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Vaso-occlusive crisis

Vaso-occlusive crisis in sickle cell disease: current paradigm on pain management

Vaso-occlusive crisis in sickle cell disease: current paradigm on pain management

... The pharmacologic options for pain management in sickle cell vaso-occlusive crisis are effective in both pediatric and adult patients. Non-opioids and opioids still form the main- stay of analgesic ...

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Prevention practices influencing frequency of occurrence of vaso-occlusive crisis among sickle cell patients in Abeokuta South Local Government Area of Ogun State, Nigeria

Prevention practices influencing frequency of occurrence of vaso-occlusive crisis among sickle cell patients in Abeokuta South Local Government Area of Ogun State, Nigeria

... of vaso-occlusive ...of vaso-occlusive crisis among sickle cell pa- tients [8–14] Further experimental studies will be needed to ascertain which of this is more essential in the ...

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Pattern of Serum Cytokine Expression and T-Cell Subsets in Sickle Cell Disease Patients in Vaso-Occlusive Crisis

Pattern of Serum Cytokine Expression and T-Cell Subsets in Sickle Cell Disease Patients in Vaso-Occlusive Crisis

... sickle vaso-occlusive crisis (VOC) in sickle cell disease (SCD) patients involves the accumulation of rigid sickle cells and the stimulation of an ongoing inflammatory response, as well as the stress ...

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Benefits of Simple Exchange Transfusion in Sickle Cell Disease (HbSS) with Vaso Occlusive Crisis Not Responding to Standard Therapy

Benefits of Simple Exchange Transfusion in Sickle Cell Disease (HbSS) with Vaso Occlusive Crisis Not Responding to Standard Therapy

... Sickle cell disease is an autosomal recessive genetic disease. Vaso occlusive crisis (VOC) is fre- quently seen in such patients. Painful VOC is usually recurrent, of variable severity due to many ...

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Primary Hyperparathyroidism Mimicking Vaso-occlusive Crises in Sickle Cell Disease

Primary Hyperparathyroidism Mimicking Vaso-occlusive Crises in Sickle Cell Disease

... pain crisis. The diagnosis of vaso-occlusive crisis should be considered as the diagnosis of exclusion and, importantly, should be revised in the presence of prolonged pain or unusual ...

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Plasma Homocysteine, Methyl-Malonic Acid, Vitamin B12

Plasma Homocysteine, Methyl-Malonic Acid, Vitamin B 12 and Folate Levels in Adult Nigerian Sickle Cell Anaemia Patients

... level found in vaso-occlusive crisis group was not significant when compared with the steady state group. This is difficult to explain but several therapeutic interventions like intake of routine ...

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Knowledge, Attitudes and Practices of Parents in the Vaso Occlusive Crises of the Sick Children in Brazzaville

Knowledge, Attitudes and Practices of Parents in the Vaso Occlusive Crises of the Sick Children in Brazzaville

... of vaso-occlusive crises, to identify their attitudes and ...the vaso-occlusive crisis 101 cases (31.7%). In a vaso-occlusive crisis, they used a health facility ...

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Study of Prognostic Factors of Death in Children with Sickle Cell Diseases Followed at the Albert Royer National Children's Hospital Center, Dakar, Senegal

Study of Prognostic Factors of Death in Children with Sickle Cell Diseases Followed at the Albert Royer National Children's Hospital Center, Dakar, Senegal

... of vaso- occlusive crisis (VOC) in the last year of follow-up duration of which is ≥72h, type of hemoglobinopathy, baseline hemoglobin level, fetal hemoglobin level at diagnosis, vaccination with at ...

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Pregnancy in Sickle Cell Disease is a Very High-Risk Situation: A Case Control Study

Pregnancy in Sickle Cell Disease is a Very High-Risk Situation: A Case Control Study

... Sickle cell hemoglobinopathy is a common disease in central India. pregnancy with sickle cell disease is bound to be associated with feto maternal complications. Vaso occlusive crisis, anamia, ...

