Transmissible gastroenteritis coronavirus
Sialic Acid Binding Activity of Transmissible Gastroenteritis Coronavirus Affects Sedimentation Behavior of Virions and Solubilized Glycoproteins
... Transmissible gastroenteritis coronavirus (TGEV) is a pro- totype enteropathogenic coronavirus that causes diarrhea in pigs of all ages. While adult animals usually recover, newborn piglets ...
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Detection of swine transmissible gastroenteritis coronavirus using loop mediated isothermal amplification
... Swine Transmissible Gastroenteritis Coronavirus (TGEV), as a member of the coronaviridae, is a kind of single-stranded RNA virus, which produces villous atro- phy and enteritis, leading to the ...
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UBXN1 interacts with the S1 protein of transmissible gastroenteritis coronavirus and plays a role in viral replication
... Transmissible gastroenteritis coronavirus (TGEV) is an enteropathogenic coronavirus that causes diarrhea in pigs and is associated with high morbidity and mortality in sucking ...
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Identification of a Gamma Interferon Activated Inhibitor of Translation Like RNA Motif at the 3′ End of the Transmissible Gastroenteritis Coronavirus Genome Modulating Innate Immune Response
... the transmissible gastroenteritis coronavirus (TGEV) ge- nome was found to specifically interact with the host proteins glutamyl-prolyl-tRNA synthetase (EPRS) and arginyl-tRNA syn- thetase ...
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The Viral Nucleocapsid Protein of Transmissible Gastroenteritis Coronavirus (TGEV) Is Cleaved by Caspase-6 and -7 during TGEV-Induced Apoptosis
... The transmissible gastroenteritis coronavirus (TGEV), like many other viruses, exerts much of its cytopathic effect through the induction of apoptosis of its host ...
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The transmissible gastroenteritis coronavirus contains a spherical core shell consisting of M and N proteins.
... Coronaviruses are enveloped RNA viruses involved in a variety of pathologies that affect animals and humans. Existing structural models of these viruses propose a helical nucleocapsid under the virion envelope as the ...
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Binding of Transmissible Gastroenteritis Coronavirus to Cell Surface Sialoglycoproteins
... Transmissible gastroenteritis coronavirus (TGEV) is an en- teropathogenic coronavirus that causes diarrhea in pigs. While older animals generally recover, piglets under the age of 3 weeks ...
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Transmissible Gastroenteritis Coronavirus Genome Packaging Signal Is Located at the 5′ End of the Genome and Promotes Viral RNA Incorporation into Virions in a Replication-Independent Process
... of transmissible gastroenteritis coronavirus (TGEV) has been further delimited to the first 598 nucleotides (nt) from the 5= end of its RNA genome, by using recombinant viruses transcribing ...
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Generation of a Replication-Competent, Propagation-Deficient Virus Vector Based on the Transmissible Gastroenteritis Coronavirus Genome
... Transmissible gastroenteritis coronavirus (TGEV) is a mem- ber of the family Coronaviridae of the order Nidovirales ...a coronavirus genome comprises open reading frames 1a and 1b, containing ...
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Structural Maturation of the Transmissible Gastroenteritis Coronavirus
... the transmissible gastroenteritis coronavirus (TGEV), two types of virus-related particles are detected in infected swine testis cells: large annular viruses and small dense ...
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Stabilization of a Full-Length Infectious cDNA Clone of Transmissible Gastroenteritis Coronavirus by Insertion of an Intron
... full-length transmissible gastroenteritis coronavirus (TGEV) cDNA in Esche- richia coli cells as a bacterial artificial chromosome has been considerably improved by the insertion of an intron to ...
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The sialic acid binding activity of the S protein facilitates infection by porcine transmissible gastroenteritis coronavirus
... TGEV is a porcine coronavirus that causes diarrhea in pigs of all ages [2]. Piglets even die from the infection unless they are protected by maternal antibodies. This enveloped virus with a positive-stranded RNA ...
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Organization of Two Transmissible Gastroenteritis Coronavirus Membrane Protein Topologies within the Virion and Core
... The existence of a population of M molecules adopting a Nexo-Cexo topology in the virion envelope was demonstrated by i immunopurification of 35S-labeled TGEV virions using monoclonal an[r] ...
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Entry and release of transmissible gastroenteritis coronavirus are restricted to apical surfaces of polarized epithelial cells.
... To determine if the entry of TGEV in LLC-PK1 cells is restricted to a specific membrane domain, we analyzed virus-specific protein synthesis in filter-grown cells infected from the apica[r] ...
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In vitro inhibition of transmissible gastroenteritis coronavirus replication in swine testicular cells by short hairpin RNAs targeting the ORF 7 gene
... Transmissible gastroenteritis (TGE) is a highly conta- gious viral disease of swine, characterized by severe vomiting, diarrhea, and high mortality. These syndromes are especially serious in neonatal ...
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The Membrane M Protein Carboxy Terminus Binds to Transmissible Gastroenteritis Coronavirus Core and Contributes to Core Stability
... Transmissible gastroenteritis virus (TGEV) is a member of the Coronaviridae family and affects animals, causing severe illness (17, ...for coronavirus morphogenesis (5, 13, 18, ...drive ...
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Transmissible Gastroenteritis Coronavirus Induces Programmed Cell Death in Infected Cells through a Caspase-Dependent Pathway
... of coronavirus infections is poorly ...using transmissible gastroenteritis virus (TGEV) as a ...porcine coronavirus, replicates in the differentiated entero- cytes covering the intestinal ...
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Targeted Recombination Demonstrates that the Spike Gene of Transmissible Gastroenteritis Coronavirus Is a Determinant of Its Enteric Tropism and Virulence
... on coronavirus genome modifi- cation performed on the nucleoprotein gene of the murine hepatitis virus (MHV) (30, 38, 43, 62) or as described in the more-recent report on the replacement of the S gene of this ...
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Replication and Packaging of Transmissible Gastroenteritis Coronavirus-Derived Synthetic Minigenomes
... In MHV a defined packaging signal of 61 nt has been de- scribed (21). This sequence has been sufficient to pack a non- viral RNA encoding the chloramphenicol acetyl transferase (CAT) gene into virions (68). Nevertheless, ...
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Diagnosis of porcine and bovine enteric coronavirus infections using cloned cDNA probes
... Molecular clones representing the first 2,000 bases from the 3' end of the porcine transmissible gastroenteritis coronavirus genome and the first 2,160 bases from the 3' end of the bovin[r] ...
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