whole brain radiotherapy
Whole brain radiotherapy with radiosensitizer for brain metastases
... avoiding unnecessary treatments [3-11]. Radiosensitizers are chemical or pharmacologic agents that increase the lethal effects of radiation if administered with it. In an attempt to improve outcomes, studies have ...
11
Phase II study of whole brain radiotherapy with or without erlotinib in patients with multiple brain metastases from lung adenocarcinoma
... of whole brain radiotherapy (WBRT) versus WBRT concurrent with erlotinib in patients with multiple brain metastases of lung ...of radiotherapy and continuing for 1 month following the ...
8
<p>Upfront whole brain radiotherapy for multiple brain metastases in patients with EGFR-mutant lung adenocarcinoma</p>
... Cranial radiotherapy plays a critical role in patients with BM from NSCLC, and whole brain radiotherapy (WBRT) is a primary treatment modality for patients with multiple brain ...of ...
11
Effect of Whole-Brain Radiotherapy in Alleviating Symptoms and Improving Quality of life in Patients with Brain Metastases – A Prospective Study
... proven brain metastasis who satisfied the inclusion criteria were given whole brain radiotherapy with a dose of 30 Gy in 10 fractions over 2 weeks with Cobalt-60 ...
10
Original Article Whether applying whole brain radiotherapy in stereotactic radiotherapy benefits for patients with brain metastases in Chinese population: evidence from meta-analysis
... with brain metastasis in Chinese population treated with stereotactic radiotherapy (SRT) plus whole-brain radiotherapy (WBRT) boost (hereafter denoted as SRT+WBRT) versus SRT ...with ...
8
Whole brain radiotherapy (WBRT) after local treatment of brain metastases in melanoma patients: Statistical Analysis Plan
... ulated radiotherapy (IMRT) for patients with brain me- tastasis, randomisation could occur before local radiotherapy treatment to allow for the use of simultan- eous integrated boost during WBRT (see ...
13
Combined action of EGFR tyrosine kinase inhibitors and whole-brain radiotherapy on <em>EGFR</em>-mutated non-small-cell lung cancer patients with brain metastasis
... that the addition of WBRT might increase the concentration of TKIs in the patients with BM. However, WBRT may induce neurotoxicity and lead to leukodystrophy. Thus, SRS or routine surgery could be used to remove a single ...
9
A pilot study using dynamic contrast enhanced-MRI as a response biomarker of the radioprotective effect of memantine in patients receiving whole brain radiotherapy
... All regions of interests (ROI) (tumor, NAWM, sagittal sinus) were manually segmented on the post- contrast MPRAGE by PW. The area of tumor was defined as the contrast enhancing volumes (using the pre and post-injection ...
11
Complete intracranial response to talimogene laherparepvec (T-Vec), pembrolizumab and whole brain radiotherapy in a patient with melanoma brain metastases refractory to dual checkpoint-inhibition
... melanoma brain metastasis are ...symptomatic brain metastasis ...asymptomatic brain lesions treated with either ipilimumab/nivolumab for four doses followed by nivolumab biweekly (cohort A) or ...
8
Palliative whole-brain radiotherapy and health-related quality of life for patients with brain metastasis in cancer
... drugs can infiltrate the brain tissue, while radiation destroys the blood–brain barrier. Several clinical trials have showed that WBRT combined with CT is not only more effective than WBRT alone but also ...
6
<p>Survival and intracranial control outcomes of whole-brain radiotherapy (WBRT) alone versus WBRT plus a radiotherapy boost in non-small-cell lung cancer with brain metastases: a single-institution retrospective analysis</p>
... their brain radiotherapy method: one group was treated with WBRT alone (WBRT-alone group) and another group was treated with WBRT plus RTB (WBRT plus RTB ...
18
Neurocognition of patients on whole brain radiotherapy: A prospective study
... The overall neurocognitive scores deteriorated over time. The study compared neurocognitive function against survival of the patients. They found that impairment in memory (HVLT recognition, recall, and delayed recall), ...
144
Original Article Endostatin improve the effect of radiotherapy in human NSCLC patients with brain metastases
... adays whole brain radiotherapy (WBRT) rem- ains the most common approach for the treat- ment of brain metastasis ...precise radiotherapy plus WBRT could enhance the survival of patients ...
7
Stereotactic radiosurgery (SRS) in the modern management of patients with brain metastases
... to whole brain radiotherapy (WBRT) ...of brain metastases (“limited number” customarily means ...blood brain barrier and/or stimulate an immune ...limited brain metastases, and ...
13
Radiotherapy improves the survival of patients with extensive-disease small-cell lung cancer: a propensity score matched analysis of Surveillance, Epidemiology, and End Results database
... of whole brain radiotherapy (WBRT) in patients who developed brain metastases might be owing to 1) brain metastasis in SCLC indicating a systematic disease with very dismal prognosis as ...
11
Breast Cancer Therapies Present and Future
... temozolomide is an alkylating agent and breast cancers highly expresses O(6)-methyl-guanine-DNA-methyl-trans- ferase (MGMT) which functions to repair DNA damage resulting from alkylating agents. Thus for at least breast ...
11
Subcortical vascular damages for post radiation brain radiotherapy
... during whole brain radiotherapy (WBRT)-largely employed up to ten years ago for brain lymphomas, for example, may provide a net gain in control neurocognitive decline (Vinai et ...of ...
9
Sex differences in the brain: a whole body perspective
... Recent work also suggests that the microbiota has acute as well as programming effects on the brain and behavior. For example, mice treated with valproic acid on gestational day 11 are well-established animal ...
15
Whole brain teaching in the Philippines: Teaching strategy for addressing motivation and academic performance
... of brain-based learning in the online ...new brain-based ideologies since compared to other established theories, brain-based approaches are still in their ...is Brain-based learning (DepEd, ...
12
Reflexivity and whole brain thinking : An exploration
... The aim of the model is to encourage reflexivity about prioritising for value-add by asking high gain questions how the participant manages his/her time and prioritises tasks. I begin by asking the participant to think ...
343