Transfusion dependent thalassemia
Iron chelation therapy in transfusion-dependent thalassemia patients: current strategies and future directions
... Abstract: Transfusional iron overload is a major target in the care of patients with transfusion- dependent thalassemia (TDT) and other refractory anemias. Iron accumulates in the liver, heart, and ...
13
Prevalence of Alloantibodies and Autoantibodies in Transfusion Dependent Thalassemia Patients
... and transfusion informations of 110 transfusion dependent thalassemia patients (range: 10-35 years) who received regular transfusions were ...The transfusion informations of all ...
6
Increased mitochondrial DNA deletions and copy number in transfusion-dependent thalassemia
... with transfusion-dependent thalassemia (n = 38) and healthy con- trols (n = 24) were enrolled in the ...for thalassemia group and ...the thalassemia group are described in Table ...
11
Association of vitamin D deficiency and bone mass with liver and heart iron overload in transfusion dependent thalassemia
... Transfusion dependent Thalassemia patients were enrolled from Thalassemia Day Care centre at a Tertiary Care Teaching Hospital. Patients were enrolled from January 2019 to December 2019 who ...
5
Study of Prevalence of Hypoparathyroidism in Transfusion Dependent Thalassemia Patients Attending a Tertiary Care Hospital in West Bengal, Eastern India
... Hypoparathyroidism is one of the most common endocrine manifestations in transfusion dependent thalassemia. In our study mean age of hypoparathyroid patients was 15.82±2.76 years, similar studies ...
6
Remarkable Efficacy of Vitamin D in Improving Ventricular Dysfunction in Transfusion-Dependent Thalassemia Patients
... In thalassemia patients, clinical symptoms of vitamin D deficiency are often mistaken for the symptoms of chronic anemia or complications of iron- overload treatments ...in transfusion- dependent ...
10
<p>Prevalence of abnormal glucose homeostasis in Chinese patients with non-transfusion-dependent thalassemia</p>
... Purpose: To determine the prevalence and underlying pathology of abnormal glucose homeostasis in Chinese patients with non-transfusion-dependent thalassemia (NTDT). Patients and methods: In this ...
12
Prevalence of endocrine complications in transfusion dependent thalassemia in Hospital Pulau Pinang: A pilot study
... Table IV shows the results of certain variables in relation to development of endocrine complications among patients with transfusion dependent thalassemia. Patients with endocrine complications in ...
5
Assessment of Organ Specific Iron Overload in Transfusion-dependent Thalassemia by Magnetic Resonance Imaging Techniques
... years, kidney MRI has become a non-invasive, accurate ad specific method for detection of iron overload in transfusion dependent thalassemia. Both methods, MRI gradient echo (T2*) and spin echo (T2) ...
8
Reducing the iron burden and improving survival in transfusion-dependent thalassemia patients: current perspectives
... blood transfusion regimens have added decades to the lives of patients, clinicians are now faced with increasingly complicated management ...in transfusion-dependent thalassemia patients can ...
11
Profile of deferasirox for the treatment of patients with non-transfusion-dependent thalassemia syndromes
... Abstract: It has been clearly shown that iron overload adds progressively significant morbidity and mortality in patients with non-transfusion-dependent thalassemia (NTDT). The lack of physiological ...
8
Physical growth in children with transfusion-dependent thalassemia
... PRBC transfusion, age at starting iron chelation therapy, efficacy of the iron chelation drug and its compli- ance, and the age group of the reported series of ...11–19-year-old transfusion-dependent ...
7
Gingival health status among patients with transfusion dependent thalassemia (TDT) in Erbil city
... Methods: In this case control study, 50 transfusion dependent thalassemic patients aged 12 to 24 years compared with 50 healthy control subjects matching in age and sex. At be- ginning both beta thalassemic ...
6
SAFETY AND EFFICACY OF INTERFERON ALFA FOR THE TREATMENT OF CHRONIC HEPATITIS C INFECTED SUBJECTS WITH TRANSFUSION DEPENDENT THALASSEMIA IN IRAN
... The study took place in Tehran Adult Thalassemic Clinic, which serves over 500 adult patients with trans fusion dependent thalassemia. Subjects were included in the study if they met the following ...
10
Comparison of echocardiographic (US) volumetry with cardiac magnetic resonance (CMR) imaging in transfusion dependent thalassemia major (TM)
... homozygous, transfusion dependent tha- lassemia (TM) exhibit a broad spectrum of cardiac pathol- ogy due to the nature of their ...in thalassemia major and estimate the extent of ...
6
In Transfusion-dependent Thalassemia, Increased Iron Overload is Associated with Lower Serum Alpha-klotho, Which is Strongly Associated with Lower Total and Ionized Calcium Concentrations
... This study recruited 90 participants, namely 30 healthy controls and 60 TDT children, aged 3-12 years old and of both sexes. The TDT patients were recruited at the Thalassemia Unit at Al-Zahra'a Teaching Hospital, ...
31
Reproductive behavior in carrier couples for transfusion-dependent thalassemia major: evaluation of knowledge, attitude and practice
... Methods: This case-control study was conducted 327 carrier couples for thalassemia minor. Contact information of the couples was obtained from three healthcare centers randomly selected from the eastern, central ...
8
<p>Correlation of Cardiac and Liver Iron Level with T2*MRI and Vitamin D3 Serum Level in Patients with Thalassemia Major</p>
... blood transfusion- dependent thalassemia patients were examined, the mean Vitamin D3 serum levels were ...between thalassemia syndrome and vitamin D de fi ciency was found in 361 patients, ...
5
Blood Chemistry (Hematology) of Transfusion Dependent Beta Thalassemia Patients at Hyderabad and Adjoining Areas
... Present study was carried out to analyze quantitatively the blood parameters of Transfusion Dependent Thalassemia (TDT) patients. A total number of seventy one (n=71) TDT patients aged 04 to 26 years ...
5
Treatment Status of Patients with Β-Thalassemia Major in Northern Iran: Thalassemia Registry System
... the thalassemia center of Sari (north of Iran) indicates an increase in the average age of patients ...in transfusion-dependent ...non- transfusion-dependent ...frequent ...
11