Viral rna
Nucleocapsid-Independent Specific Viral RNA Packaging via Viral Envelope Protein and Viral RNA Signal
... non-MHV RNA transcript in the absence of N ...enveloped RNA viruses studied thus far, N protein or capsid protein plays an essential role in viral RNA ...MHV RNA packaging is ...non-MHV ...
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Constraints of Viral RNA Synthesis on Codon Usage of Negative-Strand RNA Virus
... in viral RNA synthesis were not related to protein translation since all viral proteins were produced by other ...the viral genome in the nucleocapsid plays an essential role in regulating ...
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Interaction of the Influenza A Virus Nucleocapsid Protein with the Viral RNA Polymerase Potentiates Unprimed Viral RNA Replication
... in viral RNA replication, in the absence of a ...purified viral polymerase to enable its 3 ⬘ end to bind to the PB1 subunit of the polymerase ...any RNA at 24-nt intervals from one end to the ...
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Gel Electrophoresis of Avian Leukosis and Sarcoma Viral RNA in Formamide: Comparison with Other Viral and Cellular RNA Species
... Gel Electrophoresis of Avian Leukosis and Sarcoma Viral RNA in Formamide: Comparison with Other Viral and Cellular RNA Species Received for publication 25 April 1973 Class a and class b [r] ...
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Different De Novo Initiation Strategies Are Used by Influenza Virus RNA Polymerase on Its cRNA and Viral RNA Promoters during Viral RNA Replication
... single-stranded RNA viruses to initiate and control their replication via the synthesis of replicative ...virus RNA polymerase and establish whether initiation of cRNA and viral RNA (vRNA) ...
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Suppression of Viral RNA Recombination by a Host Exoribonuclease
... of RNA recombination in Tomato bushy stunt virus ...-truncated viral RNAs in xrn1 ⌬ mutant strains but not in the parental yeast strains, suggesting that these RNAs might serve as recombination substrates ...
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Metabolism of viral RNA in murine leukemia virus-infected cells; evidence for differential stability of viral message and virion precursor RNA.
... 3 Metabolism of Viral RNA in Murine Leukemia Virus-Infected Cells: Evidence for Differential Stability of Viral Message and Virion Precursor RNA Received 29 April 1981/Accepted 28 July 1[r] ...
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Sequences at the 3′ Untranslated Region of Bamboo Mosaic Potexvirus RNA Interact with the Viral RNA-Dependent RNA Polymerase
... genomic RNA was found to fold into a series of stem-loop structures including a pseudoknot ...for viral RNA replication and were believed to be recognized by the replicase ...coli-expressed ...
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A Recombinant Hepatitis C Virus RNA-Dependent RNA Polymerase Capable of Copying the Full-Length Viral RNA
... recombinant RNA-dependent RNA polymerases (RdRp), the NS5B enzymes, of hepatitis C virus (HCV) could function only in a primer-dependent and template-nonspecific manner, which is different from the expected ...
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Structure-Function Relationships Underlying the Replication Fidelity of Viral RNA-Dependent RNA Polymerases
... Viral RNA-dependent RNA polymerases are considered to be low-fidelity enzymes, providing high mutation rates that allow for the rapid adaptation of RNA viruses to different host cell ...
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Stability of a Long Noncoding Viral RNA Depends on a 9-nt Core Element at the RNA 5' End to Interact with Viral ORF57 and Cellular PABPC1
... of viral lytic gene ...of viral lytic genes [11,12] and ORF57 (Mta, mRNA transcript ac- cumulation), a multifunctional protein that promotes the accumulation of viral intron-less transcripts [13-17] ...
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Norovirus RNA Synthesis Is Modulated by an Interaction between the Viral RNA-Dependent RNA Polymerase and the Major Capsid Protein, VP1
... for RNA synthesis by the RNA-dependent RNA polymerase (RdRp) of noroviruses, we previously ob- served that VP1, the major structural protein of the human ...unrelated RNA viruses ...the ...
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Encapsidation of Viral RNA in Picornavirales: Studies on Cowpea Mosaic Virus Demonstrate Dependence on Viral Replication
... the RNA molecules produced by replication and those produced by transcription is the location of their synthesis (cytoplasm versus ...replicated RNA molecules and newly translated coat protein molecules in ...
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Role of RNase MRP in Viral RNA Degradation and RNA Recombination
... Many RNA viruses evolve rapidly due to a high frequency of mutations and genetic recombination as well as reassortment of genomic components (1, ...of viral RNA genomes has revealed that ...
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Peanut Clump Virus RNA-1-Encoded P15 Regulates Viral RNA Accumulation but Is Not Abundant at Viral RNA Replication Sites
... in viral replication but is only very transiently present at the viral RNA replication sites and is hence difficult to detect ...on viral RNA replication and/or accumulation is ...the ...
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Molecular Bases of Viral RNA Targeting by Viral Small Interfering RNA-Programmed RISC
... was identified as the 5 ⬘ cleavage product of GFP-Cym( ⫹ ) sensor mRNA (see later). The level of GFP- PoLV( ⫹ ) mRNA remained intact and accumulated at a sig- nificantly higher level than the GFP-Cym( ⫹ ) mRNA, indicat- ...
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Armored RNA Technology for Production of Ribonuclease Resistant Viral RNA Controls and Standards
... lambda RNA sequences of ...the RNA was isolated from each of these con- ...lambda RNA contained a reRNA of the expected size, as determined by ethidium bromide ...contained RNA which was ...
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Gliotoxin: inhibitor of poliovirus RNA synthesis that blocks the viral RNA polymerase 3Dpol.
... Therefore, two agents that block two different poliovirus proteins involved in RNA replication are now available: a compound that interferes with the activity of poliovirus protein 2C, g[r] ...
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Identification of a Natural Viral RNA Motif That Optimizes Sensing of Viral RNA by RIG I
... Identification of a candidate motif essential for type I IFN induction by positive-sense DVG RNA. We have reported that alterations in the internal (noncomplementary) region of DVG- 546 drastically affect its ...
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Terminal Nucleotidyl Transferase Activity of RecombinantFlaviviridae RNA-Dependent RNA Polymerases: Implication for Viral RNA Synthesis
... Two additional HCV RdRps were generated to eliminate the possibility that an E. coli protein(s) responsible for TNTase activity copurified with H⌬21 but not m⌬21. First, a version lacking the C-terminal 51 amino acids, ...
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