Wallerian degeneration
Diffusion Weighted Imaging of Acute Corticospinal Tract Injury Preceding Wallerian Degeneration in the Maturing Human Brain
... between Wallerian degen- eration, as detected with T2-weighted MR imaging, and long-term morbidity ...of Wallerian degeneration in neonates and infants by using T2-weighted imaging is complicated by ...
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Wallerian degeneration: gaining perspective on inflammatory events after peripheral nerve injury
... axon degeneration in Wallerian degenera- tion comes from studies involving the slow Wallerian degeneration (Wld S ) mouse (reviewed by ...axon degeneration defines when subsequent, more ...
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Deletion of SIRPα (signal regulatory protein-α) promotes phagocytic clearance of myelin debris in Wallerian degeneration, axon regeneration, and recovery from nerve injury
... the Wallerian degenerating nerve segment located distal to and beyond the lesion site, determined by the nature of Wallerian ...in Wallerian degeneration, which leads residual myelin debris to ...
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Relationship of acute axonal damage, Wallerian degeneration, and clinical disability in multiple sclerosis
... of Wallerian degeneration in patients with short- and long-standing disease harboring early- and late-stage ...ing Wallerian degeneration helps to decrease inflamma- tory axonal damage in a ...
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An assessment of the correlation between early postinfarction pyramidal tract Wallerian degeneration and nerve function recovery using diffusion tensor imaging.
... Pyramidal tract Wallerian degeneration (WD) was first discovered by Waller et al. in the brain tissue of patients with brain injury (Waller, 1850). It refers to the anterograde degenerative process of the ...
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NMN deamidase delays Wallerian degeneration and rescues axonal defects caused by NMNAT2 deficiency in vivo
... However, a recent study has questioned this model, reporting situations where genetic and pharmacological manipulation of the NAD biosynthetic pathway in primary DRG cultures raises NMN either in uninjured neurites that ...
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Wallerian degeneration of zebrafish trigeminal axons in the skin is required for regeneration and developmental pruning
... of Wallerian degeneration ...axon degeneration, a common mechanism for refining neuronal structure, several previously examined instances of developmental pruning were unaffected by WD ...the ...
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Wallerian degeneration: the innate-immune response to traumatic nerve injury
... normal Wallerian degeneration following cut ...lerian degeneration, but is expressed in injured Wld s PNS nerves at lesion sites where macrophages accumulate and phagocytose degenerated ...normal ...
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Design of a novel quantitative PCR (QPCR)-based protocol for genotyping mice carrying the neuroprotective Wallerian degeneration slow (Wlds) gene
... 16. Wishart TM, Paterson JM, Short DM, Meredith S, Robertson KA, Sutherland C, Cousin MA, Dutia MB, Gillingwater TH: Differential proteomic analysis of synaptic proteins identifies potential cellular targets and protein ...
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MR pathologic comparisons of wallerian degeneration in spinal cord injury
... of wallerian degeneration that occurs above and below a spinal cord injury, and to compare the MR findings with postmortem ...early wallerian degeneration in only the dorsal columns at 8 days ...
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Wallerian Degeneration in the Corticospinal Tract Evaluated by Diffusion Tensor Imaging Correlates with Motor Deficit 30 Days after Middle Cerebral Artery Ischemic Stroke
... ABBREVIATIONS: ANOVA ⫽ one-way analysis of variance; CST ⫽ corticospinal tract; DTI ⫽ diffu- sion tensor imaging; DWI ⫽ diffusion-weighted imaging; EPI ⫽ echo-planar imaging; FA ⫽ frac- tional anisotropy; FLAIR ⫽ ...
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Original Article TAK-242 affects Wallerian degeneration and peripheral nerve regeneration by regulating innate immunity in rats
... Abstract: Objective: The aim of this study is to distinguish whether Toll-like receptor 4 (TLR4) signaling is included in Wallerian degeneration (WD) and nerve regeneration or not after peripheral nerve ...
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Wallerian degeneration and inflammation in rat peripheral nerve detected by in vivo MR imaging
... Crush injury, neurotomy, and nerve grafting all resulted in high signal intensity along the course of the nerve observed on long TR/TE sequences, corresponding to edema and myelin breakd[r] ...
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Dyke Award paper MR of wallerian degeneration in the feline visual system: characterization by magnetization transfer rate with histopathologic correlation
... RESULTS: Within the first 2 weeks there is a statistically significant increase in magnetization transfer ratio relative to the control hemisphere within the white matter connections bet[r] ...
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Wallerian Degeneration in the Rat
... The observation that the concentrations of both nucleic acid and phospholipid in the sciatic nerve of the rat are negatively correlated with the wet weight of the nerve is in agreement w[r] ...
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The Outwandering of Cells in Tissue Cultures of Nerves Undergoing Wallerian Degeneration
... In the early stages of degeneration 2-4 days, the mean activity of the traumatic region explants is very much higher 4-20 times than that of the corresponding standard region.. With furt[r] ...
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Clinical Use of Diffusion Tensor Imaging for Diseases Causing Neuronal and Axonal Damage
... early wallerian degeneration, the right ipsi- lateral CST had a lower diffusion than the contralateral side, but the change in D av (4% increase) was minimal (Fig ...
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Neurobehavioural and brain histological effects in suckling pups of nursing rat dams orally dosed with mercuric acetate during pregnancy and lactation period
... the wallerian degeneration of the axon was associated with central chromatolysis which characterized by rounded pale swelling of purkinje cells, eccentric nuclei and dispersed Nissl substances (Figure 3), ...
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Poststroke Cerebral Peduncular Atrophy Correlates with a Measure of Corticospinal Tract Injury in the Cerebral Hemisphere
... Months are required before the associated wallerian degener- ation after cerebral infarction effects appreciable volume loss. Within a sample of hemiparetic chronic stroke patients, we found that a simple measure ...
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Mitochondrial impairment activates the Wallerian pathway through depletion of NMNAT2 leading to SARM1-dependent axon degeneration
... axon degeneration after CCCP ...axon degeneration. As with axon degeneration after axotomy (Di Stefano et ...neurite degeneration following CCCP ...axon degeneration (Sasaki et ...the ...
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