wnt/beta-catenin pathway
Hypothesis of Opposite Interplay Between the Canonical WNT/beta-catenin Pathway and PPAR Gamma in Primary Central Nervous System Lymphomas
... diseases beta-catenin signaling inhibits PPAR gamma expression (Drygiannakis et ...a WNT target gene (Akinyeke and Stewart, ...of WNT/beta- catenin has been shown, and the use of ...
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Wnt/beta-catenin pathway: modulating anticancer immune response
... signaling pathway is required for self- renewal of ...β- catenin was activated during development of mixed- lineage leukemia (MLL) ...on Wnt/β-catenin pathway in addition to other ...
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Overexpression of CD300A inhibits progression of NSCLC through downregulating Wnt/β-catenin pathway
... in Wnt/ β -catenin pathway were detected by Western ...the Wnt/ β -catenin pathway in A549 and H1650 ...the Wnt/ β -catenin pathway was involved in the ...
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<p>Nr5a2 promotes tumor growth and metastasis of gastric cancer AGS cells by Wnt/beta-catenin signaling</p>
... the Wnt/b-catenin ...the Wnt/beta- catenin pathway by LiCl could also enhanced the level of ...and Wnt/beta-catenin pathway, and they may play a ...
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Circular RNAs: Regulators of Cancer-Related Signaling Pathways and Potential Diagnostic Biomarkers for Human Cancers
... CircRNAs are relatively stable in animal cells and can regulate the target gene expression in several ways. First, circRNAs, have a covalently closed loop with no 5'-3' polarity or poly A tail; the circular loop consists ...
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ABERRANT EXPRESSION OF WNT/BETA CATENIN SIGNALING PATHWAY AND IN VITRO CYTOTOXIC ACTIVITY OF TRADESCANTIA SPATHACEA MEDICINAL PLANT USED TO TREAT HUMAN BREAST ADENOCARCINOMA (MCF 7 CELL LINES)
... Especially, Wnt/β- catenin signaling pathway plays important role in stem cells self-renewal, differentiation and ...of Wnt/β- catenin signaling pathway induced variety of cancer ...
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MiR 92b inhibitor promoted glioma cell apoptosis via targeting DKK3 and blocking the Wnt/beta catenin signaling pathway
... the Wnt/beta-catenin signaling path- way, such as Bcl2, c-myc, c-Jun and ...of beta-catenin (Figure 4A), which suggested that miR-92b modulated beta-catenin via ...the ...
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LncRNA CASC11 promotes the cervical cancer progression by activating Wnt/beta-catenin signaling pathway
... [20]. Wnt/β-catenin is a canonical pathway that can participate in cell growth, regulation and ...signaling pathway is acti- vated, GSK3β kept as an inactive state, which facilitates the ...
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EpCAM- AN OLD CANCER ANTIGEN, TURNED ONCOGENIC RECEPTOR AND ITS TAGETING IMMUNOTHERAPY
... . Wnt binds to receptors of the Frizzled family on the ...to beta-catenin, which accumulates initially in the cytoplasm, and then enters the nucleus where it binds a lymphoid enhancer factor/T-cell ...
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Novel mutation G324C in WNT1 mapped in a large Pakistani family with severe recessively inherited Osteogenesis Imperfecta
... the WNT induced beta-catenin signaling ...signaling pathway have been reported also in other disorders with abnormal bone mass, suggest- ing that the pathway has an integral role in the ...
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Studies of the Wnt/Beta-catenin signalling pathway in chronic myeloid leukaemia
... of Wnt/β-catenin pathway target genes, which include C-MYC and CYCLIN D1 (see Figure ...of Wnt target gene transcription by inhibiting the ...
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Formation of synovial joints and articular cartilage
... Chondrocytes differentiate from mesenchymal progenitors and produce templates (anlagen) for the developing bones. Chondrocyte differentiation is controlled by Sox transcription factors. Templates for the neighbour bones ...
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Inactivation of the Wnt/β-catenin signaling pathway underlies inhibitory role of microRNA-129-5p in epithelial–mesenchymal transition and angiogenesis of prostate cancer by targeting ZIC2
... to inhibit endogenous peroxidase activity and sealed with 5% normal goat serum working solution (C1771, Beijing Applygen Technology Co., Ltd., Beijing, China). After incubation for 10–15 min at 37 °C, the sections were ...
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PubMedCentral-PMC5647938.pdf
... Immunohistochemical labeling of embryonic brain sections and isolated cortical progenitors was performed as described earlier (Higginbotham et al. 2013; Guo et al. 2015). The following prima- ry antibodies were used: ...
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Activation of Wnt/β-catenin signalling promotes mesenchymal stem cells to repair injured alveolar epithelium induced by lipopolysaccharide in mice
... Injury of the alveolar epithelium in ARDS is consid- ered to be a key factor in the leakage of protein-rich oedema fluid into the interstitium and alveolar space [34]. Many studies have found that MSC treatment sig- ...
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Regulation of Wnt/β-catenin signaling by posttranslational modifications
... the Wnt/ β -catenin pathway [150]. How canonical Wnt signaling regulates Gsk3 to inhibit β -catenin proteolysis remains largely ...in Wnt signaling re- mains an open question, ...
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Original Article MicroRNA-29 mediates TGFβ1-induced extracellular matrix synthesis by targeting wnt/β-catenin pathway in human orbital fibroblasts
... Abstract: Purpose: Transforming growth factor β1 (TGFβ1) is very important in the synthesis and degradation of extracellular matrix (ECM) and also in the mediation of human orbital fibroblasts (OFs) proliferation. ...
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Regulation Mechanism of Long Noncoding RNAs in Colon Cancer Development and Progression
... the Wnt/β-catenin cascade by binding to hnRNP-K, which can form a complex with GSK3β, TCF4, β-catenin, and AXIN to inhibit the degradation of ...
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Regulation of neuritogenesis in neuroblastoma cells by components of the Wnt signalling pathway
... Neuro-2a cells are derived from a mouse neuroblastoma, and were given to us by L Reichardt (UCSF, San Fransisco, CA, USA). COS-7 cells are African Green Monkey kidney cells, and were a gift from M Vivanco (Institute of ...
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Circular RNAs Regulate Cancer Onset and Progression via Wnt/β Catenin Signaling Pathway
... the Wnt/β-catenin pathway, which controls a plethora of cellular pro- cesses that drive cancer ...and Wnt/β-catenin signaling pathway presents potential diagnostic biomarkers and ...
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