Transcriptional activation domains
Transcriptional Activation Domains of the Candida albicans Gcn4p and Gal4p Homologs
... transcription activation domains of the ...Gal4p activation domains do not share sequence similarity either to each other or to the activation domains of their ...nucleophilic ...
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Mutations in the DNA-binding and transcriptional activation domains of v-Myb cooperate in transformation.
... and transcriptional activation domains of v-Myb are required to prevent expression of C/EBP and Mim-1 in pri- mary transformed ...mutant domains (AAA and ...
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Identification, Mutational Analysis, and Coactivator Requirements of Two Distinct Transcriptional Activation Domains of the Saccharomyces cerevisiae Hap4 Protein
... Eukaryotic transcriptional activator proteins are typically bipartite in nature, with separable domains for DNA binding and transactivation (49, ...73). Transcriptional activation do- mains ...
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Identification of two independent transcriptional activation domains in the Autographa californica multicapsid nuclear polyhedrosis virus IE1 protein.
... eliminated transcriptional activation but did not affect binding to hr ...and domains required for nuclear local- ization have not yet been ...fected transcriptional activation) removed ...
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How the Rgt1 Transcription Factor of Saccharomyces cerevisiae Is Regulated by Glucose
... to transcriptional acti- However, Std1 and Mth1 have only partially overlapping vation by ...abolish transcriptional activation, suggesting that is required for DNA binding by Rgt1 and inhibits phos- ...
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Mechanisms of Inhibition of Nuclear Hormone Receptor-Dependent Hepatitis B Virus Replication by Hepatocyte Nuclear Factor 3β
... the transcriptional activation domains of this polypeptide (32, ...amino-terminal transcriptional activation domain of HNF3 (32, 33) was shown to be primarily respon- sible for ...
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Retroviral insertional activation in a herpesvirus: transcriptional activation of US genes by an integrated long terminal repeat in a Marek's disease virus clone.
... MDV, where the vast majority of the stable LTR insertions are localized (15). This finding has now been corroborated by at least two other studies involving coinfection of HVT or MDV with avian leukosis virus (8a, 13). ...
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The Chromatin and Transcriptional Landscape of Native Saccharomyces cerevisiae Telomeres and Subtelomeric Domains
... ABSTRACT Saccharomyces cerevisiae telomeres have been a paradigm for studying telomere position effects on gene expression. Telomere position effect was first described in yeast by its effect on the expression of reporter ...
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Transcriptional Activation of Human GD3 Synthase (hST8Sia I) Gene In curcumin-Induced Autophagy in A549 Human Lung Carcinoma Cells
... investigate transcriptional activation of hST8Sia I associated with autophagy formation in curcumin-treated A549 cells, functional characterization of the 5’-flanking region of the hST8Sia I gene was ...
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The hyper-activation of transcriptional enhancers in breast cancer
... Then, we took the groups of tumor H3K4me3 enhancers and analyzed their modifications and related gene tran- scription. The H3K4me3 super-enhancers showed higher H3K4me3 level in tumor than that in normal tissues, and so ...
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Effects of Wnt3A and mechanical load on cartilage chondrocyte homeostasis
... mechanical activation of b -catenin signalling has been reported in the colon of APC 1638N/+ mice [26], mesenchymal stem cells [27] and periodontal ligament cells ...the activation of this pathway resulting ...
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Epstein-Barr virus EBNA3A and EBNA3C proteins both repress RBP-J kappa-EBNA2-activated transcription by inhibiting the binding of RBP-J kappa to DNA.
... EBNA2 transcriptional activation is mediated by RBP-J k , it was necessary to determine if EBNA3A and EBNA3C would downregulate EBNA2-mediated activation from a thymidine kinase (TK) promoter ...
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Brd4-Independent Transcriptional Repression Function of the Papillomavirus E2 Proteins
... RNAPII-dependent transcriptional elongation through its interaction with pTEFb (37, ...in transcriptional regulation might depend on the acetylation status of cellular ...
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Transcriptional activation and dimerisation properties of oestrogen receptor β
... um transcriptional activity (Danielian et al 1992) that m ay reflect th eir in teractio n (M clnerney e t al ...of transcriptional activity produced by dom inant positive Ras (Trem blay et al ...little ...
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Asymmetry between activation and deactivation during a transcriptional pulse
... scriptional activation occurs predominantly as a single switch, whereas deactivation occurs with graded, stepwise decreases in transcription ...defined transcriptional states. Our findings reveal transcrip- ...
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dCas9-mediated transcriptional activation of tissue inhibitor of metalloproteinases
... gene activation with the dCas9 (deactivated clustered regularly interspaced short palindromic repeats [CRISPR] associated protein 9)/CRISPR targeting of a transcriptional activator effector is now well ...
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The JC virus minimal core promoter is glial cell specific in vivo.
... higher activation of the JCV minimal core promoter in Tst-1-deficient glial cells than in non-glial HeLa ...optimum activation of the JCV minimal core promoter by ...
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Molecular mechanism of transcriptional activation by oestrogen receptor alpha
... GR activation of a chromosomally integrated reporter gene, under the control of the m ouse m am m ary tum our virus (MMTV) prom oter requires the hSW I/SN F complex (Fryer and Archer, ...in transcriptional ...
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In Vivo Transcriptional Activation Using CRISPR/Cas9 in Drosophila
... Snail activation alone, consistent with the observation that these factors act syner- gistically (Rembold et ...to activation, was observed in a substantially higher proportion of Snail-regulated genes than ...
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Transcriptional activation of USP16 gene expression by NFκB signaling
... NFκB signaling pathway plays an important role in the gene regulation [23–25] and is associated with inflam- mation [26], oxidative stress [27], and apoptosis [28]. The mammalian NFκB family consists of five members, ...
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