Visceral Leishmaniasis
Epidemiology of visceral leishmaniasis
... of leishmaniasis, a neglected tropical ...human visceral leishmaniasis (VL), which leads to substantial health problems or death for up to 400,000 people per ...
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The Dog as a Risk Factor in Transmission of Visceral Leishmaniasis: A Review
... Visceral leishmaniasis (VL) is a serious public health problem in Brazil and worldwide. Despite the euthanasia of dogs serologically positive, such action has not solved the endemic in Brazil. A risk area ...
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Antigen specific immunosuppression in visceral leishmaniasis is cell mediated
... mononuclear cell (MNC) populations and in co-cultivation experiments. Adherent cells were depleted on plastic and by passage on nylon wool columns. High-avidity Fc+ cells were depleted by adherence to BSA-anti-BSA ...
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Multicomponent Chimeric Antigen for Serodiagnosis of Canine Visceral Leishmaniasis
... In this work, we describe the assembly of a synthetic gene coding for several antigenic determinants found in different Leishmania infantum antigens. Selected epitopes were derived from the ribosomal proteins LiP2a, ...
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Transmission, reservoir hosts and control of zoonotic visceral leishmaniasis
... Zoonotic visceral leishmaniasis (ZVL) caused by Leishmania infantum is an important disease of humans and dogs. Here we review aspects of the transmission and control of ZVL. Whilst there is clear evidence ...
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Immunomodulatory therapy of visceral leishmaniasis in HIV coinfected patients
... with visceral leishmaniasis (VL)–human immunodeiciency virus (HIV) coinfection experience increased drug toxicity and treatment failure rates compared to VL patients, with more frequent VL relapse and ...
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Revisiting area risk classification of visceral leishmaniasis in Brazil
... Background: Visceral leishmaniasis (VL) is a neglected tropical disease of public health relevance in Brazil. To prioritize disease control measures, the Secretaria de Vigilância em Saúde of Brazil ’ s ...
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Disorganization of spleen compartments and dermatitis in canine visceral leishmaniasis
... Canine visceral leishmaniasis (CVL) is a re-emergent zoonotic disease caused by Leishmania infantum that is largely found in tropical and subtropical countries (Ste- verding ...
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Comorbid infections induce progression of visceral leishmaniasis
... Vector borne zoonotic diseases remain important public health concerns across the globe. No infection occurs in isolation, instead comorbid infection(s) can alter the in- flammatory state and subsequently disease outcome ...
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Visceral leishmaniasis in 26 HIV negative adults
... We collected 26 cases of visceral leishmaniasis diag- nosed in HIV-negative adults. Patients ranged in age from 15 to 65 years, with mean ages of 28 years. There were 15 men and 11 women. All patients were ...
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Tissue Cytokine Responses in Canine Visceral Leishmaniasis
... To elucidate the local tissue cytokine response of dogs infected with Leishmania chagasi, cytokine mRNA levels were measured in bone marrow aspirates from 27 naturally infected dogs from Brazil and were compared with ...
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Quantification of the natural history of visceral leishmaniasis and consequences for control
... Visceral leishmaniasis (VL) in the Indian sub-continent (ISC) is a disease caused by chronic infection with the protozoan parasite Leishmania donovani, transmitted by the Phlebotomus argentipes ...manifest ...
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Interest in paromomycin for the treatment of visceral leishmaniasis (kala-azar)
... Abstract: Leishmaniasis is an important vector-borne disease, and it is classified as one of the most important tropical fly-borne ...and visceral forms. Visceral leishmaniasis, which is also ...
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Visceral Leishmaniasis with Endobronchial Involvement in an Immunocompetent Adult
... of visceral leishmaniasis in an immuno- competent adult who presented with cough and hemop- tysis along with the typical clinical features of the dis- ...
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An Overview of theLaboratory Diagnostic Procedures of Visceral Leishmaniasis (Kala-Azar)
... Visceral leishmaniasis (Kala-azar) is a systemic infection disease that can be diagnosed by some invasive procedures such as splenic, liver biopsy or bone marrow aspiration, whichare determined as the gold ...
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Anti-Leishmania infantum IgG Antibody Avidity in Visceral Leishmaniasis
... IgG avidity tests are used to discriminate acute from chronic infections. There are few reports on the IgG avidity profile of pa- tients with visceral leishmaniasis (VL). This study investigated the ...
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KSAC, the First Defined Polyprotein Vaccine Candidate for Visceral Leishmaniasis
... canine visceral leishmaniasis, and against ...cost-effective leishmaniasis vaccine capable of protecting both humans and dogs against multiple Leishmania ...
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Skin parasite landscape determines host infectiousness in visceral leishmaniasis
... Increasing evidence suggests that the infectiousness of patients for the sand fl y vector of visceral leishmaniasis is linked to parasites found in the skin. Using a murine model that supports extensive skin ...
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Application of Recombinant Proteins for Serodiagnosis of Visceral Leishmaniasis in Humans and Dogs
... Visceral leishmaniasis (VL) is a zoonotic disease caused by leishmania species. Dogs are considered to be the main reservoir of VL. A number of methods and antigen-based assays are used for the diagnosis of ...
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Immunodiagnosis of Visceral Leishmaniasis: Current Status and Challenges: A Review Article
... “visceral leishmaniasis”, or “kala-azar” subsequently combined with the search terms “diagnosis”, “serodiagnosis”, “human”, “sero- logical”, “antigen detection” or "antibody de- ...
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