water in-soluble/ soluble drugs
NOVEL PHARMACEUTICAL APPLICATION OF MIXED SOLVENCY IN THE FORMULATION DEVELOPMENT OF SYRUPS (LIQUID ORAL SOLUTIONS) OF POORLY WATER-SOLUBLE DRUGS
... poorly water-soluble ...poorly water-soluble drugs can be improved by using “Mixed-solvency ...poorly water-soluble drugs based on these mixed-solvency phenomena ...
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Nanosuspension: An emerging trend to improve solubility of poorly water soluble drugs
... of drugs, but solubility plays an important role for drug ...discovered drugs are poorly water soluble. The poor water solubility of drugs always create major problem during drug ...
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SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUGS BY SOLID DISPERSION
... poorly water-soluble drugs are not suitable for improving their solubility by salt ...and water resulting in precipitation of poorly water-soluble drug, epigastric distress due ...
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CYCLODEXTRIN INCLUSION COMPLEX TO ENHANCE SOLUBILITY OF POORLY WATER SOLUBLE DRUGS: A REVIEW
... poorly water soluble ...poorly soluble drugs and hence to resolve the many issues associated with developing and commercializing poorly water soluble ...
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SOLUBILITY ENHANCEMENT OF POORLY WATER SOLUBLE DRUGS: A REVIEW
... Solubility can be also enhanced by alteration in molecular level of physical form of drug 4 . Solid dispersions are the most attractive method for improving of bioavailability of poorly water soluble ...
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SOLUBILITY ENHANCEMENT OF POOR WATER SOLUBLE DRUGS BY SOLID DISPERSION: A REVIEW
... poorly water soluble drugs remains one of the most challenging aspects of drug ...of drugs, which can subsequently affect the in vivo absorption of ...many drugs the bioavailability of ...
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CONTROLLED DRUG RELEASE FOR POORLY WATER SOLUBLE DRUGS A ROLE OF POLYMERIC NANOPARTICLES
... poorly water soluble drugs that account for approximately 25% of conventional, commercially available therapeutics and nearly 50%of candidates identified through screening techniques 56-57 ...
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SOLID DISPERSION- STRATEGY TO ENHANCE SOLUBILITY AND DISSOLUTION OF POORLY WATER SOLUBLE DRUGS
... of drugs those given as solid dosage forms remains a challenge for the formulation scientists due to solubility ...maximum drugs are poorly water soluble in pharmaceutical ...poorly ...
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A Review on Nanohybrids: Technique for Solubility Enhancement of Poorly Water Soluble Drugs
... that water solubility also requires the specification of temperature and pH; under certain physiological conditions many important drugs only show aqueous solubility, and reach to the site of ...
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Polymeric precipitation Inhibitors to improve the dissolution and absorption of poorly water soluble drugs
... basic drugs such as ketoconazole, dipyridamole, and carvedilol, easily dissolve in gastric pH and then may occur the precipitation or reach the supersaturation entering the duodenum due to higher environmental ...
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DEVELOPMENT OF DISINTEGRATION CONTROL MATRIX TABLETS OF FEBUXOSTAT
... Disintegration control matrix tablet (DCMT) is a new approach for poorly water soluble drugs which successfully sustain therelease up to 24hrs by controlling the disintegration rate of tablet. DCMT ...
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“Development and Evaluation of Asymmetric Membrane Capsules of Indomethacin: New Prospect in Osmotic Drug Delivery” by Rajwinder Kaur, Arun Gupta, Rupinder Kaur, Jasmine Kaur Bhatia, India.
... Significant change milestone in the oral NDDS is the development of the osmotic drug delivery system (ODDS), an innovative and highly versatile drug delivery system. ODDS are most promising strategy based systems for ...
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“NANOSUSPENSION - A NEW APPROACH OF BIOAVAILABILITY ENHANCEMENT” by Kalpesh S. Wagh*, Satish K. Patil, , Anup K. Akarte, Dheeraj T. Baviskar, India.
... poorly soluble drugs with soluble polymers and copolymers after dispersing in a liquid media has been ...poorly water soluble drugs; griseofulvin glibenclamide and nifedipine ...
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Effect of biocompatible polymers on the physicochemical properties of fenofibrate in nanoparticle system
... poorly water-soluble drugs in nanoparticle ...poorly water soluble fenofibrate were prepared using solvent evaporation technique with different biocompatible polymers such as ...
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Sustain-Release of Various Drugs from Leucaena Leucocephala Polysaccharide
... both water-soluble (acetaminophen, caffeine, theophylline and salicylic acid) and water-insoluble (indomethacin) drugs from Leucaena leucocephala seed Gum isolated from Leucaena leucocephala ...
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PREPARATION AND CHARACTERIZATION OF CHITOSAN NANOPARTICLES OF INSULIN FOR NASAL DELIVERY
... is the Higuchi dissolution constant. Higuchi model describes drug release as a diffusion process based in the Fick’s law, square root time dependent. This relation can be used to describe the drug dissolution from ...
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Volume 2 | Issue 1 - 2012
... interaction rather than changes in the bulk solvent properties as in other solublizing system such as co solvents, emulsion and pH adjustments. The dissociation is very rapid, quantitative and therefore predictable. ...
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A review on bio-availability enhancement techniques of poorly soluble drug
... in water by the addition of organic salts or also non- electrolytes, which must be physiologically compatible for pharmaceutical ...poorly water-soluble ...the water clusters. This makes the ...
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DELIVERY OF WATER-INSOLUBLE DRUGS: CAFFEINE MONOHYDRATE AND SALICYLIC ACID AS MICROCAPSULES USING IRVINGIA GUM AS THE COACERVATING AGENT
... The potential of irvingia gum as a coacervating agent was investigated in the microencapsulation of caffeine and salicylic acid. Irvingia gum was produced according to the methods described by previous workers. ...
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Chemical Modification: A unique solutions to Solubility problem
... poorly water soluble drugs. Badly water soluble drugs have solubility and dissolution related bioavailability ...administered drugs obtained completely absorb only when ...
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