[PDF] Top 20 A revised model of platelet aggregation

... of platelet–platelet adhesion ...tethered platelet. Translo- cation was defined as platelet movement more than 1 cell diameter from the point of initial ...period. Platelet-imaging ... See full document

... Because platelet receptors mediate platelet adhesion and aggregation, we next studied the changes in the abundance of these receptors on platelets induced by human colon adeno- carcinoma ...the ... See full document

... this platelet HMGB1-dependent “aggregation peak” at this specific time point is unclear, although it may rep- resent the point of maximal HMGB1 expression and/or release by circulating platelets in mice ... See full document

... for: platelet signaling (neural network trained by pairwise agonist scanning, PAS-NN), platelet positions (lattice kinetic Monte Carlo, LKMC), wall-generated thrombin and platelet-released ... See full document

... simple model of platelet stimulus-response coupling that includes two mechanisms for activation; aggregation-mediated activation is inhibited by indomethacin, while direct activation does not depend ... See full document

... of platelet aggregation was evaluated in washed rabbit and human ...rat model. All extracts inhibited platelet aggregation in a dose-dependent manner as well as TXA 2 production by ... See full document

... similar model to Grabowski ...improved model could differentiate between activated and unactivated platelets where activated platelets were more likely to attach to the biomaterial surface and other ...his ... See full document

... A no-slip boundary condition was imposed on the interface of the bound platelets and the fluid. For small, dense platelet deposits, the flow within the clot is likely to be small. For larger structures, pressure ... See full document

... Since the most common cause of mortality in COPD is due to cardiovascular complications it is of paramount importance that we elucidate the exact mechanism involved in the platelet activation in COPD. Our study ... See full document

... heterotypic aggregation was abrogated by treatment with a selectin inhibitor in Berkeley mice ...neutrophil-platelet aggregation (Figure 7, ... See full document

... to platelet activation, we studied the correlation of platelet aggregation and ATP secretion with [Cai2+] as determined by 2-methyl-6-methoxy 8- nitroquinoline (quin2) and aequorin in response to ... See full document

... Acetyl glyceryl ether phosphorylcholine AGEPC induced dose-dependent platelet aggregation and release of [3H]serotonin and platelet factor 4 in citrated human platelet-rich plasma.. ADP [r] ... See full document

... of platelet mass in blood volume) were determined by electronic-automatic method with the help of hematological analyzer BC- 3000 PLUS (the firm “Shenzhen Mindray Bio-Medical Electronics ... See full document

... the platelet is an unusual cell; it does n o t have a nucleus and, therefore, is unable to synthesize ...the platelet is pre­ regulated by the bone marrow derived megakaryocyte ...the platelet ... See full document

... This aggregation response is abolished after digestion of the fixed platelets with ...ristocetin-induced aggregation of fixed washed platelets in buffer and normal platelets in platelet-rich ...a ... See full document

... after platelet activation Multiplate™ analyzer records impedance between two electrodes during a period of six minutes reflecting platelet aggregation on the surface of the ...of aggregation ... See full document

... Injecting SK into rabbits (10,000 U/kg body weight) caused a transitory drop of platelet count. These platelets lost part of their serotonin and fibrinogen. The administration of Persantin or of epsilon ... See full document

... of platelet-rich plasma (PRP) stored for 3-4 days and platelet concentrates (PC) stored for 24 ...in platelet count, pH, or plasma glucose. Platelet glycogen fell dramatically both chemically ... See full document

... on platelet lipids or platelet ...in platelet membrane cholesterol was three-fold that of the granule ...epinephrine-induced aggregation (P less than 0.001) and 15-fold increase to ADP ... See full document

... markers in case of cystic fibrosis, we further analyzed ROC-curves using the obtained data. TRAP-test has the best diagnostic value among the tests that reflect the aggregation function of platelets (Figure 4), ... See full document