tumour necrosis factor-α
Commercially Available Antibodies to Human Tumour Necrosis Factor-α Tested for Cross-Reactivity with Ovine and Bovine Tumour Necrosis Factor-α using Flow Cytometric Assays
... human tumour necrosis factor- α tested for cross-reactivity with ovine and bovine tumour necrosis factor- α using flow cytometric ...treatments. Tumour ...
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Tumour necrosis factor-α/interleukin-10 ratio in patients with obstructive sleep apnoea hypopnoea syndrome
... Statistical analysis Data normality was analysed using the Kolmogorov –Smirnov test. Differences between the two groups were analysed using the unpaired t- test, Mann –Whitney U test or chi-square test, as indicated. ...
Immune complexes from rheumatoid arthritis synovial fluid induce FcγRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor α by peripheral blood mononuclear cells
... between tumour necrosis factor-α production and number of swollen and tender joints The amount of TNF-α produced after stimulation with SF pre- cipitates correlated with the number of ...
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Tumour Necrosis Factor-α (TNF-α) antagonists and Tuberculosis
... • Residual radiographic tuberculous lesions over 1cm 2 in size with no certainty that eradicative treatment was received. Chemoprophylaxis (to be commenced at least 3 weeks prior to commencing TNF-α antagonist) is ...
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Exogenous tumour necrosis factor α induces suppression of autoimmune arthritis
... of tumour necrosis factor (TNF)α in the recovery phase of adjuvant arthritis (AA), suggesting a correlation between high TNFα levels and reduced severity of ...
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Tumour necrosis factor-α production in fibrosing alveolitis is macrophage subset specific
... TNF- α pro- duction between AMs and peripheral blood monocytes probably reflects monocyte maturation and localised acti- ...TNF- α secretion and that a specific subset of mononuclear phagocytes, RFD7, was ...
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Real-life drug survival of tumour necrosis factor-α antagonists in inflammatory arthritis
... Drugs designed to inhibit TNF-α, known as TNF-α antagonists (or “anti-TNFs”), are an example of a relatively new class of drugs called biologic agents. These agents are so named because they are synthesized ...
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THE PRESENCE OF PERIODONTOPATHOGENS ASSOCIATED WITH THE TUMOUR NECROSIS FACTOR-α EXPRESSION IN PATIENTS WITH DIFFERENT PERIODONTAL STATUS
... actinomycetemcomitans caused periodontal tissue degradation and increased PD and CAL clinical parameters by a mechanism that does not involve the participation of pro-inflammatory cytokine TNF-α, whereas P. ...
Circulating tumour necrosis factor α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical response
... However, the improvement varied between patients. In an attempt to explain these differences between patients, we explored whether heterogeneity exists in the contribu- tion of circulating TNF-α bioactivity, with ...
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Tumour necrosis factor-α inhibitors for ankylosing spondylitis and non-radiographic axial spondyloarthritis: A systematic review and economic evaluation
... the life-time cost-effectiveness results. To avoid extrapolating life-time improvement by applying a functional form to the BASDAI/BASFI data, the manufacturer applied the mean observed BASDAI and BASFI scores until the ...
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Long-term effectiveness of tumour necrosis factor-α inhibitor treatment for psoriatic arthritis in the UK: A multicentre retrospective study
... Data on treatment pathways during the observation pe- riod (from initiation of first TNFi until data collection) in- cluded: TNFi therapy, duration of treatment for each different TNFi r[r] ...
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Inflammatory Cytokines Interleukin-1β and Tumour Necrosis Factor-α - Novel Biomarkers for the Detection of Periodontal Diseases: a Literature Review
... Since TNF-α plays a role in the development and maintenance of inflammatory diseases, its mediating effects on the development, progress, and maintenance of periodontal diseases would be expected to occur. Many ...
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Inhibition of established collagen induced arthritis with a tumour necrosis factor α inhibitor expressed from a self contained doxycycline regulated plasmid
... TNF- α inhibitors repre- sents a feasible and simple gene therapy approach for RA treatment and demands further improvements in gene reg- ulation and methods of ...
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Extracellular heat shock protein 70 inhibits tumour necrosis factor α induced proinflammatory mediator production in fibroblast like synoviocytes
... Conclusion In this study we demonstrate a novel role for exogenous human HSP70 in suppressing proinflammatory mediator pro- duction by human RA FLSs. The anti-inflammatory role played by human HSP70 in human RA FLSs may ...
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Mesenchymal stem cells exert anti-proliferative effect on lipopolysaccharide-stimulated BV2 microglia by reducing tumour necrosis factor-α levels
... We have also demonstrated here that MSC modulate the expression of TNF-α and IL-6. Co-culture with MSC significantly reduced the TNF-α which was upregulated upon LPS stimulation whereas co-culture induced a ...
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Association of tumour necrosis factor-α (TNF-α) gene polymorphisms (-308 G>A and -238 G>A) and the risk of severe dengue: a meta-analysis and trial sequential analysis
... protective effects against DHF/DSS [30]. It has been suggested that the interactions of TNF-α, IFN- γ and activated complement proteins enhance plasma leakage of endothelial cells in sec- ondary dengue infection ...
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Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis
... soluble tumour necrosis factor receptors (sTNFRs) are elevated in the circulation of patients with rheumatoid arthritis ...of tumour necrosis factor- α , levels of sTNFRs ...
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Polymorphism in the tumour necrosis factor receptor II gene is associated with circulating levels of soluble tumour necrosis factor receptors in rheumatoid arthritis
... soluble tumour necrosis factor receptors (sTNFRs) are elevated in the circulation of patients with rheumatoid arthritis ...of tumour necrosis factor- α, levels of sTNFRs ...
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Treatment of Hidradenitis Suppurativa with Tumour Necrosis Factor-a Inhibitors
... tory skin disease. Medical treatment is often disappoin ting and in severe disease surgery remains the therapy of choice. Extensive surgery may be effective but also mutilating. Patients experience a significant ...
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