viral transcription
Brd4 Activates Early Viral Transcription upon Human Papillomavirus 18 Infection of Primary Keratinocytes
... The viral genome is maintained as a low-copy-number, extrachro- mosomal element in these proliferating cells but switches to the late stage of the life cycle in differentiated ...the viral life cycle. In ...
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Rotavirus Glycoprotein NSP4 Is a Modulator of Viral Transcription in the Infected Cell
... of viral plus-strand ...in viral inclusion bodies (viroplasms). The viral endoplasmic reticulum (ER)-resident glycoprotein NSP4 recruits progeny DLPs formed in viroplasms to the ER, where the ...
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The Complementary Strand of the Human T-Cell Leukemia Virus Type 1 RNA Genome Encodes a bZIP Transcription Factor That Down-Regulates Viral Transcription
... the viral Tax protein to enhance the transcription of the HTLV-1 promoter (9, ...second viral protein that had never been characterized until ...novel viral protein is encoded by the ...
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HDAC inhibitors stimulate viral transcription by multiple mechanisms
... late transcription, it is also possible that the stimulation of transcription occurred at least in part as a result of the presence of more RNAPII transcription complexes on each of the transcrib- ...
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Interactions between coronavirus nucleocapsid protein and viral RNAs: implications for viral transcription.
... Lanes: A and F, controls showing the virus-specific RNA extracted from infected cells; D, all seven virus-specified RNAs immunoprecipitated by the anti-N monoclonal antibody; B, C, and E[r] ...
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Hsp70 Protein Positively Regulates Rabies Virus Infection
... the viral life cycle: genome replication, viral protein synthesis, viral assembly, and counterde- fense against cell apoptosis and innate ...During viral infection, large amounts of ...
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Morphological, Biochemical, and Functional Study of Viral Replication Compartments Isolated from Adenovirus-Infected Cells
... these viral sites in a dynamic spatiotemporal ...where viral DNA replication and gene expression take place (39, 41, 43, 75, 77, 78, 102, 103); hence, the localization of nucleolin at the periphery of RC ...
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The Vaccinia Virus A18R DNA Helicase Is a Postreplicative Negative Transcription Elongation Factor
... readthrough transcription on the viral ...readthrough transcription from converging promoters causes an accumulation of dsRNA, which triggers the 2-5A pathway, which in turn activates RNase L and ...
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A Herpesviral Immediate Early Protein Promotes Transcription Elongation of Viral Transcripts
... how transcription elongation occurs in infected cells with altered Pol II CTD ...decreased transcription during HSV-1 infection ...efficient viral transcription (24, 25, 31, ...cellular ...
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Expression and reactivation of HIV in a chemokine induced model of HIV latency in primary resting CD4+ T cells
... virus transcription via enhanced production of NF-kB [37-39] while phosphorylated STAT5 has been shown to bind and transactivate viral transcription in ex vivo primary CD4+ T-cells; in the HeLa cell ...
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Epstein-Barr virus infection in carcinoma of the salivary gland.
... Analyses of viral transcription in NPC specimens obtained at biopsy or passaged in nude mice have determined that the EBER RNAs, LMP mRNA, and transcription from the BamHI A fragment are[r] ...
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Detailed phenotypic characterization of five temperature-sensitive mutants in the 22- and 147-kilodalton subunits of vaccinia virus DNA-dependent RNA polymerase.
... Thus, when a cell is infected with an RNA polymerase mutant, early viral transcription proceeds from a virion-associated transcription complex which was assembled during growth of the vi[r] ...
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Regulation of the herpesvirus saimiri oncogene stpC, similar to that of T-cell activation genes, in growth-transformed human T lymphocytes.
... demonstrate transcription from the stpC/ tip gene complex in a regulated ...induced transcription engaged start sites differen- tially ...induced transcription presumably utilizes two pairs of CAAT ...
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Characterization of a Rous sarcoma virus mutant defective in packaging its own genomic RNA: biochemical properties of mutant TK15 and mutant-induced transformants.
... To see whether the deficiency of the viral genomic RNA in TK15 particles reflects any abnormality at the level of transcription of viral RNAs in infected cells, we examined the virus-spe[r] ...
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The stimulatory effect of actinomycin D on avian reovirus replication in L cells suggests that translational competition dictates the fate of the infection.
... titative differences in homogeneous viral production by all the cells and that ActD inhibits host transcription without affecting viral mRNA synthesis 16, we propose a model for the inte[r] ...
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DNA Virus Replication Compartments
... by viral and cellular ...the viral genome and viral and cellular proteins ...direct viral genome replica- tion and ...where viral ge- nomes are replicated and assembled has been ...
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The Late Promoter of the Human Cytomegalovirus Viral DNA Polymerase Processivity Factor Has an Impact on Delayed Early and Late Viral Gene Products but Not on Viral DNA Synthesis
... of transcription of the UL75 ORF is opposite to that of the UL76, -77, and -78 ...late viral gene ...on viral delayed early and late gene transcrip- ...
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Pre-mRNA Processing Factor Prp18 Is a Stimulatory Factor of Influenza Virus RNA Synthesis and Possesses Nucleoprotein Chaperone Activity
... in viral protein synthesis and/or viral RNA ...and viral mRNA in infected cells by quantitative reverse transcription-PCR ...of viral pre-mRNAs and therefore on viral RNA ...
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Herpesviruses and Chromosomal Integration
... of viral DNA in the hair follicles of CIHHV-6 pa- tients ( ⱖ 1 copy/hair follicle) (101), and the fact that high loads of viral DNA can be found in several tissues throughout the bodies of subjects with ...
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Transcription of True Late (γ2) Cytomegalovirus Genes Requires UL92 Function That Is Conserved among Beta- and Gammaherpesviruses
... within viral replication ...Although viral DNA is made at normal levels, viral capsid accumulation in the nucleus is severely compromised in UL92 mutant virus-infected cells, and mature virions are ...
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