Tripartite motif (TRIM)
Tripartite Motif 8 Deficiency Relieves Hepatic Ischaemia/reperfusion Injury via TAK1-dependent Signalling Pathways
... Tripartite motif (Trim) 8 is an E3 ubiquitin ligase, interacting with and ubiquitinating diverse substrates, and is closely involved in innate ...
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Original Article Role of tripartite motif protein 27 as a gametogenesis-related protein in human germ cells
... the tripartite motif (TRIM) protein family are essential for cell proliferation, development and apoptosis, and TRIM proteins have been linked to various ...
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Original Article Tripartite motif 59 improves atherosclerotic vulnerable plaque stability of ApoE (-/-) mice by regulating the NF-κB signaling pathway
... Cardiovascular and cerebrovascular diseases are the leading cause of death in humans, and atherosclerosis (AS) is the pre-pathological basis for most cardiovascular and cerebrovas- cular diseases. The pathological ...
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The control of viral infection by tripartite motif proteins and cyclophilin A
... The control of retroviral infection by antiviral factors referred to as restriction factors has become an exciting area in infectious disease research. TRIM5α has emerged as an important restriction factor impacting on ...
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Isolation of an Active Lv1 Gene from Cattle Indicates that Tripartite Motif Protein-Mediated Innate Immunity to Retroviral Infection Is Widespread among Mammals
... (tripartite motif 5 ␣ ) has recently emerged as an important factor influencing species-specific permissivity to retroviral infection in a range of primates, including ...nonprimate TRIM protein, ...
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Tripartite motif-containing 3 (TRIM3) inhibits tumor growth and metastasis of liver cancer
... family. Tripartite motif (TRIM) proteins constitute a sub- family of the RING-type E3 ...all TRIM pro- teins have a RING domain, one or two B-box domains, and a coiled-coil domain [12, ...of ...
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Tripartite motif-containing 14 (TRIM14) promotes epithelial-mesenchymal transition via ZEB2 in glioblastoma cells
... follows: Tripartite motif-containing 14 (TRIM14): 5′-GCAGAAACTCAGCCAAGAA-3′ and 5′-CTTGACTCTGCATTAGCCT-3′, Zinc finger E-box binding homeobox 2 (ZEB2): 5′-GGCGCAAACAAGCC AATCCCA-3′ and ...
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Original Article Tripartite motif-containing protein 37 is overexpressed in human glioma and its downregulation inhibits human glioma cell growth in vitro
... solved. Tripartite motif-containing protein 37 (TRIM37) is an E3 ubiquitin ligase that may be involved in the tumorigenesis of several types of cancer; however, its expression pattern and biological ...
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Role of the Tripartite Motif Protein 27 in Cancer Development
... Figure 1 . The tripartite motif family protein 27 ( TRIM27 ) expression in human and mouse cancer. A and B ) TRIM27 expression was assessed using Clontech cancer- profi ling arrays containing 261 paired ...
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Original Article Tripartite motif-containing protein 33 (TRIM33) negatively regulates amyloid-β production by promoting proteasome-dependent degradation of BACE1
... Tripartite motif-containing 33 (TRIM33) is a member of the tripartite motif superfamily that possess a RING domain, two B-boxes, and a coiled-coil domain at the N-terminus as well as a plant ...
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miR-182 promotes tumor growth and increases chemoresistance of human anaplastic thyroid cancer by targeting tripartite motif 8
... Abstract: Chemotherapy is one of the most effective forms of cancer treatment and has been used in the treatment of various malignant tumors. We have gained significant insight into the mechanisms of chemoresistance but ...
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Human Tripartite Motif 5α Domains Responsible for Retrovirus Restriction Activity and Specificity
... Replacement of a small segment of huTRIM5 ␣ in the B30.2/ SPRY domain confers potent anti-HIV-1 activity. Of the TRIM5 ␣ variants in primates characterized thus far, several have broad antiretroviral activity, and only ...
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Tripartite Motif Containing 9 as a Novel Innate Immune Response Gene and Mediator of Macrophage Migration.
... In a screen of larval zebrafish for innate immune response genes, we identified tripartite motif 9 ( trim9 ) as a gene with increased transcript levels in response to the immune agoni[r] ...
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Comparative Analysis of Tripartite Motif Containing 9 Protein Expression in Macrophages and Neutrophils.
... 85 literature. TRIM5 auto-ubiquitylates itself, inducing proteasomal degradation, and results in high TRIM5 protein turnover 21 . Fletcher et al. hypothesize this is a form of negative regulation that allows TRIM5 to be ...
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Functional Replacement of the RING, B-Box 2, and Coiled-Coil Domains of Tripartite Motif 5α (TRIM5α) by Heterologous TRIM Domains
... human TRIM paralogs on chromosome 11 is composed of TRIM6, TRIM34, TRIM5, and ...these TRIM proteins, only TRIM5 ␣ exhib- ited inhibitory activity with respect to HIV-1 or N-MLV infec- ...
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TRIM52 promotes colorectal cancer cell proliferation through the STAT3 signaling
... RNA; TRIM: tripartite motif; NS2A: nonstructural protein 2A; JEV: Japanese encephalitis virus; HCC: hepatocellular carcinoma; HBX: hepatitis B virus X protein; IHC: immunohisto- chemistry; shRNAs: ...
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General Model for Retroviral Capsid Pattern Recognition by TRIM5 Proteins
... the tripartite motif) that precede the capsid-binding domains (11, ...hexagonal TRIM net wraps about the capsid and arranges the associated SPRY domains to match the arrangement of the CA subunits on ...
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Capsid Proteins from Human Immunodeficiency Virus Type 1 and Simian Immunodeficiency Virus SIVmac Can Coassemble into Mature Cores of Infectious Viruses
... the tripartite motif-containing fam- ily of proteins ...The tripartite motif comprises a RING domain that includes two zinc finger motifs, one or two B-box domains, and a coiled-coil domain ...
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Capacity Testing and Local Flow Analysis of a Geometrically Complex Trim Installed within a Commercial Control Valve
... Advanced CFD tools have proven to be extremely powerful design tools and in- creasingly being incorporated into the design stage for many different products [2, 3, 4, 5]. CFD allows for the testing of various designs ...
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Articles
... and Tripartite; Morales-Briones et al. 2018a). Given its tripartite leaf and glomerulate inflorescence (see Taxonomic treatment for details), ...the Tripartite clade, but we were not able to obtain ...
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