Wnt signaling gene expression
Xenopus frizzled-4S, a splicing variant of Xfz4 is a context-dependent activator and inhibitor of Wnt/β-catenin signaling
... regulate Wnt/ β -catenin ...of Wnt/β-catenin signal- ing by the Frizzled ecto-domain is mediated by the Wnt coreceptor ...the Wnt-1/Xfz4S and Wnt5a/ECD8 complexes interact with the coreceptor ...
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Coordinate integrin and c Met signaling regulate Wnt gene expression during epithelial morphogenesis
... whether Wnt/ β -catenin activity was affected in the absence of α 3 β 1 integrin in vivo, utilizing embryos containing a Tcf-responsive lacZ transgene (Cheon et ...galactosidase expression was observed in ...
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Review Article Signaling pathway and molecular subgroups of medulloblastoma
... (miRNA) expression profiling and epi- genetic regulation, and they are important in the biology of ...miRNA expression profiling has revealed differ- entially expressed miRNAs in MB ...the gene PTCH ...
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Butyrate induced changes in Wnt signaling specific gene expression in colorectal cancer cells
... butyrate-mediated Wnt hyperactivation, we performed total human genome microarray analyses on HCT-116 CRC cells in the presence or absence of a physiologically relevant concentration of ...in Wnt-specific ...
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A Genome-Wide RNA Interference Screen Identifies a Role for Wnt/β-Catenin Signaling during Rift Valley Fever Virus Infection
... overall gene ex- pression, using TransIT-LT1 transfection reagent (Mirus Bio) according to the manufacturer’s ...TaqMan Gene Expression master mix were purchased from Applied Biosystems, and ...
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Original Article MicroRNA-374a promotes osteogenic differentiation of periodontal ligament stem cells through directly targeting APC/Wnt/β-catenin signaling pathway
... miRNA expression profile before and after the osteoblastic differentiation of PDLSCs was assessed by microarray analysis and selected miRNAs were validated by quantitative RT-PCR ...the Wnt/β-catenin ...
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Role of canonical Wnt signaling/β catenin via Dermo1 in cranial dermal cell development
... Full-length pcDNA3-Dermo1-Flag (from D. Sosic and E. Olson, University of Texas Southwestern Medical Center, TX, USA) and pcDNA3-5 ⬘ UT-Flag (from V. Lefebvre, Lerner Research Institute, Cleveland Clinic Foundation, OH, ...
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Wang, Jing (2019): Deciphering the roles of LGR6 in WNT and EMT signaling in pancreatic cancer. Dissertation, LMU München: Medizinische Fakultät
... used Gene Set Enrichment Analysis (GSEA) and found that LGR6 inversely correlated with EMT signatures in ...LGR6 expression pattern in the above-mentioned four PDAC cell ...no expression was detected ...
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Reiterated Wnt signaling during zebrafish neural crest development
... of Wnt targets in vivo, ∆Tcf was induced by heat shock in fish that were transgenic for TOPdGFP, a Wnt-responsive reporter construct that contains a destabilized variant GFP under the control of four Lef ...
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De novo HAPLN1 expression hallmarks Wnt-induced stem cell and fibrogenic networks leading to aggressive human hepatocellular carcinomas
... HAPLN1 expression correlated with the stem cell marker PROM1 and with cytoplasmic β-catenin (Figure ...enhanced Wnt signaling without β-catenin gene mutations [1, ...
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6. R.Prakash and S.Anandakumar
... of Wnt/canonical pathway was identified in the development of begin and malignant breast ...over expression of Wnt ligands and decreased activity of Wnt/Ca 2+ pathway (Howe and Brown, 2004; ...
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The zic1 gene is an activator of Wnt signaling
... and wnt genes, we utilized animal cap ...show expression of either the pan-neural gene N-CAM or the anterior neural marker otx2 ...otx2 expression (lane ...
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Gene expression profiling of early intervertebral disc degeneration reveals a down regulation of canonical Wnt signaling and caveolin 1 expression: implications for development of regenerative strategies
... Canine Gene Expres- sion Microarrays V1 (G2519F, Agilent Technologies, Amstelveen, the Netherlands) ...of gene expression were compared between the three stages of IVD degeneration (NC-rich, mixed, ...
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FGF dependent regulation of Zfhx1b gene expression promotes the formation of definitive neural stem cells in the mouse anterior neurectoderm
... First, Wnt inhibition acts upstream in the lineage, enhancing neural specification in general and/or the specification of pNSCs within the ...tively, Wnt inhibition may also influence the transition from a ...
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The anti-apoptotic PON2 protein is Wnt/β-catenin-regulated and correlates with radiotherapy resistance in OSCC patients
... of Wnt stimulation, the inactivation of GSK-3β causes a relief of the β-cat-destabilizing phosphorylation, allowing ß-cat to migrate into the nucleus for activation of transcription factors of the T-cell factor ...
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Wnt signaling is a key mediator of Cdx1 expression in vivo
... Hox gene expression is subject to Notch-mediated signaling in the anterior presomitic mesoderm (Zakany et ...of Wnt signaling in this ...direct Wnt target, it is conceivable that ...
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Identification of COX5B as a novel biomarker in high-grade glioma patients
... the Gene Expression Omnibus ...Using gene expression signatures, we identified three oncogenic pathways (MAPK signaling pathway, Wnt signaling pathway, and ErbB ...
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The Effects of Tracheal Occlusion on Wnt Signaling in a Rabbit Model of Congenital Diaphragmatic Hernia
... species-specific gene expression, the mode and timing of CDH induction, and the stage of lung development at which time the lung tissue was ...WIF1 expression in a sample of lung tissue collected ...
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Increased Wnt and Notch signaling: a clue to the renal disease in Schimke immuno-osseous dysplasia?
... in gene expression is incompletely ...a gene or of the genes encoding the tran- scriptional regulators of that ...modulate gene expression ...alter gene expression [35, ...
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Attenuation of Wnt/β-catenin signaling in patients with Stevens-Johnson syndrome and toxic epidermal necrolysis
... The Wnt signaling pathway is evolutionarily conserved and is implicated in a large variety of developmental processes including specification of cell fate and maintenance of stem cell pluripotency [15, ...
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