transient receptor potential vanilloid receptor 1
A Novel Mechanism for Calmodulin Dependent Inactivation of Transient Receptor Potential Vanilloid 6
... Our twoAtail model hinges on the charging of the CaM NAlobe as the crucial Ca 2+ Asensing step with the CAtails not fully charged with CaM under basal Ca 2+ conditions, i.e. dependent on the local availability of the ...
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Transient Receptor Potential Vanilloid 1 Immunoreactive Innervation Increases in Fractured Rat Femur
... Animals were anesthetized with sodium pentobarbital (40 mg/kg, i.p.) and treated aseptically throughout the experi- ments. An incision of approximately 6 mm was made in the skin, then the proximal patellar ligament of ...
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Implication of Transient Receptor Potential Vanilloid Type 1 in 14,15-Epoxyeicosatrienoic Acid-induced Angiogenesis
... USA), 1 µg/ml hydrocortisone, 10 ng/ml human epidermal growth factor, 3 ng/ml human fibroblast growth fac- tor, 10 µg/ml heparin, and 1% antibiotic-antimycotic mixture (GibcoBRL, Grand Island, NY, ...a ...
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Retinoids activate the irritant receptor TRPV1 and produce sensory hypersensitivity
... native transient receptor potential channel vanilloid subtype 1 (TRPV1), an irritant receptor for capsaicin, the pungent ingredient of chili ...ionotropic receptor for ...
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Interaction Between the Cannabinoid and Vanilloid Systems on Anxiety in Male Rats
... Transient receptor potential vanilloid-1 (TRPV1) recep- tor is a subfamily of vanilloid family (Morales-Lazaro Si- mon, & Rosenbaum, ...the vanilloid system on the ...
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Implication of AMP-Activated Protein Kinase in Transient Receptor Potential Vanilloid Type 1-Mediated Activation of Endothelial Nitric Oxide Synthase
... with 1 μmol/L evodiamine for 15 min increased the interaction of AMPK with TRPV1 and eNOS, and TRPV1 with eNOS (Figures 5A, ...for 1 h or transfected with dnAMPK mutant (K45R) for 24 h, then incubated with ...
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Preventive Effect of SA13353, a Novel Transient Receptor Potential Vanilloid 1 Agonist, on Ischemia/Reperfusion Induced Renal Injury in Rats
... Ischemic cell injury in the kidney occurs during cardiovascular surgery, shock, and transplantation, which may lead to acute kidney injury (AKI). In an international investigation of the epidemiology of AKI, the period ...
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Forsythoside A exerts antipyretic effect on yeast-induced pyrexia mice via inhibiting transient receptor potential vanilloid 1 function
... Transient receptor potential vanilloid 1 (TRPV1) is a non-selective cation channel gated by noxious heat, playing major roles in ...
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Capsazepine, a Transient Receptor Potential Vanilloid Type 1 (TRPV1) Antagonist, Attenuates Antinociceptive Effect of CB1 Receptor agonist, WIN55,212-2, in the Rat Nucleus Cuneiformis
... TRPV1 receptor is activated by heat and capsaicin (Caterina et al., 1997). Other activators of TRPV1 re- ceptors are cannabinoids (Jeske et al., 2006). Electro- physiological and behavioral studies have provided ...
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Original Article Upregulation of the transient receptor potential vanilloid 1 in colonic epithelium of patients with active inflammatory bowel disease
... Inflammatory bowel disease (IBD), comprised of ulcerative colitis (UC) and Crohn’s disease (CD), is a group of chronic idiopathic disorders that is characterized by recurrent and remitting inflammation in ...
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Expression of transient receptor potential vanilloid (TRPV) channels in different passages of articular chondrocytes
... Chondrocyte lysates were collected from different passages including P0, and serial passages 1–3 (P1–3). Proteins were separated by SDS-PAGE and electroblotted as described in the Experimental Section. ...
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Transient receptor potential (TRP) gene superfamily encoding cation channels
... In humans, 27 different TRP genes are grouped into six different subfamilies based on their amino acid homologies (Table 1). The nomenclature of the TRP superfamily has been evolving for many years. Many genes and ...
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Post-transcriptional regulation of 5’-untranslated regions of human Transient Receptor Potential Vanilloid type-1 (TRPV-1) channels: role in the survival of glioma patients
... In conclusion our results, showing that the TRPV1 v3 has the lowest free energy in its secondary 5’UTR structure and the highest 5’UTR sequence stability, suggest that it may represent a potential prognostic ...
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Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... 32.9 (19.9-54.3), 219 (144-246) µM]. U266B1 cells were more resistant to CAP- induced death than THP-1 and U937 cells. TRPV1 and CB1 antagonists (SB452533 and AM251, respectively) suppressed the CAP-induced ...
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Transient receptor potential Vanilloid 1 (TRPV1) in haematological malignancies
... reported to be devoid of TRPV1 and then used as negative controls were in fact found to express TRPV1. Thus, untransfected and TRPV1-transfected (tetracycline off, which switches TRPV1 transcription off) HEK293 and ...
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Paeoniflorin protects diabetic mice against myocardial ischemic injury via the transient receptor potential vanilloid 1/calcitonin gene-related peptide pathway
... As shown in Fig. 1a, infarct size in mice treated with 70 or 140 mg/kg of PF for 14 days was smaller, compared with mice in the WTDM group. Although there was no statistical difference between the PF-WTDM-L and WTDM ...
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TRPA1 and other TRP channels in migraine
... of transient receptor potential (TRP) channels in health and disease has steadily ...TRP vanilloid 1 (TRPV1) and the TRP ankyrin 1 (TRPA1) are expressed in nociceptive neurons, ...
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Abundant expression and functional participation of TRPV1 at Zusanli acupoint (ST36) in mice: mechanosensitive TRPV1 as an “acupuncture responding channel”
... The transient receptor potential vanilloid receptors 1 and 4 (TRPV1 and TRPV4) and the acid-sensing ion channel 3 (ASIC3) are mechanosensi- tive channels related to local ATP release in ...
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Lack of transient receptor potential vanilloid 1 channel modulates the development of neurogenic bladder dysfunction induced by cross-sensitization in afferent pathways
... protein-coupled receptor stimulation and activate smooth muscle by changing potassium equilibrium poten- tial and triggering membrane depolarization (reviewed in ...
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THE ROLE OF TRANSIENT RECEPTOR POTENTIAL VANILLOID 1 RECEPTOR IN DESIPRAMINE INDUCED ANALGESIC EFFECT IN DIABETIC MICE
... INTRODUCTION: Antidepressants are widely used in chronic pain states including both inflammatory and neuropathic pain conditions. It has been suggested that antidepressant drugs have specific analgesic properties, and ...
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