Vaccine candidates
Differing Efficacies of Lead Group A Streptococcal Vaccine Candidates and Full Length M Protein in Cutaneous and Invasive Disease Models
... GAS vaccine for human ...GAS vaccine candidates can be classified into two cat- egories, M-protein-based vaccines and non-M-protein-based ...lent vaccine approach, where the hypervariable ...
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Immunogenicity of Novel Mumps Vaccine Candidates Generated by Genetic Modification
... mumps vaccine, JL, is a mixture of at least two well-distinguished components ...during vaccine preparation and propagation has been proposed ...amplification. Vaccine candidates can be ...
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Comparative Evaluation of Two Hemagglutinating Encephalomyelitis Coronavirus Vaccine Candidates in Mice
... PHE-CoV vaccine candidates, the frequencies of cells producing IL-2, IL-4, TNF- ␣ , and IFN- ␥ at the single-cell level were determined using an ELISA ...five vaccine groups (IP, IPV, S1, 2S1 ⫹ IPV, ...
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Recombinant lipoprotein-based vaccine candidates against C. difficile infections
... difficile vaccine development is urgently needed to control the increasing incidence of hospital-acquired CDI that are responsible for rising medical ...as vaccine candidates represent a new ...
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Extracellular vesicles secreted by Schistosoma mansoni contain protein vaccine candidates
... described vaccine candidates or therapeutic agents (see Table ...mansoni vaccine can- didates or homologues of protective antigens from other ...
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Vaccine Candidates against Nontypeable Haemophilus influenzae: a Review
... investigating vaccine development have focused on the protectively area of the external membrane proteins, LOS, and ...various vaccine candidates have been developed with the immunogenicity of PD, ...
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Genetic Stability of Parainfluenza Virus 5-Vectored Human Respiratory Syncytial Virus Vaccine Candidates after In Vitro and In Vivo Passage
... RSV vaccine have been made for over 40 years, no licensed vaccine currently exists ...RSV vaccine candidates to date have been live attenuated or vectored ...RSV vaccine candidate, also ...
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Genetically engineered live attenuated influenza A virus vaccine candidates.
... The complete protection from challenge afforded by previ- ous infection with the wild-type virus, compared to the lower level of protection observed with the attenuated viruses, may be related to a higher level of ...
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Previously Unrecognized Vaccine Candidates Control Trypanosoma cruzi Infection and Immunopathology in Mice
... good vaccine candidates. In this study, we tested the vaccine efficacy of three of the putative candidate antigens against ...novel vaccine candidates that provided protection from ...
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Discovery of Common Putative Drug Targets and Vaccine Candidates for Mycobacterium tuberculosis sp.
... The experimental approaches are tedious and laborious obtain very few results hence computational approaches were used to identify the putative drug targets. Comparative proteomic approach, subtractive proteomic ...
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MalVac: Database of malarial vaccine candidates
... MalVac Database contains analysis data on 332 potential vaccine candidates on three most important Plasmodium species. Of these, 161 are from P. falciparum, 137 are from P. vivax and 34 are from P. yoelii. ...
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Characterization of transgene expression in adenoviral vector based HIV 1 vaccine candidates
... attractive candidates for prophylactic or therapeutic vaccine ...HIV-1 vaccine candidates based on adenovirus serotype 5 (Ad5) vectors in which the E1 gene, a critical component for adenovirus ...
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Large screen approaches to identify novel malaria vaccine candidates
... protective vaccine candidates. Identifying such candidates requires both the careful choice of input samples used for high throughput antibody or T cell based screening, as well as down- selection ...
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Assessment of vaccine candidates for persons aged 50 and older: a review
... formulated set of criteria for additions to a national immunization programme. Herpes zoster, pneumococcal disease and pertussis are common among persons aged 50 and older in the Netherlands, and in the future, this ...
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Synthesis and immunological evaluation of peptide-based vaccine candidates against malaria
... There are several drugs for the treatment of malaria nowa- days; however, Plasmodium parasites are becoming resistant to majority of these medicines. In addition, the most effective treatments are often too expensive for ...
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Improving in Silico Prediction of Epitope Vaccine Candidates by Union and Intersection of Single Predictors
... The epitope-based vaccines are a new generation of vac- cines which are very well tolerated and have fewer side effects than the conventional vaccines. The in silico pre- diction of peptide binding affinities to MHC ...
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Further exploration of nontypable Haemophilus influenzae proteins P5 and P6 as vaccine candidates
... immunosorbent assay (ELISA), that 4G4 and 7F3 compete for binding to P6 and thus share a similar or overlapping epitope while 3B9 has an independent binding site. Mapping of the epitope for 3B9 showed that its binding is ...
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Antibodies to malaria vaccine candidates are associated with chloroquine or sulphadoxine/pyrimethamine treatment efficacy in children in an endemic area of Burkina Faso
... vaccines are being produced and tested, the control of malaria relies heavily on chemotherapy[4,5]. Many of the available anti-malarial drugs are effective, cheap, and easy to distribute. However, in recent years, the ...
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Purification of PIA and rSesC as Putative Vaccine Candidates Against Staphylococcus aureus
... PIA has extensively been evaluated as a putative candid for vaccine development. When PIA is the major component of the extracellular matrix, biofilm formation is classified into either PIA-independent or PIA- ...
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Vaccines and Vaccine Candidates against Brucellosis
... B. abortus S19 is live smooth weakened vaccine used to control of bovine brucellosis. This strain was isolated in the early twentieth century and naturally attenuated when an infectious culture of B. abortus was ...
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