vaccine strategy
A Novel Non-Replication-Competent Cytomegalovirus Capsid Mutant Vaccine Strategy Is Effective in Reducing Congenital Infection
... a vaccine against congenital CMV has to induce both an antibody to key neutralizing glycoprotein complexes that are essential for virus entry and additionally target important T cell target antigens to provide a ...
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Vaccine strategy when the smallpox model fails: 1. immune cognition, Malaria and the Fulani
... of vaccine strategies where the smallpox model ...one-size-fits-all vaccine strategy. On the other hand, a more flexible vaccine strategy which makes appropriate use of ICC mechanisms ...
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Systemic Immunization with an ALVAC-HIV-1/Protein Boost Vaccine Strategy Protects Rhesus Macaques from CD4+ T-Cell Loss and Reduces both Systemic and Mucosal Simian-Human Immunodeficiency Virus SHIVKU2 RNA Levels
... poxvirus vaccine such as NYVAC-SIV results in generation of memory T cells present in mucosal sites as well as systemic sites (54), we sought to determine whether systemic immuni- zation of animals with the ...
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Epitope Based Vaccine Strategy against Sea Anemone Toxins through in Silico Route
... In this paper, minimization of predicted epitope and pinpointing the efficient epitope sequence is done to reveal greatest chance for eliciting cell-mediated immunity in human body against sea anemone toxins. Predicted ...
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Orthogonal inactivation of influenza and the creation of detergent resistant viral aggregates: towards a novel vaccine strategy
... These results, combined with similar results from another group [16], indicate that Triton can be used to successfully inactivate influenza virus. This is of impor- tant note when considering Triton (or potentially other ...
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A New Vaccine Strategy of Dendritic Cell Presented Kinetoplastid Membrane (KMP 11) as Immunogen for Control against Experimental Visceral Leishmaniasis
... There was ample evidence on the abilities of KMP-11 immunomodulation through DCs which clear Leishmania amastigotes in infected animals more ef- fectively than un-immunized groups. The above encouraging findings on im- ...
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Risk Factors Associated With Severe Influenza Infections in Childhood: Implication for Vaccine Strategy
... Conclusions. Considering that the majority of chil- dren hospitalized for influenza do not belong to the specific risk groups targeted by current recommenda- tions, and that one third are <6 months of age, the target ...
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Vaccine Efficacy of Inactivated, Chimeric Hemagglutinin H9/H5N2 Avian Influenza Virus and Its Suitability for the Marker Vaccine Strategy
... H9/H5N2 vaccine induced broad cross-reactive antibody responses that protected immunized hosts against homologous and heterologous lethal challenges with H5N8 and maH5N2 viruses ...H9/H5N2 vaccine groups ...
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Addressing vaccine hesitancy requires an ethically consistent health strategy
... address vaccine anxieties through exchanges between parents and HCPs run in tandem with approaches that coerce or ‘nudge’ parents to vaccinate their ...ing: vaccine mandates; the recent ‘No jab, no pay’ ...
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Malaria Policy Advisory Committee to the WHO: conclusions and recommendations of seventh biannual meeting (March 2015)
... elimination strategy; an update on the RTS,S vaccine; G6PD testing to support the safe use of anti-relapse therapy for Plasmodium vivax; update from the Vector Control Advisory Group; newly proposed ...
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Review Article Mucosal anti-caries DNA vaccine: a new approach to induce protective immunity against streptococcus mutans
... (P region) [18]. The adhesin known as PAc of cariogenic pathogen S. mutans is a target of protective immunity and candidate vaccine antigen [19, 20]. Antibodies could block the receptors necessary for colonization ...
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HERBS AS TRADITIONAL MEDICINES: A REVIEW
... bacterial vaccine is cultivation of the specific organism in a suitable broth ...Typhoid vaccine, cholera vaccine, plague vaccine, pertussis vaccine, BCG vaccine are the ...
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Optimal prophylactic vaccination in segregated populations : when can we improve on the equalising strategy?
... vaccination strategy, the equalising strategy and random vacci- nation, in terms of their effect on the household reproductive number, R ...equalising strategy does not hold for all levels of ...
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Alternative Strategy for a Quadrivalent Live Attenuated Influenza Virus Vaccine
... This strategy—referred to as IAV att—is safe and effective, resulting in protection against avian- and mammalian-origin influenza virus strains in a variety of avian and mammalian species (23, ...similar ...
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Novel Biopanning Strategy To Identify Epitopes Associated with Vaccine Protection
... applicable strategy to profile the antibody (Ab) repertoire of protected vaccine recipients, using recombinant phages encoding random peptide ...multicomponent vaccine (multimeric HIV-1 gp160, HIV-1 ...
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Generation of Plasmodium falciparum parasite inhibitory antibodies by immunization with recombinantly expressed CyRPA
... stage vaccine candidate ...This strategy has led to the identification of PfCyRPA as prom- ising blood-stage malaria vaccine candidate: generated anti-PfCyRPA mAbs showed parasite in vitro and in ...
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Preferential Targeting of Conserved Gag Regions after Vaccination with a Heterologous DNA Prime-Modified Vaccinia Virus Ankara Boost HIV-1 Vaccine Regimen
... H igh antigenic variability of common viruses causing either chronic (e.g., human immunodeficiency virus [HIV] and hepatitis C virus [HCV]) or acute (e.g., influenza virus and dengue virus) disease complicates the design ...
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A Prime-Boost Strategy Using the Novel Vaccine Candidate, LemA, Protects Hamsters against Leptospirosis
... promising strategy in the development of new vaccines against ...DNA-type vaccine candidates have been evaluated in several lep- tospirosis vaccine studies (23–25), including prime-boost strate- gies ...
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Haemophilus influenzae Vaccine
... Cochi SL, Broome CV, Hightower AW: Immunization of US Children with Hemophilus influenzae type b polysaccharide vaccine: A cost-effectiveness model of strategy assessment. JAMA 1985;253:[r] ...
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Hepatitis A Vaccine Recommendations
... A vaccine, the Centers for Disease Control and Prevention and the American Academy of Pediatrics have been implementing an incremental hepatitis A immunization strategy for ...A vaccine from 24 to 12 ...
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