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Prophylaxis oral aspartame improves anaemia and decreases frequency and severity of vaso-occlusive painful crisis among sickle cell disease patients and noninferior to hydroxyurea

Prophylaxis oral aspartame improves anaemia and decreases frequency and severity of vaso-occlusive painful crisis among sickle cell disease patients and noninferior to hydroxyurea

... and vaso-occlusive painful ...frequent vaso-occlusive crisis and/ or chronic anaemia after exclusion of phenylketonurea, vitamin B12, folic acid deficiency and recent blood transfusion ...

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Back pain: the sole of presentation of sickle cell disease

Back pain: the sole of presentation of sickle cell disease

... Abstract: Diagnosing back pain in children and adolescents can be a challenge to health care providers. Although studies show that more than half of the cases of back pain in children are of non-organic cause, missing ...

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Cytokine profiles in sickle cell anemia: Pathways to be unraveled

Cytokine profiles in sickle cell anemia: Pathways to be unraveled

... Sickle cell anemia (SCA) is a genetically inherited hemolytic disorder characterized by chronic inflam- mation. Cytokine expression affects the pivotal path- ways that contribute to disease pathogenesis, but the ...

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Pituitary injury and persistent hypofunction resulting from a peripartum non-hemorrhagic, vaso-occlusive event

Pituitary injury and persistent hypofunction resulting from a peripartum non-hemorrhagic, vaso-occlusive event

... Bromocriptine acts as a dopamine agonist, and its side effects, which are mostly minor, include orthostatic hypotension, nausea, and headaches. Although it is rare, vasospasm has been described as being related to the ...

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Hematological parameters in Ghanaian sickle cell disease patients

Hematological parameters in Ghanaian sickle cell disease patients

... The hematological profile of Ghanaian SCD patients has not been studied extensively in recent years. Findings from such work may provide a predictive data of SCD patients’ hematological parameters in Ghana as well as ...

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Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis

Low-dose methotrexate in sickle-cell disease: a pilot study with rationale borrowed from rheumatoid arthritis

... This was a prospective pilot study that enrolled young adult patients with sickle cell disease who were under chronic hydroxyurea treatment and had more than 3 severe VOC episodes/year, that were refractory to opioids ...

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Serum Biomarkers for Identifying Acute Chest Syndrome Among Patients Who Have Sickle Cell Disease and Present to the Emergency Department

Serum Biomarkers for Identifying Acute Chest Syndrome Among Patients Who Have Sickle Cell Disease and Present to the Emergency Department

... with vaso-occlusive crises or fever in which we compared levels of secretory phospholipase A2 (sPLA2), endothe- lin-1, interleukin-6 (IL-6), and peripheral white blood cell count (WBC) in cases that were ...

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Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease

Role of free radicals in the pathogenesis of acute chest syndrome in sickle cell disease

... Although it appears that vitamin E depletion may play a role in the development of vaso-occlusion, the effect of vitamin E supplementation is unclear. In two small prospective studies that evaluated the effect of ...

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Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes.

Interactions among methylenetetrahydrofolate reductase (MTHFR) and cystathionine β-synthase (CBS) polymorphisms - a cross-sectional study: multiple heterozygosis as a risk factor for higher homocysteine levels and vaso-occlusive episodes.

... of thrombosis were submitted to genotyping by PCR-based methods and serum dosages of folic acid, vitamin B12 and Hcy. Except for the CBS G919A polymorphism, all other genetic markers were in Hardy- Weinberg equilibrium. ...

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Can Endarterectomy Be Useful in Peripheral Arterial Occlusive Disease with Critical Limb Ischemia?

Can Endarterectomy Be Useful in Peripheral Arterial Occlusive Disease with Critical Limb Ischemia?

... In 1946 Portugese Surgeon Dos Santos did first TEA through 2 arterectomies and he called it as disobliteration [1]. Leriche termed removal of obstructing thrombus as well as diseased arterial intima as ...

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Multicentric Experience in Distal to Proximal Revascularization of Tandem Occlusion Stroke Related to Internal Carotid Artery Dissection

Multicentric Experience in Distal to Proximal Revascularization of Tandem Occlusion Stroke Related to Internal Carotid Artery Dissection

... placement. Cervical carotid artery stent placement was performed using the carotid Wallstent (Boston Scientific), Precise (Cordis, Fremont, California), Cristallo Ideale (Medtronic, Roncadelle, It- aly), or, in case of ...

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