Yes associated protein 1
Original Article Yes-associated protein 1 promotes bladder cancer invasion by regulating epithelial-mesenchymal transition
... March 1, 2019; Published March 15, 2019 Abstract: Purpose: To investigate the expression of Yes-associated protein 1 (YAP1) in bladder cancer, and to study its role in regulating ...
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Polyomavirus Small t Antigen Interacts with Yes-Associated Protein To Regulate Cell Survival and Differentiation
... both Yes-associated protein 1 (YAP1) and YAP2, inte- gral parts of the Hippo signaling pathway, which is a subject of increasing interest in human ...with protein phospha- tase 2A ...
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<p>Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis</p>
... The protein samples were run on sodium dodecyl sulfate polyacryla- mide gel electrophoresis (SDS-PAGE), and transferred onto polyvinylidene fl uoride (PVDF) membrane (Thermo Fisher Scienti fi ...(anti-YAP, ...
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Aberrant methylation of yes-associated protein (YAP1) as a potential biomarker in breast cancer
... Breast cancer (BC) is considered the most common malignancy in females, and it accounts for approxi- mately 32.04% of the reported cancers in Egyptian women [1]. Cancer biomarkers’ research has shown that not only ...
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Yes associated protein (YAP) is a negative regulator of chondrogenesis in mesenchymal stem cells
... after 1 day of culture in micromass prior to initiation of TGF-β1 treatment (Figure ...decreased 1 day after plating in micromass (Figure ...file 1). Downregulation of YAP at the protein level ...
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Yes-Associated Protein (Yap) Is Necessary for Ciliogenesis and Morphogenesis during Pronephros Development in Zebrafish (Danio Rerio)
... Cilia are microtubule-based organelles extend- ing outward from the basal body and ubiquitously exist in almost all vertebrates. Cilia function in fluid flow generation and integration of environmental cues, playing a ...
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Yes-Associated Protein (Yap) Is Required for Early Embryonic Development in Zebrafish (Danio Rerio)
... and tails that bent toward the abdomen, moderate morphants had short bodies and curved trunks, and severe morphants had small trunks and completely indistinct bodies. Mortality was calculated at 48 hpf (Fig. 1E). No ...
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Original Article Spliceosome-associated factor catenin b-like 1 accelerates ovarian cancer progression by inducing expression and nuclear accumulation of yes-associated protein
... The Hippo pathway is known to play an impor- tant role in regulating cell proliferation and organ size, in both Drosophila and mammals. In mammals, the Hippo pathway consists of a highly conserved kinase cascade, ...
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Original Article Expression of Yes-associated protein (YAP) in metastatic breast cancer
... September 1, 2015; Published September 15, 2015 Abstract: The purpose of this study was to investigate the expression of Yes-associated protein (YAP) in differ- ent metastatic sites in ...
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ORIGINALRESEARCH Curcumin Inhibits the Tumorigenesis of Breast Cancer by Blocking Tafazzin/Yes-Associated Protein Axis
... Cell invasion was detected using transwell chamber (Corning, NY, USA). Brie fl y, cells were seeded in the upper chamber pre-coated with matrigel at a density of 1 × 10 5 /chamber. The medium containing 10% FBS was ...
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Original Article Overexpression of yes-associated protein contributes to apoptosis of lung cancer
... The plasmid of pcDNA3.1-hYAP was a kind gift from Dr Subham Basu (Cancer Research UK, London, UK). The plasmid of pOTB7-TP53 was purchased Proteintach (Proteintach, China) pcDNA3.1-hYAP or pOTB7-TP53 control or plas- mid ...
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The role of Yes-associated protein (YAP) in vertebrate development
... In an unbiased screen for binding partners to the proline rich amino terminus of hYAP (1-57), it was found that hnRNP U bound to this region of YAP (Howell et al., 2004). By radiolabeling cells with [ 32 ...
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Original Article Expression of Yes-associated protein (YAP) in breast phyllodes tumor
... of Yes-associated protein (YAP) and its phosphorylated form (pYAP) in phyllodes tumor (PT) of human breast and verify the clinical ...were associated with shorter disease-free survival (DFS) ...
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Indecisiveness, Undesirability and Overload Revealed Through Rational Choice Deferral
... In the CDA model the agent has an incomplete preference relation % and chooses a maximizer of this relation as in (1) if one exists. If not, and he is faced with a problem ( A, s ) , then he chooses the status quo ...
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Functional outcome of extrarticular distal tibia fractures treated by Intramedullary nailing
... The functional outcomes assessed, when analysed, revealed the fact that worse functional outcomes were not related with age or associated injuries. It was associated with the quality of reduction of the ...
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Are we there yet? Analyzing architecture description languages for formal analysis, usability, and realizability
... either, thus making early analysis of system architectures difficult, if not impossible. This decreases substantially the benefit of having an architectural description of a system. Such specifications are difficult to ...
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A Study on Clinical Profile of Childhood Asthma and Its Comorbidities
... animals, mud flooring , walls and regular domestic cow dung’s usage in rural homes can increase the load of microbial components including endotoxin as well as other TLR ligands, hence reducing the subsequent risk of ...
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Study of Bone Density in Menopausal and Perimenopausal Women
... The relation between bone mineral density and fracture risk in untreated patients has been evaluated prospectively in several studies. A decrease in BMD is associated with increased risk of fracture. The ...
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Summary of the positions of the Member States and the European Parliament on the 1996 Intergovernmental Conference. Fourth update, 30 September 1996
... NEGOTIATIONS reducel'!_occdures to three• yes yes yes number ofMEPs: 700 yes yes yes distribution of scats: present formula yes yes yes ycsiR yes yes yes yes yea yes yea yes yes yes yes [r] ...
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Original Article LATS2-mediated YAP1 phosphorylation is involved in HCC tumorigenesis
... tivity [7]. Reduced LATS2 expression occurred in prostate tumors and LATS2 negatively modu- lated androgen receptor-regulated gene tran- scription, indicating that LATS2 may also play important role on prostate cancer ...
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