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Viral production

Apoptosis of viral-infected airway epithelial cells limit viral production and is altered by corticosteroid exposure

Apoptosis of viral-infected airway epithelial cells limit viral production and is altered by corticosteroid exposure

... anti-apoptotic viral response will determine the clearance of viral- infected cells and persistence of ...to viral-induced airway ...in viral bronchiolitis and asthma. Reduced viral ...

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Reassessing the Human Immunodeficiency Virus Type 1 Life Cycle through Age-Structured Modeling: Life Span of Infected Cells, Viral Generation Time, and Basic Reproductive Number, R0

Reassessing the Human Immunodeficiency Virus Type 1 Life Cycle through Age-Structured Modeling: Life Span of Infected Cells, Viral Generation Time, and Basic Reproductive Number, R0

... age-dependent viral production rates and infected-cell death rates among HIV-1-infected ...age-dependent viral production rates and infected-cell death ...from viral load decay data, we ...

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Viral dynamics in two trophically different areas in the Central Adriatic Sea

Viral dynamics in two trophically different areas in the Central Adriatic Sea

... where viral decay only partially balanced viral production ...lower viral production, and higher production of bacteria at every investigated depth of the open-sea station in the ...

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The stimulatory effect of actinomycin D on avian reovirus replication in L cells suggests that translational competition dictates the fate of the infection.

The stimulatory effect of actinomycin D on avian reovirus replication in L cells suggests that translational competition dictates the fate of the infection.

... titative differences in homogeneous viral production by all the cells and that ActD inhibits host transcription without affecting viral mRNA synthesis 16, we propose a model for the inte[r] ...

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Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication

Mutation of Putative N-Glycosylation Sites on Dengue Virus NS4B Decreases RNA Replication

... in viral genome ...of viral production efficiency without affecting secretion or infectivity of the virion in mammalian and mosquito C6/36 ...the viral replication ...

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The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1

The Torsin Activator LULL1 Is Required for Efficient Growth of Herpes Simplex Virus 1

... reduces viral production only marginally, but that knockout of LULL1 reduces HSV-1 production by more than one order of ...on viral production. Surprisingly, the defect in viral ...

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Assessment of packed bed bioreactor systems in the production of viral vaccines

Assessment of packed bed bioreactor systems in the production of viral vaccines

... the production of vaccines so as to make them affordable for mass ...the production of some viral vaccines like Rabies, Hepatitis-A and Chikungunya vaccines in comparison to conventional systems like ...

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Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population

Genotypic and Phenotypic Diversity of Herpes Simplex Virus 2 within the Infected Neonatal Population

... (UL22), viral serine/threonine kinase US3, viral thymidine kinase (UL23), major capsid protein UL19, and DNA polymerase pro- cessivity factor ...specific viral genetic candidates under consideration, ...

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Formation of the Poliovirus Replication Complex Requires Coupled Viral Translation, Vesicle Production, and Viral RNA Synthesis

Formation of the Poliovirus Replication Complex Requires Coupled Viral Translation, Vesicle Production, and Viral RNA Synthesis

... (Table 1). This is visualized in Fig. 3B for cells transfected with 2BC. The percentage of cells expressing a membrane-binding protein varied between 20 and 90%, depending on the plasmid used for induction of membrane ...

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Intracellular Dynamics of HIV Infection

Intracellular Dynamics of HIV Infection

... EGFP production in an infected cell and then the sudden switch from no EGFP production to full production is likely an oversimplification of a true ...EGFP production may in part occur because ...

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Avian sarcoma virus-transformed quail clones defective in the production of focus-forming virus.

Avian sarcoma virus-transformed quail clones defective in the production of focus-forming virus.

... Five clones that failed to produce focus-forming virus were examined for i intactness of the integrated proviral DNA, ii intracellular viral RNA production, iii intracellular viral antig[r] ...

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Human Immunodeficiency Virus Type 1 N-Terminal Capsid Mutants That Exhibit Aberrant Core Morphology and Are Blocked in Initiation of Reverse Transcription in Infected Cells

Human Immunodeficiency Virus Type 1 N-Terminal Capsid Mutants That Exhibit Aberrant Core Morphology and Are Blocked in Initiation of Reverse Transcription in Infected Cells

... Here, we demonstrate that all three mutants produce essen- tially normal levels of virus particles but are unable to replicate in single-cycle and long-term culture assays. These particles also exhibit abnormal core ...

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Going against the Tide: Selective Cellular Protein Synthesis during Virally Induced Host Shutoff

Going against the Tide: Selective Cellular Protein Synthesis during Virally Induced Host Shutoff

... the viral replication requirement, a subset of cellular proteins may be selectively synthesized by production of more of the necessary nascent transcripts, by increasing their translation efficiency, or by ...

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Comparison of Type I Interferon Expression in Adult and Neonatal Mice during Respiratory Viral Infection

Comparison of Type I Interferon Expression in Adult and Neonatal Mice during Respiratory Viral Infection

... Mammalian interferons are classified into three types: Type I interferon, Type II interferon, and Type III interferon. Type I interferon includes the two major kinds IFN-α and IFN-β, as well as the less studied IFN-ε, ...

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Identification of viral determinants of macrophage tropism for simian immunodeficiency virus SIVmac.

Identification of viral determinants of macrophage tropism for simian immunodeficiency virus SIVmac.

... Virus production in rhesus macaque macrophage cultures infected with parental and recombinant viruses DISCUSSION Identification of the viral determinants of cell tropism is an important [r] ...

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Endoplasmic Reticulum Chaperones Are Involved in the Morphogenesis of Rotavirus Infectious Particles

Endoplasmic Reticulum Chaperones Are Involved in the Morphogenesis of Rotavirus Infectious Particles

... Rotaviruses, the leading cause of severe dehydrating diar- rhea in infants and young children worldwide, are nonenvel- oped viruses formed by three concentric layers of protein that enclose a double-stranded RNA genome. ...

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A Narcissus mosaic viral vector system for protein expression and flavonoid production

A Narcissus mosaic viral vector system for protein expression and flavonoid production

... basal production of the flavonols kaempferol-3-O-rutinoside and quercetin- 3-O-rutinoside, which are from branches off the flavo- noid pathway prior to ...anthocyanin production, PAP1 and PAP1-GFP ...

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Exploration of Panviral Proteome: High-Throughput Cloning and Functional Implications in Virus-host Interactions

Exploration of Panviral Proteome: High-Throughput Cloning and Functional Implications in Virus-host Interactions

... Rubella virus has a small genome composed of single stranded (ss+) RNA that produces only five proteins (E1, E2, capsid, P90 and P150). To demon- strate the use of our panviral proteome collection in the study of ...

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Viral determinants of rotavirus pathogenicity in pigs: production of reassortants by asynchronous coinfection.

Viral determinants of rotavirus pathogenicity in pigs: production of reassortants by asynchronous coinfection.

... ture-sensitive mutants. His findings suggested that genetic in- teractions are not entirely excluded at asynchronous infections; highest reassortment efficiency, however, has been achieved at synchronous infections, ...

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Production of Recombinant Snakehead Rhabdovirus: the NV Protein Is Not Required for Viral Replication

Production of Recombinant Snakehead Rhabdovirus: the NV Protein Is Not Required for Viral Replication

... A defining feature of all viruses belonging to the genus Novirhabdovirus is a small gene located between the viral gly- coprotein (G) and polymerase (L) genes. The gene is always approximately 500 nucleotides long ...

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