim is the wt replicon (24); SGR-GND is the nonreplicative control replicon. NTR, ...
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Transcriptional activation by the mouse oestrogen receptor
... To assess if the amounts of functional wild-type and mutant receptor proteins in transfected cells were similar the expression plasmids were transfected into COS-1 cells and extracts from these cells tested for the ...
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dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases
... dCas-mediated transcriptional activation and whether there are interactions between the endogenous transcription factors and the synthetic transactivator is ...
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Transcriptional Activation in Yeast Cells Lacking Transcription Factor IIA
... because activation domains can interact with TFIIA, increase recruitment of TFIID and TFIIA to the promoter, and promote isomerization of the TFIID-TFIIA-TATA ...for activation by heat shock factor, Ace1, ...
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Transcriptional Activation of Human GD3 Synthase (hST8Sia I) Gene In curcumin-Induced Autophagy in A549 Human Lung Carcinoma Cells
... the activation of NF-κB in human colon cancer cells, demonstrating that curcumin suppressed NF- κB via AMPK activation ...AMPK activation in ovarian cancer cells ...triggered transcriptional ...
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In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila
... Cas9-mediated transcriptional activation have recently been developed, allowing target genes to be overexpressed from their endogenous genomic ...dCas9 activation in a multicellular animal. ...
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Transcriptional activation and dimerisation properties of oestrogen receptor β
... characterised transcriptional activation dom ains, activation function 1 (API) in the N -term in u s and activation function 2 (AF2) in the C -term ...
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Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone.
... MDV, where the vast majority of the stable LTR insertions are localized (15). This finding has now been corroborated by at least two other studies involving coinfection of HVT or MDV with avian leukosis virus (8a, 13). ...
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Transcriptional activation of USP16 gene expression by NFκB signaling
... codon, and translation frame. USP16 has been reported to contribute to the somatic stem-cell defects in DS and reduce the self-renewal of multiple somatic stem cells [17], suggesting that some of the pathological ...
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Genetic evidence for transcriptional activation by the yeast IME1 gene product.
... Subcellular distribution of an fusion protein: T h e idea that IMEl is a transcriptional acti- vator predicts that IMEl should be a nuclear protein. We used indirect immunofluorescence to examine the subcellular ...
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Molecular mechanism of transcriptional activation of angiotensinogen gene by proximal promoter
... acetyltransferase (CAT) assays with 5'-deleted constructs showed that the proximal promoter region from -96 to +22 of the transcriptional start site was enough to express HepG2-specific CAT activity. ...
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Mechanisms of Inhibition of Nuclear Hormone Receptor-Dependent Hepatitis B Virus Replication by Hepatocyte Nuclear Factor 3β
... the transcriptional activation domains of this polypeptide (32, ...amino-terminal transcriptional activation domain of HNF3 (32, 33) was shown to be primarily respon- sible for inhibiting ...
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Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
... E2 transcriptional repression function is also independent of ...the transcriptional silencing function of HPV11 E2 ...E2 transcriptional repression function ...iologic transcriptional ...
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How the Rgt1 Transcription Factor of Saccharomyces cerevisiae Is Regulated by Glucose
... to transcriptional acti- However, Std1 and Mth1 have only partially overlapping vation by ...abolish transcriptional activation, suggesting that is required for DNA binding by Rgt1 and inhibits phos- ...
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Engineering metabolite-responsive transcriptional factors to sense small molecules in eukaryotes: current state and perspectives
... Repression-based transcriptional regulation is rare in eukaryotic cells, a transcriptional activation domain is generally required to translate a bacteria repressor to a MRTF sensor in eukaryotic ...
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Plasmodium falciparum Histone Acetyltransferase, a Yeast GCN5 Homologue Involved in Chromatin Remodeling
... yeast transcriptional coactivator GCN5 (yGCN5), a histone acetyltransferase (HAT), is part of large multimeric complexes that are required for chromatin remodeling and transcriptional ...
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The EBNA1 Protein of Epstein-Barr Virus Functionally Interacts with Brd4
... tional activation without affecting other EBNA1 functions (45, ...through transcriptional activation ...both transcriptional activation and segregation in human cells ...
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