Tubulointerstitial Nephritis
Simultaneous occurrence of IgG4-related Tubulointerstitial nephritis and colon adenocarcinoma with hepatic metastasis: a case report and literature review
... For evaluation of renal dysfunction, a renal biopsy was performed. The pathological findings in light microscopy demonstrated glomerular sclerosis in two of twelve glomeruli whereas the other glomeruli demonstrated only ...
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Urinary β2-microglobulin and disease activity in patients with tubulointerstitial nephritis and uveitis syndrome
... Tubulointerstitial nephritis and uveitis (TINU) syndrome is a rare, idiopathic inflammatory disorder characterized by acute tubulointerstitial nephritis (TIN) and uveitis without an otherwise ...
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Acute tubulointerstitial nephritis complicating Legionnaires' disease: a case report
... pneumonia complicated by acute renal failure. Legionella pneumophila serogroup type 1 was diagnosed. Although the patient ’ s respiratory illness responded to intravenous erythromycin and ofloxacin therapy, his renal ...
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A Case of Acute Renal Failure Associated with IgG4 Related Disease Presenting Both Tubulointerstitial Nephritis and Retroperitoneal Fibrosis
... We report a case of IgG4-related disease presenting both tubulointerstitial nephritis and retroperitoneal fibrosis causing acute renal failure in a 63-year-old male. He was admitted to our hospital because ...
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Drug-induced tubulointerstitial nephritis in a retrospective study using spontaneous reporting system database
... Introduction: Tubulointerstitial nephritis (TIN) is a problem in clinical settings because drug therapy is the cause in most cases. Patients often present with nonspecific symptoms, which can lead to delays ...
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Tubulointerstitial nephritis antigen-like 1 protein is downregulated in the placenta of pre-eclamptic women
... Tubulointerstitial nephritis antigen-like 1 protein (TIN- AGL1) also known as Lipocalin 7 (LCN7) or adreno- cortical zonation factor-1 (AZ1) or tubulointerstitial nephritis antigen related ...
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Vitamin C induced hyperoxaluria causing reversible tubulointerstitial nephritis and chronic renal failure: a case report
... Since urinalysis was negative and proteinuria was mini- mal, oxalate-induced tubulointerstitial nephritis was pro- posed, given history of alcoholism, chronic diarrhea, and high-dose vitamin C. On day 2, ...
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Inhibitory role of dietary protein restriction on the development and expression of immune mediated antitubular basement membrane induced tubulointerstitial nephritis in rats
... The protective effect of dietary protein restriction on the development and expression of immune-mediated interstitial nephritis was evaluated in Brown Norway rats with anti-tubular basement membrane disease. In ...
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Tubulointerstitial nephritis and uveitis (TINU) syndrome: a systematic review of its epidemiology, demographics and risk factors
... with tubulointerstitial nephritis without uveitis; this uveitis cohort was also associated with HLA-DRB1*08 (RR = ...interstitial nephritis, again rais- ing the possibility that some of these alleles ...
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Tubulointerstitial nephritis with monotypic lympho-plasmacytic infiltrates in a patient with primary Sjögren’s syndrome accompanied by IgA-type monoclonal gammopathy
... Case presentation: A 74-year-old Japanese woman with pSS who had been diagnosed as having IgA kappa-type MGUS developed progressive renal dysfunction. Renal biopsy revealed tubulointerstitial nephritis with ...
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A case of severe osteomalacia caused by Tubulointerstitial nephritis with Fanconi syndrome in asymptomotic primary biliary cirrhosis
... 6]. Tubulointerstitial nephritis (TIN) and subsequent Fanconi syndrome, a type of proximal tubular defects, have been more rarely reported in patients with PBC ...
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Tubulointerstitial nephritis in primary Sjögren syndrome: clinical manifestations and response to treatment
... GFR: Glomerular Filtration Rate; eGFR: estimated Glomerular Filtration Rate; Cr-GFR: Chromium-51 labeled ethylenediamine tetraacetic acid measured GFR; IgG: immunoglobulin G; IQR: Interquartile range; LSGs: Labial ...
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Nephrotoxicity of immune checkpoint inhibitors beyond tubulointerstitial nephritis: single-center experience
... acute tubulointerstitial nephritis, RRT renal replacement therapy, GPA granulomatosis with polyangiitis, PR3 proteinase 3, ANCA antineutrophil cytoplasmic antibodies, MPO myeloperoxidase, N/A not available, ...
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Cilostazol-induced acute tubulointerstitial nephritis accompanied by IgA nephropathy: a case report
... for differentiating ATIN from acute tubular necrosis [3, 14]. If a patient has glomerulonephritis, its interpretation is not conclusive but supportive of tubulointerstitial changes in the kidney. Hematuria is a ...
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IgG4-related tubulointerstitial nephritis accompanied with cystic formation
... Based on pathological results after surgery, then we ana- lyzed stored preoperative serum retrospectively. As a result, the patients had hypocomplementemia and poly- clonal gammopathy with elevated levels of serum IgG ...
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Development of experimental model of chronic pyelonephritis with Escherichia coli O75:K5:H bearing Dr fimbriae: mutation in the dra region prevented tubulointerstitial nephritis
... Escherichia coli that express Dr fimbriae and related adhe- sins recognize the common receptor decay accelerating fac- tor. E. coli strains that express adhesins of the Dr family were postulated to be associated with ...
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A case of IgG4-related tubulointerstitial nephritis concurrent with Henoch-Schönlein purpura nephritis
... diffuse tubulointerstitial nephritis (TIN); and 3) renal lesions composed of focal lymphoplasmacytic infiltration of the renal interstitium ...HSP nephritis that was complicated by IgG4-related ...
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Unusual manifestations of acute Q fever: autoimmune hemolytic anemia and tubulointerstitial nephritis
... Q fever is a worldwide zoonotic infection that caused by Coxiella burnetii, a strict intracellular bacterium. It may be manifested by some of the autoimmune events and is classified into acute and chronic forms. The most ...
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Immune checkpoint inhibitor (nivolumab)-associated kidney injury and the importance of recognizing concomitant medications known to cause acute tubulointerstitial nephritis: a case report
... pathway by ICPI therapy can result in ATIN by altering T-cell immune tolerance against concomitant drugs (drug- induced) or kidney intrinsic antigens (autoimmune related). The detailed mechanism underlying the induction ...
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Evaluation of diagnostic criteria for IgG4-related tubulointerstitial nephritis
... Results: Twelve high-probability IgG4-TIN were screened by histology, imaging, serology and other organ involvement according to the Mayo Clinic proposed criteria. The previous principal pathological diagnoses were IgAN ...
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