Uterine Leiomyosarcoma
Original Article Constitutive activation with overexpression of the mTORC2 -phospholipase D1 pathway in uterine leiomyosarcoma and STUMP: morphoproteomic analysis with therapeutic implications
... in uterine leiomyosarcoma (ULMS) and smooth muscle tumors of un- certain malignant potential (STUMP) as evidenced by nuclear localization of p-mTOR (Ser 2448) in ULMS>STUMP>uterine leiomyoma ...
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miRNAs 144-3p, 34a-5p, and 206 are a useful signature for distinguishing uterine leiomyosarcoma from other smooth muscle tumors
... Uterine leiomyosarcoma (LMS) is a rare and extremely ag- gressive tumor that is characterized by poor prognosis, early dissemination, and high metastatic potential, even when LMS is confined to the ...
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Isolated cutaneous metastasis of uterine leiomyosarcoma: case report and review of literature
... advanced uterine leiomyosarcoma has been suggested by the Euro- pean Organization for Research and Treatment of Can- cer to have lower rates of local recurrence but no improvement in long term survival ...
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Pancreatic metastases originating from uterine leiomyosarcoma: a case report
... In this report, we describe the case of a 67-year-old woman with metastatic pancreatic uterine leiomyosarcoma. She underwent a total hysterectomy and adnexectomy in December 2009. The resected ...
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Original Article Activation of NPY1R increases the proliferation and invasion of human uterine leiomyosarcoma cells
... human uterine leiomyosar- coma cells, and NPY1R antagonist markedly decreased the proliferation and invasion, espe- cially in presence of NPY1R ...in uterine leiomyosar- ...
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Long lasting clinical response to chemotherapy for advanced uterine leiomyosarcoma: a case report
... underwent ten lines of chemotherapy, achieving excellent results and a good quality of life. Among the treatments administered we observed a long response to temolozomide, an unconventional drug for this kind of disease. ...
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Lockjaw from a metastatic uterine leiomyosarcoma- case report and review of the literature
... the uterine specimen demonstrated one fibroid measuring 70 mm diameter and showing an abnormal focal area and central cystic necrosis consist- ent with a low grade leiomyosarcoma surrounded by normal tissue ...
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Treatment of hormone positive uterine leiomyosarcoma with aromatase inhibitors
... AIs: Aromatase inhibitors; BSO: Bilateral salpingo-oophorectomy; CB: Clinical benefit; CBR: Clinical benefit rate (CR + PR + SD ≥ 6 months); CR: Complete response; CTCAE: Common Terminology Criteria for Adverse Events; ...
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Uterine leiomyosarcoma: A 10-year review in a referral hospital in Peru, 2005 - 2014
... In conclusion, uterine LMS is an extremely rare diagnosis with no clinical and imaging findings distinguishing it from the more usual leiomyoma. Diagnosis before any surgical intervention is only feasible in ...
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Malignant perivascular epithelioid cell tumor (PEComa) of the uterus with late renal and pulmonary metastases: a case report with review of the literature
... for uterine leiomyosarcoma (American Joint Commission on Cancer Staging; AJCC T1c N0 M0; diagnosed at an outside institu- tion) seven years prior presented to our institution for her regular periodic ...
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Original Article Clinical outcomes of undifferentiated sarcomas are similar with that of other spindle cell sarcomas of specific histologic types: an institutional experience
... carcinoma in the form of high sarcomatoid car- cinoma should be considered. In this case, use of wide range immunohistochemical panel con- taining several antibodies for the detection of epithelial differentiation may be ...
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FIGO Staging for Uterine Sarcomas: Can the Revised 2008 Staging System Predict Survival Outcome Better?
... was introduced as a staging variable in the revised FIGO staging system for uterine leiomyosarcoma and endometrial stromal sarcoma. In this new system, stage I disease is di- vided into IA or IB according ...
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Hyperkalemia and acute kidney failure associated with preoperative uterine artery embolization for a large uterine fibroid: a case report
... of uterine fibroids was first reported in 1995 [1], and since then, many reports [2–15] have described the risks and benefits of ...a uterine weight of more than 1000 g have a significantly higher risk of ...
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Gastric leiomyosarcoma and diagnostic pitfalls: a case report
... Gastrointestinal stromal tumours (GISTs) were con- sidered to be of smooth muscle origin. They were misdiagnosed as leiomyomas and leiomyosarcomas. Since the advent of immunohistochemistry for the diagnosis of stromal ...
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Leiomyosarcoma of Maxillary Sinus – A Rare Clinical Entity
... of leiomyosarcoma of the maxilla in a patient who sought treatment for maxillary swelling, nasal obstruction with no epistaxis, orbital involvement or cervical lymph node ...
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Leiomyosarcoma of the Duodenum in a 10-Year-Old Boy
... and normal delivery. He weighed 3.7 kg at birth, and had normal developmental parameters. In mid-October 1971 he developed abdominal pain followed by progressive weakness and exercise in[r] ...
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Uterine blood flow and uterine renin secretion
... between uterine blood flow and uterine renin secretion. Uterine blood flow was measured by the percentage distribution of radioactive microspheres injected into the left ventricle which lodged in ...
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Management of an Unusual Complication of Uterine Fibroids in the Gynecological Department of the University and Hospital Center of Treichville (Cote D’ivoire): About 2 Cases of Non Puerperal Uterine Inversion
... Mrs D K, a 34 years jobless woman, having 3 children born by cesarean section, consulted at the gynecological emergency unit in our service for a large mass ex- ternalized to the vulva. The history revealed intermittent ...
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Feasibility of uterine preservation in the management of early stage uterine adenosarcomas: a single institute experience
... We performed a retrospective review of patients with stage I uterine adenosarcoma diagnosed and treated at Asan Medical Center, Seoul, Korea, from 1998 to 2014. Medical records were reviewed for age at diag- ...
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Primary Leiomyosarcoma of the Ovary: A Case Report
... primary leiomyosarcoma of the ovary in which adjuvant treatment with ifosfamide and doxorubicin has been used, achieving progression-free survival at 24 months, and overall survival at 36 ...for ...
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