Type I and V collagen
Type V collagen induces apoptosis of 8701 BC breast cancer cells and enhances m calpain expression
... selection" software available on-line. As shown in fig. 5A, the PCR amplification gave a product which displayed a size (512 bp) identical to that expected theoretically; moreover, to confirm its identity, the ...
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Anti-collagen type v: a marker of early systemic sclerosis?
... Collagen type V is a highly immunogenic extracellular matrix protein with preserved globular and telopeptide domains found inside heterotypic fibrils mixed with col- lagen types I and III ...
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Type-1 pericytes accumulate after tissue injury and produce collagen in an organ-dependent manner
... anti- collagen type I antibody (AbD Serotec, Raleigh, NC, USA) at 1:1,000 dilution) at room temperature for 4 hours and vi- sualized using appropriate species-specific secondary anti- bodies ...
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Non-invasive biomarkers derived from the extracellular matrix associate with response to immune checkpoint blockade (anti-CTLA-4) in metastatic melanoma patients
... of type III collagen [17], C1M is from MMP-degraded type I collagen [25], C3M is from MMP-degraded type III collagen [26], C4M is from MMP-degraded type IV ...
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Molecular and ultrastructural studies of a fibrillar collagen from octocoral (Cnidaria)
... for type I and II collagen (structure factors and phases) to determine the packing features of this plausibly novel class of collagen from ...
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Biochemical markers of bone collagen type I metabolism
... various collagen types (I, V, VI, XIV and XXIV) [12]. Collagen type I is the most abundant among proteins, making up 95% of the total bone collagen and 80% of the whole ...
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Lipocytes from normal rat liver release a neutral metalloproteinase that degrades basement membrane (type IV) collagen
... native type IV (basement membrane) collagen but not interstitial collagen types I or V and exhibits no activity against laminin or ...soluble collagen in vitro, it rapidly ...
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<p>Effect of Intracorporeal Human Adipose–Derived Stem Cells (hADSCs) on Corpora Cavernosa Transforming Growth Factor β1 (TGFβ1) and Collagen Type I Concentration in Wistar Rat Priapism Model</p>
... of collagen type III and α SMA), which might be useful in further characterizing fi brotic tissue composition and inhibi- tion by ...and collagen tissue assessment using PCR and Western blot would ...
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Lung collagen heterogeneity Synthesis of type I and type III collagen by rabbit and human lung cells in culture
... synthesizes type II collagen, it has been suggested that other collagen types are present in ...lung collagen type. To approach the problem of additional lung collagen ...
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Differences in glutamate receptors and inflammatory cell numbers are associated with the resolution of pain in human rotator cuff tendinopathy
... deparaffinisation and target retrieval steps using an auto- mated PT Link (Dako, Glostrup, Denmark). All antibody staining was performed using the EnVision FLEX™ visual- isation system with an Autostainer Link 48 (Dako) ...
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The Ehlers Danlos syndrome: on beyond collagens
... fibronectin type III repeats of TNX presented by Erickson suggests that these elements may undergo reversible unfolding and refolding ...of collagen fibrils and provide a flexible link between ...
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Type I collagen gene suppresses tumor growth and invasion of malignant human glioma cells
... Interestingly, type I collagen is a fibrillar collagen, whereas fragments of collagens, which have so far been reported to inhibit tumor progression, are derived from basement membrane ...
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LAP (NF IL6) transactivates the collagen alpha 1(I) gene from a 5' regulatory region
... Although collagen is known to enhance hepatocyte differentiation and hepatocytes produce collagen in vivo, the transcriptional factors responsible for collagen type I gene expression in ...
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Characterisation of the immune response to type I collagen in scleroderma
... This study was conducted to examine the frequency, phenotype, and functional profile of T lymphocytes that proliferate in response to type I collagen (CI) in patients with scleroderma (SSc). ...
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The trans-well coculture of human synovial mesenchymal stem cells with chondrocytes leads to self-organization, chondrogenic differentiation, and secretion of TGFβ
... SMSC were kept in monolayer cultures alone or in co- culture with CHDR. As a positive control, these cocul- tures were supplemented with TGFβ. While SMSC alone stayed separated after 1 week, an aggregation of SMSC was ...
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Diagnostic significance of biochemical indicators of liver fibrogenesis in adolescents with obesity
... serum type IV collagen (Serum collagen IV EIA, Argutus Medical (Japan)) in blood, N - terminal propeptides of type I collagen (NT-proCNP, Biomedica (Aus- tria)) and C-terminal ...
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Overexpression of Interleukin-18 Aggravates Cardiac Fibrosis and Diastolic Dysfunction in Fructose-Fed Rats
... Inflammation plays an important role in the pathophysiology of the metabolic syndrome (MS). We determined whether the overexpression of interleukin (IL)-18 could aggravate left ventricular (LV) remodeling and diastolic ...
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Diminished type I collagen synthesis and reduced alpha 1(I) collagen messenger RNA in cultured fibroblasts from patients with dominantly inherited (type I) osteogenesis imperfecta
... Type I osteogenesis imperfecta (OI) is characterized clinically by a moderate fracture frequency with minimal bone deformity and dominant ...of type I ...of type I ...1(I) ...
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Collagen and Collagen derived Fragments Are Chemotactic for Tumor Cells
... in collagen such as liver, lungs, and bone are frequently sites of tumor cell ...to collagen in ...the collagen helix caused similar ...that collagen or collagen fragments released ...
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Collagen types I and II distribution: a relevant indicator for the functional properties of articular cartilage in immobilised and remobilised rabbit knee joints
... in collagen type I and type II distribution in the articular cartilage of immobilised and remobilised rabbit knee ...3. Collagen type I and type II in the articular ...
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